Results 121 to 130 of about 112,835 (346)

Protective Effects of Baccharis dracunculifolia Leaves Extract against Carbon Tetrachloride- and Acetaminophen-Induced Hepatotoxicity in Experimental Animals

Molecules, 2014
In this work we investigated the in vivo protective effects of Baccharis dracunculifolia leaves extract (BdE) against carbon tetrachloride (CCl4)- and acetaminophen (APAP)-induced hepatotoxicity.
Túlio P. Rezende, José Otávio do A. Corrêa, Beatriz J. V. Aarestrup, Fernando M. Aarestrup, Orlando V. de Sousa, Ademar A. da Silva Filho   +5 more
doaj   +1 more source

Phenolic compounds protect HepG2 cells from oxidative damage : relevance of glutathione levels [PDF]

, 2006
Prova tipográfica (In Press)In the present work, the potential hepatoprotective effects of five phenolic compounds were evaluated against oxidative damages induced by tert-butyl hydroperoxide (t-BHP) in HepG2 cells in order to relate in vitro antioxidant
Ferreira, Manuel Fernandes, Lima, Cristóvão F., Wilson, Cristina Pereira   +2 more
core   +1 more source

Hepatoprotective effects of blue honeysuckle on CCl4‐induced acute liver damaged mice

Food Science & Nutrition, 2018
The objective of this study was to evaluate the hepatoprotective effects of blue honeysuckle (BH) on carbon tetrachloride (CCl4)‐induced acute hepatic damage in mice. The experiment used a total of 60 ICR mice, which were divided into six groups.
You-Suk Lee, I. Cho, J. Kim, Min-Ki Lee, S. Ku, Jae‐Suk Choi, Hae-Jeung Lee   +6 more
semanticscholar   +1 more source

Interpretable machine learning enables early and accurate detection of drug‐induced liver injury: A multicenter study with real‐world clinical translation

Interdisciplinary Medicine, EarlyView.
This study develops an interpretable gradient‐boosting model that accurately identifies drug‐induced liver injury (DILI) using routine laboratory data. The model explains key clinical features through SHapley Additive exPlanations analysis and detects DILI earlier than expert evaluation, offering a transparent and practical tool for precision ...
Jingyi Ling, Shian Zhang, Jun Lin, Zhengju Xu, Runcheng Xu, Qian Lv, Kaixiang Zhang, Sheng Liu, Jie Guo, Cheng Hua, Yin Jia, Xiaoyu Xu, Kun Qian, Shanrong Liu   +13 more
wiley   +1 more source

Review of plants with hepatoprotective activity evaluated in Mexico [PDF]

, 2014
Liver diseases represent a major health problem around the world. in Mexico these are the 5th leading cause of death in the economically active population.
Cordero Pérez, Paula, Muñoz Espinosa, Linda Elsa, Pérez Meseguer, Jonathan, Salazar Aranda, Ricardo, Torres González, Liliana, Waksman de Torres, Noemí   +5 more
core  

A Biomedical Investigation of the Hepatoprotective Effect of Radix salviae miltiorrhizae and Network Pharmacology-Based Prediction of the Active Compounds and Molecular Targets

International Journal of Molecular Sciences, 2017
Radix salviae miltiorrhizae (Danshen in Chinese), a classic traditional Chinese medicine (TCM) herb, has been used for centuries to treat liver diseases.
M. Hong, Sha Li, Ning Wang, H. Tan, F. Cheung, Yibin Feng   +5 more
semanticscholar   +1 more source

Interferon‐gamma blocking as a promising treatment for severe liver dysfunction in secondary hemophagocytic lymphohistiocytosis after liver transplantation

JPGN Reports, EarlyView.
Abstract Hemophagocytic lymphohistiocytosis (HLH) is a life‐threatening hyperinflammatory syndrome that can occur after solid organ transplantation but remains underrecognized in this setting. The diagnosis is often delayed due to overlapping clinical manifestations with infection, rejection, or malignancy, and management becomes particularly ...
Chen Chen, Tao Zhou, Jing Jin, Yi Luo, Lijing Shen, Qiang Xia, Yongbing Qian   +6 more
wiley   +1 more source

Hepatoprotective effect of Chichorium intybus L. on liver toxicity in rat

Journal of Medicinal Plants, 2006
Background: Plant phenolic compounds such as flavonoids have important role in treatment of many diseases. Also some of them have potent hepatoprotective effects.
H Madani, S Asgary, GH Naderi, M Talebolhoseini   +3 more
doaj  

Aronia melanocarpa (Michaux) Elliot Fruit Juice Attenuates Acetaminophen-induced Hepatotoxicity on Larval Zebrafish Model

Journal of Agricultural Sciences
Aronia melanocarpa (Michaux) Elliot (chokeberry) is a natural medicinal plant with a rich content of phenolic compounds such as procyanidins, anthocyanins, and phenolic acids.
Gülçin Çakan Akdoğan, Çiğdem Bilgi
doaj   +1 more source

Hepatoprotective and Renoprotective Properties of Lovastatin-Loaded Ginger and Garlic Oil Nanoemulsomes: Insights into Serum Biological Parameters

Medicina, 2019
Background and Objectives: Dyslipidemia is gaining much attention among healthcare professionals because of its high association with the malfunctioning of a number of normal physiological and metabolic processes in the body.
Syed Ali Faran, Sajid Asghar, Syed Haroon Khalid, Ikram Ullah Khan, Muhammad Asif, Ikrima Khalid, Umar Farooq Gohar, Tanveer Hussain   +7 more
doaj   +1 more source