Increased hepatotoxicity among HIV-infected adults co-infected with Schistosoma mansoni in Tanzania: A cross-sectional study. [PDF]
Little is known about hepatotoxicity in patients with schistosome and HIV co-infections. Several studies have reported increased liver enzymes and bilirubin levels associated with schistosome infection.
Amon I Marti +8 more
doaj +1 more source
Alectinib is a key drug for treating anaplastic lymphoma kinase (ALK)-positive non-small-cell lung cancer (NSCLC). Alectinib-induced hepatotoxicity is less common than that through other ALK inhibitors, such as crizotinib or ceritinib.
Go Makimoto +4 more
doaj +1 more source
Navigating liver cancer with mouse models: a comprehensive overview of HCC experimental systems [PDF]
Hepatocellular carcinoma (HCC) is the most prevalent primary hepatic malignancy and is globally the third leading cause of cancerrelated deaths. Despite significant advancements in diagnostic techniques and therapeutic interventions, HCC prognosis ...
Ga-Young Kim +4 more
doaj +1 more source
Cyclosporin a hepatotoxicity in 66 renal allograft recipients [PDF]
Liver functional abnormalities were seen in 13 (19.7%) of 66 recipients of cadaveric renal homografts treated with cyclosporin A and prednisone. However, such presumed hepatotoxicity was a minor problem in the use of cyclosporin A.
Iwatsuki, S, Klintmalm, GBG, Starzl, TE
core +1 more source
Studies on hepatotoxicity induced by chlorinated hydrocarbons. II. Lipid metabolism and absorption spectrum of microsomal lipid in the mice exposed to 1, 1, 2, 2-tetrachloroethane [PDF]
Female Cb mice weighing 20-23 g were exposed to 800 ppm (in average) of 1, I, 2, 2.tetrachloroethane for 3 hours. Both triglyceride and phospholipid in the liver and plasma were determined at varying times after the exposure.
Tomokuni, Katsumaro
core +1 more source
Assessment of Risk Factors of Hepatotoxicity among Tuberculosis Patients
Tuberculosis is a devastating disease caused by Mycobacterium tuberculosis. If left untreated or not properly treated, it could lead to progressive tissue damage and even death. Short-term chemotherapy containing isoniazid, rifampicin.
Muhammad F. Wardhana +2 more
doaj +1 more source
A four-month gatifloxacin-containing regimen for treating tuberculosis. [PDF]
BACKGROUND: Shortening the course of treatment for tuberculosis would be a major improvement for case management and disease control. This phase 3 trial assessed the efficacy and safety of a 4-month gatifloxacin-containing regimen for treating rifampin ...
Amukoye, Evans +19 more
core +1 more source
Background Rheumatoid arhtirtis (RA) is a chronic autoimmune disease that mainly attacks joints. It may causes joint deformities which leads to lower quality of life of RA patients.
Rahma Anindya Prathitasari +1 more
doaj +1 more source
Effects of Enzyme Induction and/or Glutathione Depletion on Methimazole Induced Hepatotoxicity in Mice and the Protective Role of N-Acetylcysteine [PDF]
Purpose: Methimazole is the most convenient drug used in the management of hyperthyroid patients. However, associated with its clinical use is hepatotoxicity as a life threatening adverse effect.
Reza Heidari +3 more
doaj +1 more source
Hepatitis induced by noni juice from Morinda citrifolia: A rare cause of hepatotoxicity or the tip of the iceberg? [PDF]
A 24-year-old female patient presented to her community hospital with mild elevations of serum transaminase and bilirubin levels. Because of multiple sclerosis, she was treated with interferon beta-la for 6 weeks.
Diebold, J. +3 more
core +1 more source

