Results 101 to 110 of about 3,849 (286)
Nodularia spumigena blooms and the occurrence of hepatotoxin in the Gulf of Gdańsk
Oceanologia, 2003 Nodularia spumigena forms extensive summer blooms in the Baltic Sea. The occurrence of the blooms is determined by water temperature, light intensity and nutrient concentration; levels of nitrogen and phosphorus in particular are critical.
Hanna Mazur, Marcin Pliński
doaj
Programmable Nanobody‐Targeting Chimeras Enable Intracellular Viral Protein Degradation
Advanced Science, EarlyView.Nab‐TAC enables targeted degradation of HBV surface antigen (HBsAg) in vivo. By fusing nanobody‐based recognition domains with programmable proteasome‐recruiting degradation signals, Nab‐TAC reduces HBsAg levels in a hydrodynamic HBV mouse model. ABSTRACT Chronic hepatitis B virus (HBV) infection remains a major global health challenge, largely because
Max Yu‐Chen Pan +11 more
wiley +1 more source
Advanced Science, EarlyView.Through AI‐assisted screening from FDA‐approved API to overcome the limitations of bacterial osteomyelitis treatment, glycyrrhizic acid and simvastatin are identified as a multifunctional combination capable of self‐assembling into mechanism‐targeting nanocrystals that effectively neutralize reactive oxygen species, suppress M1 macrophage polarization,
Yu Han +11 more
wiley +1 more source
Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression
Hepatology, EarlyView., 2022 Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández +18 more
wiley +1 more source
Clinical and Pathologic Findings of Blue-Green Algae (Microcystis aeruginosa) Intoxication in a Dog [PDF]
, 1993 A healthy dog developed signs of lethargy and vomiting after ingesting water from a tide pool containing blue-green algae. Fulminant hepatic failure occurred, and the dog was euthanized 52 hours later.
F. D. Galey +3 more
core +1 more source
Journal of Applied Botany and Food Quality, 2012 Spirodela intermedia was exposed to low (10 µg L-1) and high concentration (100 µg L-1) of microcystin-RR (Arginin-Arginin) over aperiod of two weeks. Depuration in the water phase, as weIl as uptake in the plant was determined using HPLC with photodiode
T. C. R. Ferreira +4 more
doaj
Advanced Science, EarlyView.A programmable encapsulation technology is developed to reduce bacterial immunogenicity and proliferation after systemic administration. The cross‐linked polymer networks around individual bacteria enable immunogenic shielding and permit selective proliferation in tumors, allowing the bacteria to convert tumor‐accumulated ammonia into L‐arginine and ...
Jianhui Yang +12 more
wiley +1 more source
Hepatology, EarlyView., 2022 NRPT 1X reduces ALT and ceramide 14:0 in 65% of subjects as compared to only 28% in the placebo group. Abstract Background and Aims The prevalence of NAFLD is increasing globally and on a path to becoming the most frequent cause of chronic liver disease. Strategies for the prevention and treatment of NAFLD are urgently needed.
Ryan W. Dellinger +7 more
wiley +1 more source
The photocatalytic destruction of the cyanotoxin, nodularin using TiO 2 [PDF]
, 2005 Titanium dioxide (TiO2) photocatalysis has been used to initiate the destruction of nodularin, a natural hepatotoxin produced by cyanobacteria. The destruction process was monitored using liquid chromatography-mass spectrometry analysis which has also ...
Lawton, Linda A. +4 more
core +2 more sources