Results 31 to 40 of about 137,616 (341)
Journal of the American Chemical Society, 2019 Near-infrared (NIR) fluorescence imaging technique is garnering increasing research attention due to various advantages. However, most NIR fluorescent probes still suffer from a false signals problem owing to their instability in real application ...
Dan Cheng +7 more
semanticscholar +1 more source
BMC Gastroenterology, 2022 Background Hepatotoxicity due to highly active antiretroviral therapy (HAART) has gained prominent attention since it can be affected by many factors.
Lem Edith Abongwa +13 more
doaj +1 more source
Hepatotoxicity of immune checkpoint inhibitors: a Bayesian network meta-analysis
Hepatology Communications, 2023 Background:. This systematic review and network meta-analysis aimed to provide a complete hepatotoxicity profile, hepatotoxicity spectrum, and safety ranking of immune checkpoint inhibitor drugs for cancer treatment. Methods:.
Caiyun Zheng +7 more
doaj +1 more source
Molecules, 2022 Fraxinellone (FRA), a major active component from Cortex Dictamni, produces hepatotoxicity via the metabolization of furan rings by CYP450. However, the mechanism underlying the hepatotoxicity of FRA remains unclear.
Shuting Wang +11 more
doaj +1 more source
Cellular Physiology and Biochemistry, 2017 Background/Aims: Clinical reports on adverse reactions that result from Polygonum multiflorum (PM) and its preparations, especially regarding liver injury, have recently received widespread attention.
Longfei Lin +7 more
doaj +1 more source
Anti-tuberculosis drug induced hepatotoxicity among TB/HIV co-infected patients at Jimma University Hospital, Ethiopia: nested case-control study. [PDF]
PLoS ONE, 2013 This study was carried out to determine the incidence and predictors of anti-tuberculosis drug induced hepatotoxicity among TB/HIV co-infected patients at Jimma University Hospital, Ethiopia.A nested case-control study was conducted by reviewing charts ...
Alima Hassen Ali +3 more
doaj +1 more source
Hepatotoxicity of botanicals [PDF]
Public Health Nutrition, 2000 AbstractObjectiveHepatic impairment resulting from the use of conventional drugs is widely acknowledged, but there is less awareness of the potential hepatotoxicity of herbal preparations and other botanicals, many of which are believed to be harmless and are commonly used for self-medication without supervision. The aim of this paper is to examine the
Felix Stickel +2 more
openaire +2 more sources
Selection of GalNAc-conjugated siRNAs with limited off-target-driven rat hepatotoxicity
Nature Communications, 2018 Small interfering RNAs (siRNAs) conjugated to a trivalent N-acetylgalactosamine (GalNAc) ligand are being evaluated in investigational clinical studies for a variety of indications.
Maja M. Janas +14 more
semanticscholar +1 more source
Seminars in liver disease (Print), 2019 Acetaminophen (APAP) is one of the most popular and safe pain medications worldwide. However, due to its wide availability, it is frequently implicated in intentional or unintentional overdoses where it can cause severe liver injury and even acute liver ...
A. Ramachandran, H. Jaeschke
semanticscholar +1 more source
Hepatotoxicity of a Cannabidiol-Rich Cannabis Extract in the Mouse Model
Molecules, 2019 The goal of this study was to investigate Cannabidiol (CBD) hepatotoxicity in 8-week-old male B6C3F1 mice. Animals were gavaged with either 0, 246, 738, or 2460 mg/kg of CBD (acute toxicity, 24 h) or with daily doses of 0, 61.5, 184.5, or 615 mg/kg for ...
Laura E. Ewing +8 more
semanticscholar +1 more source