Results 291 to 300 of about 137,616 (341)
Some of the next articles are maybe not open access.
Drug Intelligence & Clinical Pharmacy, 1985
An adolescent male with chronic schizophrenic disorder, paranoid type, was treated with molindone. He developed hepatotoxicity in the early treatment phase as evidenced by flu-like symptoms and laboratory abnormalities of liver functions. These symptoms and his hepatic functions improved on discontinuing molindone.
Lawrence E. Banta +2 more
openaire +3 more sources
An adolescent male with chronic schizophrenic disorder, paranoid type, was treated with molindone. He developed hepatotoxicity in the early treatment phase as evidenced by flu-like symptoms and laboratory abnormalities of liver functions. These symptoms and his hepatic functions improved on discontinuing molindone.
Lawrence E. Banta +2 more
openaire +3 more sources
Hepatotoxicity of Chemotherapy
Seminars in Oncology, 2006The selection of an antineoplastic regimen for an oncology patient is based first on the availability of effective drugs and then on a balancing of potential treatment-related toxicities with the patient's clinical condition and associated comorbidities. Liver function abnormalities are commonly observed in this patient population and identifying their
Michael C. Perry +3 more
openaire +3 more sources
Extracellular vesicles induce minimal hepatotoxicity and immunogenicity.
Nanoscale, 2019Extracellular vesicles (EVs) mediate cellular communication through the transfer of active biomolecules, raising interest in using them as biological delivery vehicles for therapeutic drugs.
Amer F. Saleh +17 more
semanticscholar +1 more source
Analytical Chemistry, 2019
Drug-induced hepatotoxicity represents an important challenge for safety in drug development. The production of peroxynitrite (ONOO-) is proposed as an early sign in the progression of drug-induced hepatotoxicity.
Dandan Li +7 more
semanticscholar +1 more source
Drug-induced hepatotoxicity represents an important challenge for safety in drug development. The production of peroxynitrite (ONOO-) is proposed as an early sign in the progression of drug-induced hepatotoxicity.
Dandan Li +7 more
semanticscholar +1 more source
Gastroenterology, 1980
This review of acetaminophen hepatotoxicity begins with a history of the drug and consideration of the scope of its current use. The molecular basis for hepatotoxicity is discussed and this serves as a background for delineation of its clinical manifestations and treatment.
openaire +3 more sources
This review of acetaminophen hepatotoxicity begins with a history of the drug and consideration of the scope of its current use. The molecular basis for hepatotoxicity is discussed and this serves as a background for delineation of its clinical manifestations and treatment.
openaire +3 more sources
Hepatotoxicity of thiazolidinediones
Expert Opinion on Drug Safety, 2003Thiazolidinediones are insulin sensitisers now widely used for the treatment of Type 2 diabetes mellitus. The initial marketed drug in this class, troglitazone, was removed from the market worldwide after approximately 3 years of use due to rare but severe hepatotoxicity, which sometimes resulted in liver failure leading to the need for liver ...
openaire +3 more sources
Herb-Drug Interactions and Hepatotoxicity.
Current drug metabolism, 2019BACKGROUND In recent times, herbals or phytomedicines have become very popular due to their global acceptance as a complementary and alternative remedy. While modern drugs are commercially available only after laboratory validations, clinical trials, as ...
M. Parvez, V. Rishi
semanticscholar +1 more source
Hepatotoxicity of Antidepressants
International Clinical Psychopharmacology, 1991Detection of abnormal liver function tests in a patient receiving an antidepressant or other psychopharmacological agent presents a major problem to the clinician, who must decide whether or not to withdraw a drug which may be of central importance in the patient's management.
openaire +3 more sources
Southern Medical Journal, 2000
We report a case of hepatotoxicity in a 2-month-old baby after a camphor-containing cold remedy was applied dermally. Liver function tests returned to normal after the application of the cold remedy was discontinued. Ingestion of camphor can cause severe liver and central nervous system injury, and neurotoxicity has been observed after exposure to ...
A, Uc, W P, Bishop, K D, Sanders
openaire +2 more sources
We report a case of hepatotoxicity in a 2-month-old baby after a camphor-containing cold remedy was applied dermally. Liver function tests returned to normal after the application of the cold remedy was discontinued. Ingestion of camphor can cause severe liver and central nervous system injury, and neurotoxicity has been observed after exposure to ...
A, Uc, W P, Bishop, K D, Sanders
openaire +2 more sources
IEEE/ACM Transactions on Computational Biology & Bioinformatics, 2019
Drug-induced hepatotoxicity may cause acute and chronic liver disease, leading to great concern for patient safety. It is also one of the main reasons for drug withdrawal from the market.
R. Su +4 more
semanticscholar +1 more source
Drug-induced hepatotoxicity may cause acute and chronic liver disease, leading to great concern for patient safety. It is also one of the main reasons for drug withdrawal from the market.
R. Su +4 more
semanticscholar +1 more source