Results 301 to 310 of about 912,795 (359)

Treatment of Chronic Hepatitis B

Current Pharmaceutical Design, 2002
Infection with the hepatitis B virus has switched over the last 20 years from the classical HBeAg positive serologic pattern to a HBeAg negative form that is linked, in the Mediterranean basin, with the epidemiologic replacement of the causative wild-type of virus B with mutant variants, whereby mutations in the core-promoter and in the pre-core region
M, Lagget, M, Rizzetto
openaire   +2 more sources

Gut microbiota dysbiosis in patients with hepatitis B virus–induced chronic liver disease covering chronic hepatitis, liver cirrhosis and hepatocellular carcinoma

Journal of Viral Hepatitis, 2019
The information regarding the effect of hepatitis B virus (HBV) infection on gut microbiota and the relationship between gut microbiota dysbiosis and hepatitis B virus–induced chronic liver disease (HBVCLD) is limited.
Yongbin Zeng, Shan-Shan Chen, Ya Fu, Wennan Wu, Tianbin Chen, J. Chen, Bin Yang, Q. Ou   +7 more
semanticscholar   +1 more source

Pregenomic HBV RNA and Hepatitis B Core‐Related Antigen Predict Outcomes in Hepatitis B e Antigen–Negative Chronic Hepatitis B Patients Suppressed on Nucleos(T)ide Analogue Therapy

Hepatology, 2019
A dichotomous separation of hepatitis B viral DNA and hepatitis B surface antigen (HBsAg) concentrations occurs during the natural history and treatment of chronic hepatitis B.
I. Carey, Jeffrey Gersch, Bo Wang, Christiana Moigboi, M. Kuhns, G. Cloherty, G. Dusheiko, K. Agarwal   +7 more
semanticscholar   +1 more source

Roadmap to functional cure of chronic hepatitis B: An expert consensus

Journal of Viral Hepatitis, 2019
Hepatitis B virus (HBV) infection continues to be a major public health issue worldwide. HBsAg loss is associated with functional remission and improved long‐term outcome, and is considered to be a ‘functional cure’ (also referred to as clinical or ...
Q. Ning, Di Wu, Guiqiang Wang, H. Ren, zhi-liang gao, P. Hu, Meifang Han, Yan Wang, Wenhong Zhang, F. Lu, Fu-sheng Wang   +10 more
semanticscholar   +1 more source

Treatment of chronic hepatitis B

Journal of Viral Hepatitis, 1994
SUMMARY.Chronic infection with the hepatitis B virus (HBV) is a major cause of worldwide morbidity and mortality. A large number of therapeutic approaches has been tried, including interferon (IFN), nucleoside analogues and immunomodulators. To date controlled clinical trials have shown that only IFN is of long‐term value but many patients fail to ...
openaire   +2 more sources

Chronic Hepatitis B Infection

Clinics in Liver Disease, 2012
The management of chronic hepatitis B virus (HBV) infection requires understanding the natural history of the disease as well as the risks, benefits, and limitations of the therapeutic options. This article covers the principles governing when to start antiviral therapy, discusses recent advances using hepatitis B surface antigen quantification to ...
Alexander, Kuo, Robert, Gish
openaire   +2 more sources

Chronic hepatitis B virus infection.

The Lancet, 2018
Chronic hepatitis B virus infection is a global public health threat that causes considerable liver-related morbidity and mortality. It is acquired at birth or later via person-to-person transmission.
W. Seto, Y. Lo, J. Pawlotsky, M. Yuen
semanticscholar   +1 more source

Management of chronic hepatitis B

Gastroenterology Clinics of North America, 2004
Chronic hepatitis B (CHB) is a major worldwide cause of chronic liver disease and a significant public health issue. Three predominant clinical presentations are recognized: hepatitis B e antigen(HBeAg) or typical CHB, HBeAg-negative or atypical CHB, and inactive CHB.
Marc G, Ghany, Edward C, Doo
openaire   +2 more sources

Treatment of Chronic Hepatitis B

Minerva gastroenterologica e dietologica, 2010
Approximately 350-420 million people worldwide are chronically infected with hepatitis B virus (HBV). Chronic hepatitis B can result in liver cirrhosis, hepatic decompensation, and hepatocellular carcinoma. Reactivation of hepatitis B is possible in patients with inactive or resolved hepatitis B often leading to liver failure.
Lai, CL, Yuen, RMF
openaire   +4 more sources

The management of chronic hepatitis B

The American Journal of Medicine, 1994
The immediate goals of hepatitis B virus (HBV) therapy are to suppress the histologic progression of the disease and diminish infectivity. Although many drugs have been used in the treatment of this condition, only interferon has proven to be consistently effective.
openaire   +2 more sources