Results 201 to 210 of about 411,384 (307)

ScRNA-Seq Deciphers an Autocrine EFNA1-EPHA1 Loop That Reprograms the Microenvironment in Hepatocellular Carcinoma. [PDF]

J Hepatocell Carcinoma
Chen Y, Tang Y, Ning Y, Yang Y, Tian R, Mao Y, Feng Z, Lin W, Wang D, Feng X.   +9 more
europepmc   +1 more source

Hepatocyte [PDF]

, 2020
openaire   +1 more source

Comparison of Receptor‐Mediated Endocytosis and Its Application to Enhance DNA Transfection by TFAMoplex

Advanced NanoBiomed Research, EarlyView.
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer, Steffen Honrath, Jonas Kurmann, Alexander Klipp, Finn Brigger, Jean‐Christophe Leroux   +5 more
wiley   +1 more source

ITPR3 promotes liver fibrosis by damaging hepatocytes via the Ca2+/NF-B/LECT2 pathway. [PDF]

Sci Rep
Zhao X, Liu X, Ni M, Cao L, Zhao Y, Zhang J, Zhang H, Ye J.   +7 more
europepmc   +1 more source

Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue [PDF]

, 2016
et al,, Meganathan, Kesavan
core   +1 more source

The inhibitory effect of hepatic cancer energy metabolism on immune checkpoint therapy: perspectives from single-cell multi-omics analysis. [PDF]

Front Immunol
Li X, Tang L, Cao J, Liu Y.
europepmc   +1 more source

Molybdenum and cadmium co-induced apoptosis and necroptosis via activating endoplasmic reticulum stress and upregulating Caspase-8 expression in duck hepatocytes. [PDF]

Poult Sci
Xiao L, Nie G, Dai X, Li S, Wang S, Le X, Ren J, Zhang C.   +7 more
europepmc   +1 more source

Normalization of hepatic homeostasis in the Npc1nmf164 mouse model of Niemann-Pick type C disease treated with the histone deacetylase inhibitor vorinostat [PDF]

, 2017
al, et, Ory, Daniel S.
core   +1 more source

Comprehensive In Vitro Metabolic Characterization of Eudesmin in Human and Mouse Hepatocytes. [PDF]

Pharmaceutics
Lee MS, Kim JH, Song IS, Cho YY, Lee JY, Lee HS.   +5 more
europepmc   +1 more source

A Synergistic Inhibitor Development Strategy Against Human UDP‐Galactose‐4‐Epimerase

Angewandte Chemie International Edition, EarlyView.
The epimerase GalE is crucial for the biosynthesis of cancer‐relevant O‐GalNAc glycans. Here, we employ orthogonal, structurally enabled small molecule fragment screens to yield both covalent and non‐covalent inhibitors against GalE within no more than 22 elaborated compounds.
William M. Browne, Jonathan Pettinger, Teresa Weckwerth, Andrew Purkiss, Sing Hei Lok, Louisa Penicaut, Roksana Ogrodowicz, Raveena Prema, Simone Kunzelmann, Chloe Roustan, Ganka Bineva‐Todd, Saskia Pieters, Francesca Zappacosta, Alfred E. Doherty, Isobel Oram, Christelle Soudy, Robert Quinlan, Joanna Redmond, Svend Kjaer, David House, Stephane Mouilleron, Jacob T. Bush, Benjamin Schumann   +22 more
wiley   +1 more source