Results 1 to 10 of about 112,835 (346)

A Histopathological, Immunohistochemical and Biochemical Investigation on the in vitro Antioxidant, Myeloprotective, Hematoprotective and Hepatoprotective Effects of Hypericum triquetrifolium Seed Extract Against Cyclophosphamide-Induced Toxicity [PDF]

Brazilian Archives of Biology and Technology, 2019
The aim of this study was to investigate in vitro antioxidant properties and in vivo protective effects of the methanol extract of the Hypericum triquetrifolium Turra (HT) seed against acute hepatotoxicity, myelotoxicity and hematotoxicity in rats ...
Songul Cetik Yildiz, Cumali Keskin, Varol Sahintürk, Adnan Ayhanci   +3 more
doaj   +2 more sources

Hepatoprotective effect of sitagliptin against methotrexate induced liver toxicity

PLoS ONE, 2017
Sitagliptin is selective dipeptidyl peptidase-4 inhibitor (DPP4-I), used clinically as a new oral anti-diabetic agent. This study explored the underlying mechanisms of the hepatoprotective role of sitagliptin pretreatment against methotrexate (MTX ...
Hany M. Abo‐Haded, Mohamed A. Elkablawy, Zeyad Al-johani, Osama Al-ahmadi, Dina S. El‐Agamy   +4 more
openalex   +3 more sources

Characterization of Polysaccharides with Antioxidant and Hepatoprotective Activities from the Edible Mushroom Oudemansiella radicata

Molecules, 2017
The preliminary structure, in vitro antioxidant and in vivo hepatoprotective activities of water-soluble polysaccharides (ORWP) and alkali-soluble polysaccharides (ORAP), prepared from the mushroom Oudemansiella radicata, were investigated. Both ORWP and
Qin Liu, Mengjuan Zhu, Xueran Geng, Hexiang Wang, Tzi Bun Ng   +4 more
doaj   +2 more sources

Hepatitis C: From inflammatory pathogenesis to anti-inflammatory/hepatoprotective therapy [PDF]

World Journal of Gastroenterology, 2018
Hepatitis C virus (HCV) infection commonly causes progressive liver diseases that deteriorate from chronic inflammation to fibrosis, cirrhosis and even to hepatocellular carcinoma.
Huang, Meng-Hao, Jiang, Jian-Dong, Li, Hu, Peng, Zong-Gen   +3 more
core   +3 more sources

Promising hepatoprotective agents from the natural sources: a study of scientific evidence

Egyptian Liver Journal, 2023
Background Natural bioactive components derived from plant secondary metabolites have been pronounced as valuable alternatives for anticipating and subsiding hepatotoxic effects and its chronic complications based on experimental verification.
Bipindra Pandey, R. Baral, Atisammodavardhana Kaundinnyayana, Sushil Panta   +3 more
semanticscholar   +1 more source

Ethnomedicinal Plants Traditionally Used for the Treatment of Jaundice (Icterus) in Himachal Pradesh in Western Himalaya—A Review

Plants, 2021
Ethnomedicinal plants have a significant role in the lives of people of rural and tribal areas. Thousands of medicinal plant species are used to treat various diseases, including jaundice, and are considered an important therapeutic resource to minimize ...
Disha Raghuvanshi, Rajni Dhalaria, Anjali Sharma, Dinesh Kumar, Harsh Kumar, Martin Valis, Kamil Kuča, Rachna Verma, Sunil Puri   +8 more
doaj   +1 more source

Hepatoprotective Effect of Kaempferol: A Review of the Dietary Sources, Bioavailability, Mechanisms of Action, and Safety

Advances in pharmacological and pharmaceutical sciences, 2023
The liver is the body's most critical organ that performs vital functions. Hepatic disorders can affect the physiological and biochemical functions of the body.
Maulana Yusuf Alkandahri, B. Pamungkas, Zulpakor Oktoba, Mareetha Zahra Shafirany, Lela Sulastri, Maya Arfania, E. N. Anggraeny, Ade Pratiwi, Fitri Dwi Astuti, Indriyani, Siti Yuliani Dewi, Salsa Zulfa Hamidah   +11 more
semanticscholar   +1 more source

A Comprehensive Review of the Pharmacological Importance of Dietary Flavonoids as Hepatoprotective Agents

Evidence-Based Complementary and Alternative Medicine, 2023
The liver is a crucial organ that is involved in various kinds of metabolic activity and a very stable accessory gland for the digestive system. Long-term or persistent inflammation and oxidative stress due to any reasons have a substantial impact on the
Gajender, A. Mazumder, Ashwani Sharma, Md A K Azad   +3 more
semanticscholar   +1 more source

Phytosomes as a Plausible Nano-Delivery System for Enhanced Oral Bioavailability and Improved Hepatoprotective Activity of Silymarin

Pharmaceuticals, 2022
Silymarin, a phyto-constituent derived from the plant Silybum marianum, has been widely acknowledged for its hepatoprotective activities. Nevertheless, its clinical utility is adversely hampered by its poor water-solubility and its limited oral ...
R. G. Shriram, A. Moin, H. F. Alotaibi, El-Sayed Khafagy, Ahmed Al Saqr, A. S. Abu Lila, R. N. Charyulu   +6 more
semanticscholar   +1 more source

Hepatoprotective mechanism of Silybum marianum on nonalcoholic fatty liver disease based on network pharmacology and experimental verification

Bioengineered, 2022
The study aimed to identify the key active components in Silybum marianum (S. marianum) and determine how they protect against nonalcoholic fatty liver disease (NAFLD).
Guoyan Jiang, Chunhong Sun, Xiaodong Wang, Jie Mei, Chen Li, Honghong Zhan, Yi-Xuan Liao, Yong-xing Zhu, Jingxin Mao   +8 more
semanticscholar   +1 more source