Results 241 to 250 of about 993,672 (387)

Supplementary Table 1 from Pancreatic Ductal Adenocarcinoma Subtyping Using the Biomarkers Hepatocyte Nuclear Factor-1A and Cytokeratin-81 Correlates with Outcome and Treatment Response [PDF]

, 2023
Alexander Muckenhuber, Anne Berger, Anna Melissa Schlitter, Katja Steiger, Björn Konukiewitz, Andreas Trumpp, Roland Eils, Jens Werner, Helmut Frieß, Iréne Esposito, Günter Klöppel, Güralp O. Ceyhan, Moritz Jesinghaus, Carsten Denkert, Marcus Bahra, Albrecht Stenzinger, Martin R. Sprick, Dirk Jäger, Christoph Springfeld, Wilko Weichert   +19 more
openalex   +1 more source

Hepatocyte Nuclear Factor 1 Inactivation Results in Hepatic Dysfunction, Phenylketonuria, and Renal Fanconi Syndrome

Cell, 1996
M. Pontoglio, J. Barra, M. Hadchouel, A. Doyen, C. Kress, Joséphine Poggi Bach, C. Babinet, M. Yaniv   +7 more
semanticscholar   +1 more source

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

Chemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves, Giulia Cristina de Andreoli Souza, Alvaro Jose Hernandez Tasco, Marcos José Salvador   +3 more
wiley   +1 more source

Induction of DNA synthesis in primary mouse hepatocytes is associated with nuclear pro-transforming growth factor and erbb-1 and is independent of c-jun [PDF]

, 2003
E. Schausberger, R. Eferl, W. Parzefall, M. Chabicovsky, P. Breit, E. F. Wagner, R. Schulte-Hermann, B. Grasl-Kraupp   +7 more
openalex   +1 more source

Supplementary Figure 1 from Hepatocyte Nuclear Factor-4α Promotes Gut Neoplasia in Mice and Protects against the Production of Reactive Oxygen Species [PDF]

, 2023
Mathieu Darsigny, Jean‐Philippe Babeu, Ernest G. Seidman, Fernand‐Pierre Gendron, Émile Lévy, Julie Carrier, Nathalie Perreault, François Boudreau   +7 more
openalex   +1 more source

Chemical Switching: A Concept Inspired by Strategies from Biocatalysis and Organocatalysis

ChemBioChem, EarlyView.
Chemical Switching is introduced as a novel technology that exploits the promiscuity of enzymatic transformations by applying small molecule organocatalytic switches (ORCAs) or gain‐of‐function protein variants. The modulation of underlying chemical principles thereby amplifies low‐rate or installs otherwise absent enzymatic activities to dominate ...
Torkild Visnes, Kaixin Zhou, Aurino M. Kemas, Dominic Campopiano, Volker M. Lauschke, Maurice Michel   +5 more
wiley   +1 more source

Genetic Study of Hepatocyte Nuclear Factor 1 Alpha Variants in Development of Early-Onset Diabetes Type 2 and Maturity-Onset Diabetes of the Young 3 in Iran. [PDF]

Adv Biomed Res, 2019
Mohammadi A, Eskandari A, Sarmadi A, Rahimi M, Iraj B, Hashemipour M, Chaleshtori MH, Tabatabaiefar MA.   +7 more
europepmc   +1 more source

Unveiling New Triazoloquinoxaline‐Based PROTACs Designed for the Selective Degradation of the ncBAF Chromatin Remodeling Subunit BRD9

Chemistry – A European Journal, EarlyView.
We present new BRD9‐targeting degraders featuring a chemical warhead and E3 ligase ligand that distinctly differ from the typical chemical units used for BRD9 degradation. Specifically, we identified two VHL‐based PROTACs (2 and 9) based on a [1,2,4]triazolo[4,3‐a]quinoxaline scaffold that effectively and selectively degrade BRD9 and exhibit ...
Martina Pierri, Guglielmo Bove, Erica Gazzillo, Ester Colarusso, Francesca Scala, Giacomo Pepe, Stefania Terracciano, Maria Giovanna Chini, Nicla Simonelli, Ines Bruno, Angela Nebbioso, Pietro Campiglia, Giuseppe Bifulco, Lucia Altucci, Nunzio Del Gaudio, Gianluigi Lauro   +15 more
wiley   +1 more source

Burer-Monteiro factorizability of nuclear norm regularized optimization [PDF]

arXiv
This paper studies the relationship between the nuclear norm-regularized minimization problem, which minimizes the sum of a $C^2$ function $h$ and a positive multiple of the nuclear norm, and its factorized problem obtained by the Burer-Monteiro technique.
arxiv