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The role of the iron homeostasis mechanism is summarized in this article. Iron plays an important role in managing bodily functions such as growth and development, and makes haemoglobin, and some hormones. Hepcidin acts differently in different conditions; if the body needs more oxygen, the hepcidin levels decrease allowing iron to enter the plasma and
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Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
Nature Genetics, 2006Jodie L Babitt +2 more
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Regulation of the Iron Homeostatic Hormone Hepcidin
Advances in Nutrition, 2017Veena Sangkhae, Elizabeta Nemeth
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Hepcidin-Induced Endocytosis of Ferroportin Is Dependent on Ferroportin Ubiquitination
Cell Metabolism, 2012Priscilla Sugianto +2 more
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A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression
Cell Metabolism, 2005Tracey Ann Rouault
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Iron Regulator Hepcidin Impairs Macrophage-Dependent Cardiac Repair After Injury
Circulation, 2019Philippe Bonnin +2 more
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