Results 11 to 20 of about 136,980 (341)

Transcriptional Regulation of the Angptl8 Gene by Hepatocyte Nuclear Factor-1 in the Murine Liver. [PDF]

Sci Rep, 2020
Watanabe T, Ozawa A, Masuda S, Yoshino S, Ishida E, Kondo Y, Matsumoto S, Katano-Toki A, Horiguchi K, Nakajima Y, Yamada E, Tomaru T, Saito T, Ishii S, Shibusawa N, Okada S, Satoh T, Yamada M.   +17 more
europepmc   +3 more sources

MicroRNA-375 Is Induced in Cisplatin Nephrotoxicity to Repress Hepatocyte Nuclear Factor 1-β. [PDF]

J Biol Chem, 2017
Hao J, Lou Q, Wei Q, Mei S, Li L, Wu G, Mi QS, Mei C, Dong Z.   +8 more
europepmc   +3 more sources

Genetic Study of Hepatocyte Nuclear Factor 1 Alpha Variants in Development of Early-Onset Diabetes Type 2 and Maturity-Onset Diabetes of the Young 3 in Iran. [PDF]

Adv Biomed Res, 2019
Mohammadi A, Eskandari A, Sarmadi A, Rahimi M, Iraj B, Hashemipour M, Chaleshtori MH, Tabatabaiefar MA.   +7 more
europepmc   +2 more sources

Effects of C2-Ceramide and Oltipraz on Hepatocyte Nuclear Factor-1 and Glutathione S-Transferase A1 in Acetaminophen-Mediated Acute Mice Liver Injury. [PDF]

Front Pharmacol, 2018
Ma X, Chang Y, Zhang Y, Muhammad I, Shi C, Li R, Li C, Li Z, Lin Y, Han Q, Liu F.   +10 more
europepmc   +3 more sources

Function annotation of hepatic retinoid x receptor α based on genome-wide DNA binding and transcriptome profiling. [PDF]

, 2012
BackgroundRetinoid x receptor α (RXRα) is abundantly expressed in the liver and is essential for the function of other nuclear receptors. Using chromatin immunoprecipitation sequencing and mRNA profiling data generated from wild type and RXRα-null mouse ...
Fang, Jianwen, Fang, Yaping, He, Yuqi, Liu, Hui-Xin, Wan, Yu-Jui Yvonne, Zhan, Qi   +5 more
core   +11 more sources

Maturity‐onset diabetes of the young type 5, presenting as diabetic ketoacidosis with alkalemia: A report of a case

Journal of Diabetes Investigation, 2022
A 34‐year‐old man visited our Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan, because of dry mouth and weight loss.
Akiko Hayakawa‐Iwamoto, Daisuke Aotani, Yuki Shimizu, Shota Kakoi, Chie Hasegawa, Shunsuke Itoh, Asami Fujii, Katsushi Takeda, Takashi Yagi, Hiroyuki Koyama, Kenro Imaeda, Kandai Nozu, China Nagano, Hiromi Kataoka, Tomohiro Tanaka   +14 more
doaj   +1 more source

Hepatocyte Nuclear Factor 1 and Hypertensive Nephropathy [PDF]

Hypertension, 2008
Hypertension in spontaneously hypertensive rat (SHR) is associated with renal redox stress, and we hypothesized that nephropathy arises in SHR-A3 from altered capacity to mitigate redox stress compared with nephropathy-resistant SHR lines. We measured renal expression of redox genes in distinct lines of the spontaneously hypertensive rat (SHR-A3, SHR ...
Renata I, Dmitrieva, Cruz A, Hinojos, Eric, Boerwinkle, Michael C, Braun, Myriam, Fornage, Peter A, Doris   +5 more
openaire   +2 more sources

Liver receptor homolog-1 (NR5A2) orchestrates hepatic inflammation and TNF-induced cell death

Cell Reports, 2023
Summary: The nuclear receptor liver receptor homolog-1 (LRH-1) has been shown to promote apoptosis resistance in various tissues and disease contexts; however, its role in liver cell death remains unexplored.
Rebekka Lambrecht, M. Eugenia Delgado, Vincent Gloe, Karina Schuetz, Anna Pia Plazzo, Barbara Franke, Truong San Phan, Jennifer Fleming, Olga Mayans, Thomas Brunner   +9 more
doaj   +1 more source

Hepatocyte Growth Factor-Dependent Antiviral Activity of Activated cdc42-Associated Kinase 1 Against Hepatitis B Virus

Frontiers in Microbiology, 2021
Activated cdc42-associated kinase 1 (ACK1) is a well-known non-receptor tyrosine kinase that regulates cell proliferation and growth through activation of cellular signaling pathways, including mitogen-activated protein kinase (MAPK).
Hye Won Lee, Yongwook Choi, Ah Ram Lee, Cheol-Hee Yoon, Kyun-Hwan Kim, Byeong-Sun Choi, Yong Kwang Park   +6 more
doaj   +1 more source

Hepatocyte nuclear factor 1β controls nephron tubular development [PDF]

Development, 2013
Nephron morphogenesis is a complex process that generates blood-filtration units (glomeruli) connected to extremely long and patterned tubular structures. Hepatocyte nuclear factor 1β (HNF1β) is a divergent homeobox transcription factor that is expressed in kidney from the first steps of nephrogenesis.
Massa, F., Garbay, S., Bouvier, R., Sugitani, Y., Noda, T., Gubler, M.-C., Heidet, L., Pontoglio, M., Fischer, E.   +8 more
openaire   +2 more sources