Results 121 to 130 of about 75,491 (253)

High‐Efficiency Genome Editing of Chlorella sp. by CRISPR/Cas9

open access: yes
Plant Biotechnology Journal, EarlyView.
Xinyu Cui   +5 more
wiley   +1 more source

Novel Wide‐Spectrum Virucidal Lipid Nanoparticles

open access: yesSmall, Volume 22, Issue 7, 2 February 2026.
POSTAN is a novel broad‐spectrum antiviral nanoparticle that combines safety with potent virucidal activity. Composed of biocompatible lipids, it mimics heparan sulfate proteoglycans and lipid rafts exploited by viruses, thereby dismantling viral envelopes and blocking replication.
Yugo Araújo Martins   +10 more
wiley   +1 more source

Chronic delta hepatitis: from discovery to new treatments

open access: yesOne Health & Risk Management, 2021
Introduction. Hepatitis delta virus (HDV) is a small, defective RNA virus that is related more to plant viroids than to other human pathogens. Material and methods.
Adela TURCANU, Suhaib TAHIR WANI
doaj  

Prediction and statistics of pseudoknots in RNA structures using exactly clustered stochastic simulations

open access: yes, 2003
Ab initio RNA secondary structure predictions have long dismissed helices interior to loops, so-called pseudoknots, despite their structural importance.
A. Xayaphoummine   +22 more
core   +3 more sources

Ten‐Year Follow‐Up After 96 Weeks Treatment With Peginterferon Plus Tenofovir in Hepatitis D (HIDIT‐II): Improved Clinical Outcome After Combination Therapy

open access: yesUnited European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
ABSTRACT Background Chronic delta hepatitis represents a major health burden. Until recently, pegylated interferon‐alfa‐2a (PEG‐IFNα) therapy was the only treatment option for patients infected with hepatitis D virus (HDV). The aim of this study was to evaluate 10‐year long‐term clinical and virological outcomes after 96 weeks of treatment with PEG ...
Cihan Yurdaydin   +17 more
wiley   +1 more source

Developing RT-qPCR Kit for Detection and Quantification of Hepatitis D Virus Unique Genome

open access: yesCyprus Journal of Medical Sciences
BACKGROUND/AIMS: Hepatitis D virus (HDV) is a significant global health problem identified in the 1970s in Hepatitis B virus (HBV) positive patients.
Kıvanç Günhan   +9 more
doaj   +1 more source

Distinct 5′ UTR Requirements for Translation of the Bicistronic X/P mRNA Among Avian Orthobornaviruses

open access: yesMicrobiology and Immunology, Volume 70, Issue 2, Page 80-90, February 2026.
ABSTRACT Orthobornaviruses express X and the phosphoprotein (P) from a bicistronic X/P mRNA, and these proteins regulate polymerase activity. In mammalian orthobornaviruses, the 5′ untranslated region (5′ UTR) of the X/P mRNA controls the translational balance between X and P and thereby promotes efficient replication.
Meng‐Chi Wu   +7 more
wiley   +1 more source

Prevalence of established and emerging biomarkers of immune checkpoint inhibitor response in advanced hepatocellular carcinoma. [PDF]

open access: yes, 2019
The clinical deployment of immune checkpoint inhibitors (ICIs) has created a tandem drive for the identification of biomarkers linked to benefit. Comprehensive genomic profiling was performed to evaluate the frequency of genomic biomarkers of ICI ...
Ali, Siraj M   +10 more
core   +1 more source

Exacerbation of Anti‐Cytomegalovirus Immunity and Mobilization of γ9δ1 T Cells During the Acute Phase of Hepatitis E Virus Infection

open access: yesMicrobiology and Immunology, Volume 70, Issue 2, Page 113-124, February 2026.
ABSTRACT HEV causes chronic infections that are detrimental to immunocompromised patients. Previous studies showed alterations of γδ T cell subsets at the acute phase of HEV infection. To assess a possible role of CMV, we have examined the frequencies and responses to CMV and HEV of blood γδ T cell subsets from control donors and acute‐phase HEV ...
Marion Retailleau   +5 more
wiley   +1 more source

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