Results 11 to 20 of about 6,675 (181)
Bacteria homologus to Aeromonas capable of microcystin degradation [PDF]
, 2014 Water blooms dominated by cyanobacteria are capable of producing hepatotoxins known as microcystins. These toxins are dangerous to people and to the environment. Therefore, for a better understanding of the biological termination of this increasingly
Dziadek, J. +5 more
core +1 more source
Marine Drugs, 2019 Microcystins are a family of chemically diverse hepatotoxins produced by distantly related cyanobacteria and are potent inhibitors of eukaryotic protein phosphatases 1 and 2A.
Tânia Keiko Shishido +7 more
doaj +1 more source
Impaired liver regeneration and lipid homeostasis in CCl4 treated WDR13 deficient mice
Laboratory Animal Research, 2020 WDR13 - a WD repeat protein, is abundant in pancreas, liver, ovary and testis. Absence of this protein in mice has been seen to be associated with pancreatic β-cell proliferation, hyperinsulinemia and age dependent mild obesity.
Arun Prakash Mishra +4 more
doaj +1 more source
Toxins, 2013 Cyanobacteria (also called blue-green algae) are ubiquitous in aquatic environments. Some species produce potent toxins that can sicken or kill people, domestic animals, and wildlife.
Tegwin K. Taylor +4 more
doaj +1 more source
Proteomic identification of IPSE/alpha-1 as a major hepatotoxin secreted by Schistosoma mansoni eggs. [PDF]
PLoS Neglected Tropical Diseases, 2011 Eggs deposited in the liver of the mammalian host by the blood fluke parasite, Schistosoma mansoni, normally drive a T-helper-2 (Th2)-mediated granulomatous response in immune-competent mice.
Maha-Hamadien Abdulla +3 more
doaj +1 more source
Studies of liver phosphorylase in hepatic injuries. I. Alteration in enzyme activity [PDF]
, 1978 Phosphorylase activities (total and a form) were determined in the livers of experimental hepatic injuries with carbon tetrachloride or galactosamine and the livers of patients with liver diseases.
Kobayashi, Michio
core +1 more source
1,1-Dichloroethylene: An Apoptotic Hepatotoxin? [PDF]
Environmental Health Perspectives, 1984 Within 2 hr after 1,1-dichloroethylene administration, the following phenomena occur in livers of fasted rats: dilation and disruption of bile canaliculi, plasma membrane invagination and loss of microvilli, cytoplasmic vacuolation, and loss of density in mitochondrial matrices.
E S, Reynolds +3 more
openaire +3 more sources
Toxins, 2013 A two and a half year old spayed female Miniature Australian Shepherd presented to a Montana veterinary clinic with acute onset of anorexia, vomiting and depression. Two days prior, the dog was exposed to an algal bloom in a community lake. Within h, the
Michael J. Murray +5 more
doaj +1 more source
Hepatotoxin-induced changes in the adult murine liver promote MYC-induced tumorigenesis. [PDF]
PLoS ONE, 2008 Overexpression of the human c-MYC (MYC) oncogene is one of the most frequently implicated events in the pathogenesis of hepatocellular carcinoma (HCC).
Shelly Beer +5 more
doaj +1 more source
Marine Drugs, 2019 Microcystins are cyclic heptapeptides from cyanobacteria that are potent inhibitors of protein phosphatases and are toxic to animals and humans. At present, more than 250 microcystin variants are known, with variants reported for all seven peptide ...
Vittoria Mallia +4 more
doaj +1 more source