Results 241 to 250 of about 4,105 (286)
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Detection of the cyanobacterial hepatotoxins microcystins
Toxicology and Applied Pharmacology, 2005Concern regarding the presence of microcystins in drinking water and their possible contamination in food (e.g., salad vegetables, fish, shellfish) has resulted in the need for reliable methods for the detection and accurate quantification of this class of toxins.
Jacqui, McElhiney, Linda A, Lawton
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Investigations into a Hepatotoxin in Lupin Roughage
Research in Veterinary Science, 1970Preliminary investigations into the chemical nature of a hepatotoxic factor which sometimes occurs in dried lupin roughage, particularly in Western Australia, have been carried out. Results indicated it was not an alkaloid. Its properties suggested the presence of phenolic and/or acidic groups.
D S, Petterson, W H, Parr
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Are Mould Hepatotoxins Responsible for Kava Hepatotoxicity?
Phytotherapy Research, 2012Previous studies with kava components such as kavalactones, pipermethystine and flavokavain B have demonstrated hepatotoxicity from these constituents. Regardless, there has recently been speculation that adulterants or impurities such as the mould hepatotoxin aflatoxin are a more likely cause of kava hepatotoxicity, despite a paucity of supporting ...
Anthony, Rowe, Iqbal, Ramzan
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Bioaccumulation of hepatotoxins – A considerable risk in the Latvian environment
Environmental Pollution, 2015The Gulf of Riga, river Daugava and several interconnected lakes around the City of Riga, Latvia, form adynamic brackish-freshwater system favouring occurrence of toxic cyanobacteria. We examined bioaccumulation of microcystins and nodularin-R in aquatic organisms in Latvian lakes, the Gulf of Riga and west coast of open Baltic Sea in 2002-2007.
Barda, Ieva +6 more
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Identification of hepatotoxin‐producing cyanobacteria by DNA‐chip
Environmental Microbiology, 2008Summary We developed a new tool to detect and identify hepatotoxin‐producing cyanobacteria of the genera Anabaena , Microcystis , Planktothrix , Nostoc and
Anne Rantala +4 more
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Effect of hyperoxia on liver necrosis induced by hepatotoxins
Virchows Archiv B Cell Pathology Including Molecular Pathology, 1986We have tested the effects of hyperbaric oxygen on necrosis of rat liver induced by the administration of several toxins. The extent of liver necrosis was determined 24 h after the administration of the toxins by measurement of serum levels of alanine and aspartate amino-transferases and by histologic and ultrastructural analyses.
L, Marzella, K, Muhvich, R A, Myers
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OXIDATIVE BIOACTIVATION OF HALOFORMS INTO HEPATOTOXINS
1980This chapter discusses the oxidative bioactivation of haloforms into hepatotoxins. The hepatotoxin chloroform (CHCl 3 ) is converted to phosgene (COCl 2 ) by rat liver microsomes and in living rats. The reaction is oxygen dependent and appears to be catalyzed by cytochrome P-450.
L.R. Pohl +3 more
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Resistance of the regenerating liver to hepatotoxins
Bulletin of Experimental Biology and Medicine, 1976Administration of CCl4 and paracetamol to mice causes massive necrosis of the central regions of the hepatic lobule. Preliminary stimulation of hepatocyte proliferation by partial hepatectomy greatly reduces the intensity of the toxic effect or abolishes it completely, depending on the time elapsing after the operation.
I. V. Uryvaeva, V. M. Faktor
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Disposition of the hepatotoxin α-naphthylisothiocyanate (ANIT) in the rat
Toxicology and Applied Pharmacology, 1970Abstract The disposition of ANIT was investigated in the rat by examining quantitatively the tissue, organ, and subcellular distribution as well as the excretion pattern, of 14C at selected times after ANIT-14C administration. Approximately 70% of the radioactive material was absorbed from the gastrointestinal tract within 24 hr and was found widely ...
F, Capizzo, R J, Roberts
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