Results 241 to 250 of about 56,507 (292)

Study of Hepatoprotective Effects of Xymedon

Bulletin of Experimental Biology and Medicine, 2013
Xymedon (1-(β-oxyethyl)-4,6-dimethyl-1,2-dihydro-2-oxopyrimidine), a regeneratory and wound-healing drug, exhibited hepatoprotective activity in laboratory animals with experimental toxic hepatitis. Oral drug reduced the severity of toxic involvement of the liver induced by CCl4 and reduced animal mortality.
Vyshtakalyuk A., Nazarov N., Zueva I., Lantsova A., Minnekhanova O., Busygin D., Porfiryev A., Evtyugin V., Reznik V., Zobov V.   +9 more
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Present status of hepatoprotectants

1999
Perpetual exposure of liver to xenobiotics and therapeutic agents leads to toxic manifestations of a complex and diverse nature. Not a single curative therapeutic agent has been found so far which could provide lasting remedy to patients suffering from hepatic disorders.
V J, Ram, A, Goel
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Hepatoprotective functions of jujuboside B

Journal of Natural Medicines, 2022
Jujuboside B (JB) found in the seeds of Zizyphi Spinosi Semen possesses pharmacological functions, such as anti-inflammatory, antiplatelet aggregation, and antianxiety potentials. This study evaluated the effect of JB on liver failure in cecal ligation and puncture (CLP)-induced sepsis.
Chaeyeong Kim, Yun Hee Jeong, Nayeon Kim, Soo Ho Ryu, Jong-Sup Bae   +4 more
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Evaluation of hepatoprotective activity of Legumes

Phytomedicine, 2001
Mung bean, adzuki bean, black bean and rice bean are foods and folk medicines of Taiwan. We evaluated the effects of various water extract concentrations (100, 500 and 1000 mg/kg body wt.) and silymarin (25 mg/kg body wt. on acetaminophen-induced liver injury by measuring serum glutamate-oxalate-transaminase (sGOT) and serum glutamate-pyruvate ...
S J, Wu, J S, Wang, C C, Lin, C H, Chang
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Hepatoprotective effect of sesquiterpenes in turmeric

BioFactors, 2004
AbstractHepatoprotective effect of turmeric together with its sesquiterpenes and curcuminoids fractions were examined on D‐galactosamine induced liver injury in rats. All the diets individually contained the turmeric extract, the curcuminoids fraction, and the sesquiterpenes fraction suppressed the increase of LDH, ALT, and AST levels caused by D‐GalN ...
Masazumi, Miyakoshi, Yasunaga, Yamaguchi, Ryoji, Takagaki, Kenji, Mizutani, Toshimitsu, Kambara, Takao, Ikeda, M S, Zaman, Hiroki, Kakihara, Asako, Takenaka, Kiharu, Igarashi   +9 more
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Hepatoprotective effects of Astraglus root

Journal of Ethnopharmacology, 1990
Oral administration of an ethanol extract of the root of Astragalus membranaceus alleviated liver injury induced by stilbenemidine. Pre-administration in mice reduced elevated SGPT levels and subacute toxicity of stilbenemidine, decreased pentobarbital-induced loss of righting reflex and protected hepatic cells from pathological changes.
Z L, Zhang, Q Z, Wen, C X, Liu
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Hepatoprotective Ayurvedic plants – a review

Journal of Complementary and Integrative Medicine, 2016
Abstract The liver plays vital functions in the maintenance and performance of the body. Most of the metabolic and physiological processes of our body as well as the detoxification of various drugs and xenobiotic chemicals occur in the liver.
Anupama R, Valvi, Neelam, Mouriya, Rajani B, Athawale, Narendra S, Bhatt   +3 more
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An Overview of Hepatoprotective Effects of Thymoquinone

Recent Patents on Food, Nutrition & Agriculture, 2018
Liver diseases are globally recognized as major medical problems. Several species of herbal medicine have been investigated for the management of liver-related diseases.In this context, Thymoquinone (TQ) as the main constituent of Nigella sativa has long been focused for the treatment of liver diseases in recent years. To suppressing liver diseases, it
Mohammad-Foad, Noorbakhsh, Farzad, Hayati, Saeed, Samarghandian, Hanieh, Shaterzadeh-Yazdi, Tahereh, Farkhondeh   +4 more
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Hepatoprotective effects of Wedelia calendulacea

Journal of Ethnopharmacology, 1989
The alcoholic extract of whole plant Wedelia calendulacea exhibited protective activity against carbon tetrachloride-induced liver injury in vivo. The extract also increased the bile flow in rats suggesting a stimulation of liver secretory capacity. The minimum lethal dose was greater than 200 mg/kg p.o. in mice.
A K, Sharma, K K, Anand, P, Pushpangadan, B K, Chandan, C L, Chopra, Y S, Prabhakar, N P, Damodaran   +6 more
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Mechanisms of Hepatoprotection by Nitric Oxide

Annals of the New York Academy of Sciences, 2002
Abstract:Nitric oxide (NO) exerts numerous antiapoptotic effects on hepatocytes in settings of inflammation and tissue damage. These actions of NO are modulated by a variety of mechanisms under both physiologic and pathologic conditions. Nitric oxide inhibits cell death or apoptosis by modulation of heat shock proteins,S‐nitrosylation of caspases at ...
Yinna, Wang, Yoram, Vodovotz, Peter K M, Kim, Ruben, Zamora, Timothy R, Billiar   +4 more
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