Results 81 to 90 of about 4,105 (286)

BLOOM OF PHYTOPLANKTONS IN ANZALI LAGOON AND IDENTIFICATION OF POISONOUS ALGAE

open access: yes‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 2003
During the period of 1979-1980 in Abkenar and Hendkhaleh in Anzali lagoon, 67 I genus of phytoplanktons belong to 5 phylum were identified. The results showed that there is two peaks of phytoplankton blooms during a year (summer and, autumn) in which ...
P. Nijatkhah manavi1; Sh. Oryan2; A. Rostaeian2; R. Naghshine2; S.M. Fatemi
doaj  

Development of a convenient in vivo hepatotoxin assay using a transgenic zebrafish line with liver-specific DsRed expression.

open access: yesPLoS ONE, 2014
Previously we have developed a transgenic zebrafish line (LiPan) with liver-specific red fluorescent protein (DsRed) expression under the fabp10a promoter. Since red fluorescence in the liver greatly facilitates the observation of liver in live LiPan fry,
Xiaoyan Zhang, Caixia Li, Zhiyuan Gong
doaj   +1 more source

A Spatially Directed Microneedle Patch Enables Intratumoral Co‐Delivery of FOLFIRINOX, Surufatinib, and Anti‐PD‐1 for Chemo‐Immunotherapy of Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
A double‐layered shell‐core microneedle patch is developed to co‐deliver FOLFIRINOX, surufatinib, and anti‐PD‐1 for localized chemo‐immunotherapy of PDAC. This strategy achieves sustained tumor suppression, reduces metastasis, and reprograms the TME by enhancing CD8+ T‐cell infiltration and inhibiting Tregs and M2 macrophages infiltration, while ...
Tingting Kong   +13 more
wiley   +1 more source

Hepatoprotective effect of silver nanoparticles synthesized using aqueous leaf extract of Rhizophora apiculata

open access: yesInternational Journal of Nanomedicine, 2019
Hongru Zhang,1 Joe Antony Jacob,2 Ziyu Jiang,3 Senlei Xu,1 Ke Sun,1 Zehao Zhong,1 Nithya Varadharaju,4 Achiraman Shanmugam21The Second Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210023, People’s Republic of ...
Zhang H   +7 more
doaj  

Combined hepatotoxin effect.

open access: yes, 2014
LiPan fry were treated with a mixture of four hepatotoxins with increasing dilution factors. “1″ indicates undiluted mixture with the following final concentrations in the treatment: 2.5 mg/L acetaminophen, 1 mg/L aspirin, 1 mg/L isoniazid and 0.1 mg/L ...
Xiaoyan Zhang (50085)   +2 more
core   +1 more source

Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery

open access: yesAdvanced Science, EarlyView.
Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae   +27 more
wiley   +1 more source

Hepatoprotective properties of new complex compound of germanium with a copper (medgerm) at experimental toxic hepatitis [PDF]

open access: yes, 2011
На моделі експериментального токсичного гепатиту встановлено, що профілактично-курсове застосування медгерму підвищує толерантність щурів до гепатотоксину та забезпечує більш сприятливий перебіг патологічного процесу, ніж референс-препарат.It is ...
Даниленко, А.І.   +3 more
core   +3 more sources

Hepatic hyperplasia and damages induces by zearalenone Fusarium mycotoxins in BALB/c mice

open access: yesArquivos de Gastroenterologia, 2012
CONTEXT: Zearalenone is a mycoestrogen and considered a mycotoxin. OBJECTIVE: To establish whether zearalenone produced hepatotoxicity via oral administration.
Pronobesh Chatopadhyay   +5 more
doaj   +1 more source

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

open access: yesAdvanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal   +5 more
wiley   +1 more source

Functional Relationships between Lipid Metabolism and Liver Regeneration

open access: yesInternational Journal of Hepatology, 2012
The regenerative capacity of the liver is well known, and the mechanisms that regulate this process have been extensively studied using experimental model systems including surgical resection and hepatotoxin exposure. The response to primary mitogens has
David A. Rudnick, Nicholas O. Davidson
doaj   +1 more source

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