Results 71 to 80 of about 334,700 (354)

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

FEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez, Cristina Velez‐delValle, Claudia Patricia Hernández‐Mosqueira, Walid Kuri‐Harcuch   +3 more
wiley   +1 more source

Contact Process under heavy-tailed renewals on finite graphs [PDF]

Bernoulli 27(3), 2021, 1745-1763, 2019
We investigate a non-Markovian analogue of the Harris contact process in a finite connected graph G=(V,E): an individual is attached to each site x in V, and it can be infected or healthy; the infection propagates to healthy neighbors just as in the usual contact process, according to independent exponential times with a fixed rate lambda>0; however ...
arxiv   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Improvement Effect of Lotus Leaf Flavonoids on Carbon Tetrachloride-Induced Liver Injury in Mice

Biomedicines, 2020
In this study, the effect of lotus leaf flavonoids (LLF) on carbon tetrachloride (CCl4)-induced liver injury in mice was studied. CCl4 was injected intraperitoneally to induce liver injury in Kunming mice.
Tongji Liu, Fang Tan, Xingyao Long, Yanni Pan, Jianfei Mu, Xianrong Zhou, Runkun Yi, Xin Zhao   +7 more
doaj   +1 more source

Re-cycling of DNA-containing Capsids Enhances Hepatitis B Virus Infection [PDF]

arXiv, 2023
Hepatitis B virus infection is a deadly liver disease. A part of newly produced HBV DNA-containing capsids are reused as a core particle in HBV replication. It is investigated that the recycling of HBV capsids greatly affects the intracellular dynamics of HBV infection.
arxiv  

Cell proliferation and oncogene expression after bile duct ligation in the rat: Evidence of a specific growth effect on bile duct cells [PDF]

, 1995
The proliferative response of the rat liver was measured after temporary or permanent total biliary obstruction (BDO) and in different regions after selective ligation of the lobar ducts draining the right 60% of the hepatic mass.
Azzarone, A, Bouzahzah, B, Carr, B, Francavilla, A, Panella, C, Polimeno, L, Starzl, TE, Subbotin, V, Zeng, QH   +8 more
core   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

g factor of Li-like ions with nonzero nuclear spin [PDF]

Optics and Spectroscopy, Vol. 104, No. 5, 2008, p. 637, 2007
The fully relativistic theory of the g factor of Li-like ions with nonzero nuclear spin is considered for the (1s)^2 2s state. The magnetic-dipole hyperfine-interaction correction to the atomic g factor is calculated including the one-electron contributions as well as the interelectronic-interaction effects of order 1/Z.
arxiv   +1 more source

Best practice guidelines for the molecular genetic diagnosis of maturity-onset diabetes of the young [PDF]

, 2008
Member of the EMQN MODY group: Gisela GasparAIMS/HYPOTHESIS: Mutations in the GCK and HNF1A genes are the most common cause of the monogenic forms of diabetes known as 'maturity-onset diabetes of the young'. GCK encodes the glucokinase enzyme, which acts
A Stride, A Stride, A. T. Hattersley, AL Gloyn, American Diabetes Association, AT Hattersley, BN Cockburn, C Bellanne-Chantelot, C Gragnoli, C. Bellanné-Chantelot, D Stoffers, E Feigerlova, EL Edghill, ER Pearson, ER Pearson, ER Pearson, ER Pearson, F Sun, FL Chartier, G Spyer, H Lenderman, H Raeder, H Raeder, H Thomas, JS Collins, LW Harries, LW Harries, LW Harries, M Shepherd, M Shepherd, MP Bulman, MT Malecki, O Gill-Carey, R Menzel, RB Tattersall, RB Tattersall, S Ellard, S Ellard, S Ellard, S Schnyder, S. Ellard, SK Hansen, SS Fajans, SS Fajans, SY Kristinsson, T Drewes, TM Frayling, Y Horikawa   +47 more
core   +2 more sources

Association of CYP1B1 Germ Line Mutations with Hepatocyte Nuclear Factor 1α–Mutated Hepatocellular Adenoma [PDF]

Cancer Research, 2007
AbstractBiallelic somatic mutations of TCF1 coding for hepatocyte nuclear factor 1α (HNF1α) are found in 50% of the hepatocellular adenoma (HCA) cases usually associated with oral contraception. In rare cases, HNF1α germ line mutations could also predispose to familial adenomatosis. In order to identify new genetic factors predisposing to HNF1α-mutated
Jeannot, Emmanuelle, Poussin, Karine, Chiche, Laurence, Bacq, Yannick, Sturm, Nathalie, Scoazec, Jean-Yves, Buffet, Catherine, Nhieu, Jeanne Tran Van, Bellanné-Chantelot, Christine, de Toma, Claudia, Laurent-Puig, Pierre, Bioulac-Sage, Paulette, Zucman-Rossi, Jessica   +12 more
openaire   +6 more sources