ABSTRACT Climate change and rising ambient temperatures increasingly challenge sheep production systems in arid and semi‐arid regions, particularly during the summer breeding season. This study evaluated the effects of heat stress and direct solar exposure on physiological responses, metabolic profile, and reproductive performance of Barbarine ewes, a ...
Samia Khnissi +4 more
wiley +1 more source
Comprehensive Genetic and Molecular Characterization Confirms Hepatic Stellate Cell Origin of the Immortal Col-GFP HSC Line. [PDF]
Buitkamp LF +7 more
europepmc +1 more source
Abstract Background Diagnostic error is a major patient safety concern in hospitals, yet most studies have focused on selected high‐risk subgroups, leaving the broader general internal medicine inpatient population understudied. Objectives To determine the incidence, contributing factors, resulting harm, and predictors of diagnostic error in medical ...
Caterina E. Marx +9 more
wiley +1 more source
Disturbance of cytoskeleton induced by ligustilide promotes hepatic stellate cell senescence and ameliorates liver fibrosis. [PDF]
Qu J +12 more
europepmc +1 more source
Human umbilical cord mesenchymal stem cells attenuate liver fibrosis in mice and inhibit hepatic stellate cell activation by secreting soluble factors. [PDF]
Zhou Q +8 more
europepmc +1 more source
The pivotal role of IL-17A in hepatic stellate cell activation. [PDF]
Poniewierska-Baran A +4 more
europepmc +1 more source
He-He-Shu-Yang formula alleviates liver fibrosis by inhibiting hepatic stellate cell activation <i>in vivo</i> and <i>in vitro</i>. [PDF]
Zeng FL +5 more
europepmc +1 more source
GHSR-Foxo1 Signaling in Macrophages Promotes Liver Fibrosis via Inflammatory Response and Hepatic Stellate Cell Activation. [PDF]
Kim DM +9 more
europepmc +1 more source
Hepatic stellate cell-specific miR-214 expression alleviates liver fibrosis without boosting steatosis and inflammation. [PDF]
Zhao F +8 more
europepmc +1 more source
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Mechanisms of hepatic stellate cell activation
Nature Reviews Gastroenterology and Hepatology, 2017Hepatic fibrosis is a dynamic process characterized by the net accumulation of extracellular matrix resulting from chronic liver injury of any aetiology, including viral infection, alcoholic liver disease and NASH. Activation of hepatic stellate cells (HSCs) - transdifferentiation of quiescent, vitamin-A-storing cells into proliferative, fibrogenic ...
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