Results 81 to 90 of about 3,849 (286)

Development of a convenient in vivo hepatotoxin assay using a transgenic zebrafish line with liver-specific DsRed expression.

PLoS ONE, 2014
Previously we have developed a transgenic zebrafish line (LiPan) with liver-specific red fluorescent protein (DsRed) expression under the fabp10a promoter. Since red fluorescence in the liver greatly facilitates the observation of liver in live LiPan fry,
Xiaoyan Zhang, Caixia Li, Zhiyuan Gong
doaj   +1 more source

Vascularized Liver‐on‐a‐Microsphere Reveals Alanine‐Glucose Metabolism‐Driven Regulation of Liver Function and Injury

Advanced Science, EarlyView.
A vascularized liver‐on‐a‐microsphere system is developed to recreate lobule‐like cellular organization and endothelial barrier function within compartmentalized hydrogel particles. The platform enhances hepatic performance and reveals alanine‐glucose cycle activation linked to improved detoxification capacity, offering a high‐throughput microscale ...
Jingyang Li, Zengnan Wu, Yingrui Zhang, Shulang Chen, Yongning Lin, Shiyu Chen, Tong Xu, Xianli Meng, Yi Zhang, Jin‐Ming Lin   +9 more
wiley   +1 more source

Uptake of the cyanobacterial hepatotoxin microcystin-RR by submergent macrophyte Vallisneria natans (Lour.) Hara. [PDF]

, 2004
Recently, heavy blooms frequently occured in Dianchi Lake and Microcystis is the main algae involved in blooms. Microcystis produces a family of related cyclic hepatopeptides( microcystins, MC). These toxins are severely hepatotoxic.
Huang Jia-Quan, Shen Qiang, Liu Yong-ding (liuyd@ihb.ac.cn), Yin Li-Yan, Li Dun-Hai, Inst Hydrobiol, Chinese Acad Sci, Wuhan, 430072, China   +5 more
core  

Hepatoprotective effect of silver nanoparticles synthesized using aqueous leaf extract of Rhizophora apiculata

International Journal of Nanomedicine, 2019
Hongru Zhang,1 Joe Antony Jacob,2 Ziyu Jiang,3 Senlei Xu,1 Ke Sun,1 Zehao Zhong,1 Nithya Varadharaju,4 Achiraman Shanmugam21The Second Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210023, People’s Republic of ...
Zhang H, Jacob JA, Jiang Z, Xu S, Sun K, Zhong Z, Varadharaju N, Shanmugam A   +7 more
doaj  

A Machine Vision‐Guided Microphysiological Platform With Automated Microfluidics Enables Longitudinal Biomarker Monitoring and Emulation of Translationally Relevant Exposure Scenarios

Advanced Science, EarlyView.
A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen, Yi Zhong, Laura Dangel, Sonia Youhanna, Reza Zandi Shafagh, Jinhye Ryu, Domnica‐Gabriela Gurau, Mathias Haag, Thomas E. Mürdter, Yingxin Liang, Iro Beligiani, Nicole Ziegler, Sabine Willems, Nayere Taebnia, Wouter van der Wijngaart, Volker M. Lauschke   +15 more
wiley   +1 more source

Hepatic hyperplasia and damages induces by zearalenone Fusarium mycotoxins in BALB/c mice

Arquivos de Gastroenterologia, 2012
CONTEXT: Zearalenone is a mycoestrogen and considered a mycotoxin. OBJECTIVE: To establish whether zearalenone produced hepatotoxicity via oral administration.
Pronobesh Chatopadhyay, Anurag Pandey, Asshwani K. Chaurasia, Addesh Upadhyay, Sanjev Karmakar, Lokendra Singh   +5 more
doaj   +1 more source

Gene Correction Enhances Dopaminergic Cell Therapy in a Nonhuman Primate Model of Parkinson's Disease

Advanced Science, EarlyView.
LRRK2‐mutant induced pluripotent stem cells (iPSCs) were derived from a patient with Parkinson's disease (PD). Using CRISPR/Cas9–mediated gene editing, the pathogenic LRRK2 mutations were precisely corrected, and isogenic dopaminergic neural progenitor cells (DA‐NPCs) were subsequently generated.
Qing Yan, Chongchong Xu, Jiangmei Gao, Pu Wang, Qingling Wu, Ying Jin, Binyan Lu, Mu Li, Mingting Shao, Bihai Li, Zhenghui Su, Yijng Zhang, Jianhuan Chen, Haojie An, Mengyao Huang, Xiaoji Zhuang, Yuhui Shen, Fenglin Wang, Nana Xu, Yiyan Liu, Lei Tang, Xiuling Zhong, Minyan Zhong, Jiecong Chen, Zhenhuang Wang, Xingrong Luo, Sheng Liu, RuiFeng Liu, Ling Zhang, Junhua Rao   +29 more
wiley   +1 more source

Removal of cyanotoxins by cyclodextrin complex, titanium dioxide photocatalysis and C₆₀ photocataly [PDF]

, 2010
The presence of cyanotoxins in surface and drinking water is a serious threat to the environment and human health. The most dangerous and widespread cyanotoxins include the microcystin and nodularin families (hepatotoxin), domoic acid (neurotoxin), and ...
Chen, Lin
core   +1 more source

Functional Relationships between Lipid Metabolism and Liver Regeneration

International Journal of Hepatology, 2012
The regenerative capacity of the liver is well known, and the mechanisms that regulate this process have been extensively studied using experimental model systems including surgical resection and hepatotoxin exposure. The response to primary mitogens has
David A. Rudnick, Nicholas O. Davidson
doaj   +1 more source

Eco‐Friendly Solvent System for Inkjet Deposition of Wide Bandgap Perovskite Solar Cells Enabling Tandem Integration

Advanced Science, EarlyView.
The fabrication of wide‐bandgap perovskite thin films via green solvents integrated with inkjet printing is developed. Controlled crystallization of the perovskite layer is achieved by optimizing ink formulation and additive engineering, enabling power conversion efficiencies above 17% for single junctions and 28% for perovskite/silicon tandem solar ...
Uma Kousalya Dangudubiyyam, Raphael Pesch, Ozan Karakaya, Theresa Kuechle, Faranak Sadegh, Nils W. Rosemann, Henry Weber, Ralf Niemann, Fabian Fertig, Johannes Sutter, Jinzhao Li, Gerardo Hernandez Sosa, Ulrich W. Paetzold   +12 more
wiley   +1 more source