Results 291 to 300 of about 146,077 (348)

Prediction and analysis of toxic and side effects of tigecycline based on deep learning. [PDF]

Front Microbiol
Xiong Y, Liu G, Tang X, Xia B, Yu Y, Fan G.   +5 more
europepmc   +1 more source

Management of Mycobacterium ulcerans infection (Buruli ulcer) in Australia: consensus statement

Medical Journal of Australia, EarlyView.
Abstract Introduction Buruli ulcer, caused by Mycobacterium ulcerans, is increasing in incidence and spreading to new areas in southeast Australia. With increasing experience and emerging evidence, this consensus statement considers contemporary data to provide up‐to‐date recommendations to clinicians who may encounter this disease.
Stephen Muhi, Victoria RV Cox, Matthew O'Brien, Jonathan T Priestley, Jodie Hill, Adrian Murrie, Anthony McDonald, Peter Callan, Grant A Jenkin, N Deborah Friedman, Kasha P Singh, Callum Maggs, Peter Kelley, Eugene Athan, Paul DR Johnson, Daniel P O'Brien   +15 more
wiley   +1 more source

<i>Dichrocephala integrifolia</i> (L.f.) Kuntze Leaf Aqueous Extract Improves Liver Architecture in a Model of Aflatoxin-Containing Peanut-Induced Hepatotoxicity in Wistar Rats. [PDF]

J Toxicol
Mbatchou A, Ngueguim Tsofack F, Donfack JH, Kamkumo Gounoue R, Mbock MA, Tientcheu Djientcheu JP, Gamo Zemo F, Fifen RN, Djomeni Dzeufiet PD, Dimo T.   +9 more
europepmc   +1 more source

Treatment Landscape in Pediatric Immune Thrombocytopenia: Addressing Unmet Needs

Pediatric Blood &Cancer, Volume 72, Issue 7, July 2025.
ABSTRACT Pediatric immune thrombocytopenia (ITP) is associated with a multifaceted burden on children and their parents/caregivers due to bleeding, fatigue, activity restrictions, and psychological distress. Most children recover within 12 months, but up to 30% develop chronic ITP.
Joana Azevedo, Jennifer DiRaimo, Cindy Neunert, Nichola Cooper, Rachael F. Grace   +4 more
wiley   +1 more source

Mitigating doxorubicin-induced hepatotoxicity in male rats: The role of aerobic interval training and curcumin supplementation in reducing oxidative stress, endoplasmic reticulum stress and apoptosis. [PDF]

Sci Rep
Zobeydi AM, Mousavi Namavar SN, Sadeghi Shahdani M, Choobineh S, Kordi MR, Rakhshan K.   +5 more
europepmc   +1 more source

Multifaceted Role of Microbiota‐Derived Indole‐3‐Acetic Acid in Human Diseases and Its Potential Clinical Application

The FASEB Journal, Volume 39, Issue 11, 15 June 2025.
The complexity of indole‐3‐acetic acid's (IAA's) role in human health and disease. IAA is a multifaceted compound with significant consequences for several physiological and pathological processes. ABSTRACT Indole‐3‐acetic acid (IAA) is recognized as a common plant growth hormone.
Nargis Shaheen, Jiaxing Miao, Boyu Xia, Yutong Zhao, Jing Zhao   +4 more
wiley   +1 more source

Incidence of antibody-drug conjugate-related hepatotoxicity in breast cancer: a systematic review and meta-analysis. [PDF]

Ther Adv Drug Saf
Yang P, Zhang H, Li J, Li Z, Liu Z, Wang M, Zhao F, Zhao J, Shen G, Zhao Y.   +9 more
europepmc   +1 more source

Daphnetin alleviates inflammation and promotes autophagy via the AMPK/mTOR pathway in gouty arthritis

Journal of Cell Communication and Signaling, Volume 19, Issue 2, June 2025.
Daphnetin, a coumarin derivative, regulates the AMPK/mTOR signaling pathway to inhibit inflammation and promote autophagy in monosodium urate‐induced mice and THP‐1 cells, thereby suppressing MSU‐induced gouty arthritis. Abstract Gouty arthritis (GA) is an inflammatory disease resulting from monosodium urate (MSU) crystal deposition in joints and ...
Zhiyong Liu, Aichun Chu, Zhiqian Bai, Chao Yang   +3 more
wiley   +1 more source

Hepatotoxicity Score: A New Method to Adjust for Use of Potentially Hepatotoxic Medications by Chronic Liver Disease Status. [PDF]

Pharmacoepidemiol Drug Saf
Lo Re V, Newcomb CW, Carbonari DM, Mezochow AK, Hennessy S, Rentsch CT, Park LS, Tate JP, Bräu N, Bhattacharya D, Lim JK, Mezzacappa C, Njei B, Roy JA, Taddei TH, Justice AC, Torgersen J.   +16 more
europepmc   +1 more source

Comparison of Neoadjuvant Chemotherapy With FLOT and Modified DCF Regimens in Nonmetastatic Gastric Adenocarcinoma

Cancer Reports, Volume 8, Issue 6, June 2025.
ABSTRACT Backgrounds Gastric adenocarcinoma is a common and severe type of malignancy. Treatment for advanced cases involves neoadjuvant chemotherapy before surgery and adjuvant chemotherapy if needed. Aims In this study, a comparison of two regimens of FLOT and mDCF has been conducted with regard to pathological and radiological response, as well as ...
Mehdi Pourghasemian, Maryam Salimi, Effat Iranijam, Mohammad Negaresh   +3 more
wiley   +1 more source