Development of a Swine Whole Eye Transplant Ex Vivo Perfusion Protocol
This study establishes the first subnormothermic machine perfusion protocol for whole eye transplants in a swine model, enabling up to 18 h of preservation with stable metabolic function, limited edema, and recovery of mydriasis. ABSTRACT Background The first human Whole Eye Transplant (WET) has sparked new hope for patients who have lost vision due to
Haïzam Oubari +8 more
wiley +1 more source
Hormonal Treatment During Ex Vivo Lung Perfusion Ameliorates Brain Death Induced Inflammation
Treatment of lungs during ex vivo perfusion with 17β‐estradiol and methylprednisolone improved graft quality. In females, treated and non‐treated groups presented reduced leukocyte infiltration and only the treatment improved perfusion flow. In males, treatment improved lung function by increasing compliance, paO2, and perfusion flow.
Marina Vidal‐dos‐Santos +9 more
wiley +1 more source
Pooled Incidence of Heparin-Induced Thrombocytopenia and Anti-Platelet Factor 4 Antibody Formation Among Adults: A Systematic Review and Meta-Analysis. [PDF]
Devarapalli A +3 more
europepmc +1 more source
An In Vitro System for Studying Toxin Transport Across Hemodialysis Membranes
Development of an in vitro hemodialysis (HD) system based on mini dialyzers for evaluating hemodialysis membranes under physiologically relevant conditions. ABSTRACT Background Healthy kidneys regulate acid–base balance and electrolytes, produce hormones, and clear excess fluids and uremic toxins.
M. Torrents‐Yeste +7 more
wiley +1 more source
Efficacy and safety evaluation of thromboprophylaxis strategies for central venous catheter-related thrombosis in cancer patients: a bayesian network meta-analysis and bibliometric analysis. [PDF]
Meng M +13 more
europepmc +1 more source
eOGO is an uncommon adverse event in patients on long‐term LVAD support. Thirty‐one eOGO patients were identified in a single‐centre HM3 implantation program. Twenty patients underwent percutaneous stenting. This treatment resulted in immediate LVAD flow improvement and yielded satisfactory quality‐of‐life results, with 62.5% patients assigned a fair ...
Anna Huang +14 more
wiley +1 more source
Don't neglect the non-thrombotic manifestations of antiphospholipid syndrome in children - autoimmune hemolytic anemia and myocarditis: a case report and literature review. [PDF]
Cui W +9 more
europepmc +1 more source
Hierarchical clustering of viscoelastic and conventional coagulation parameters identified three distinct phenotypes in V‐V ECMO patients, revealing substantial APTT–CK‐R discordance and highlighting the value of TEG‐derived markers for detecting coagulopathy not captured by standard monitoring.
Daisuke Irimada +9 more
wiley +1 more source
In this meta‐analysis of 2 775 adult ECMO patients from non‐randomized studies, direct thrombin inhibitors and low‐molecular‐weight heparins demonstrated a favorable efficacy and safety profile over unfractionated heparin. These findings suggest them to be effective alternatives to unfractionated heparin, underscoring the urgent need for randomized ...
Vincenz Scharner +7 more
wiley +1 more source
Direct oral anticoagulants in thrombocytopenic patients with cancer. [PDF]
Di Carlo C, Cervi A.
europepmc +1 more source

