Results 51 to 60 of about 48,931 (300)

Laparoscopic Delivery of a MnO2‐P‐ICG Patch for Photodynamic Therapy and NK Cell‐Driven Immunotherapy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
This study proposes a flexible MnO2‐P‐ICG nanofiber patch for laparoscopic treatment of liver tumors. The patch alleviates tumor hypoxia and induces photodynamic therapy (PDT) triggered immunogenic cell death, thereby activating the cGAS‐STING pathway and, in synergy with pachymaran, promoting NK cell–mediated innate immunity. This synergistic strategy
Jie Lin, Haoqi Pan, Ke Wu, Junjie Nan, Jinyao Dai, Yushun Chang, Hao Shen, Qingxuan Ye, Haowen Lu, Yuxuan Shen, Boqiang Liu, Ming Wu, Jicheng Yu, Xiujun Cai, Dong Cen   +14 more
wiley   +1 more source

The involvement of human organic anion transporting polypeptides (OATPs) in drug-herb/food interactions

Chinese Medicine, 2020
Organic anion transporting polypeptides (OATPs) are important transporter proteins that are expressed at the plasma membrane of cells, where they mediate the influx of endogenous and exogenous substances including hormones, natural compounds and many ...
Youmna Ali, Tahiatul Shams, Ke Wang, Zhengqi Cheng, Yue Li, Wenying Shu, Xiaofeng Bao, Ling Zhu, Michael Murray, Fanfan Zhou   +9 more
doaj   +1 more source

Excipient Emulsion–Based Delivery Systems for Enhancing Carotenoid Bioavailability: Advances in Formulation and Gastrointestinal Fate

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Excipient emulsion systems improve carotenoid solubilization, protect against degradation, and enhance gastrointestinal absorption through optimized formulation and digestion behavior. ABSTRACT Carotenoids are bioactive compounds that contribute to human health through antioxidant, provitamin A, and disease‐preventive effects.
Tugce Ceyhan, Elifsu Nemli, Esra Capanoglu, Merve Tomas   +3 more
wiley   +1 more source

In vitro inhibitory effects of kaempferitrin on human liver cytochrome P450 enzymes

Pharmaceutical Biology, 2019
Context: Kaempferitrinis (KF) is a bioactive flavonoid and possesses numerous pharmacological activities. However, whether KF affects the activity of human liver cytochrome P450 (CYP) enzymes remains unclear.
Ning Zhang, Jing Liu, Zhixia Chen, Wenwen Dou   +3 more
doaj   +1 more source

Herbal Databases for PDAs: Advice from Two Librarians [PDF]

, 2004
With more Americans using herbal remedies and dietary supplements, health practitioners are striving to increase their knowledge in this area. Health care providers are also increasingly turning to handheld computers for access to medical information at ...
Hartel, Lynda Jones, Kupferberg, Natalie
core   +1 more source

Real-world evidence of the herb-drug interactions

Journal of Food and Drug Analysis, 2022
Herbal medicine (HM) is a type of medicine that uses active ingredients made from plants to treat diseases and maintain health and wellbeing. Due to its increasing worldwide usage, the possibility of HMs and conventional drugs being concurrently used is high, potentially leading to adverse events resulting from herb-drug interactions.
Pan, Hsueh-Yi, Wu, Li-Wei, Wang, Pin-Chun, Chiu, Ping-Hung, Wang, Meng-Ting   +4 more
openaire   +2 more sources

Toward Predictable Nanomedicine: Current Forecasting Frameworks for Nanoparticle–Biology Interactions

Advanced Intelligent Discovery, EarlyView.
Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova, Michael Nicholls, Nicola Russo, Gueorgui Mihaylov, Konstantin Nikolic   +4 more
wiley   +1 more source

Potential pharmacokinetic interactions with concurrent use of herbal medicines and a ritonavir-boosted COVID-19 protease inhibitor in low and middle-income countries

Frontiers in Pharmacology, 2023
The COVID-19 pandemic sparked the development of novel anti-viral drugs that have shown to be effective in reducing both fatality and hospitalization rates in patients with elevated risk for COVID-19 related morbidity or mortality.
Dallas J. Smith, Dallas J. Smith, Huichang Bi, Josias Hamman, Xiaochao Ma, Constance Mitchell, Kumbukani Nyirenda, Tsitsi Monera-Penduka, Hellen Oketch-Rabah, Mary F. Paine, Syril Pettit, Wihan Pheiffer, Richard B. Van Breemen, Michelle Embry   +13 more
doaj   +1 more source

How safe are herbal products? [PDF]

, 2000
In the search for cures for his ailments, man discovered many healing and toxic properties of plants. Some were found to cure certain diseases while others were found to exert dramatic effects on the body.
Forte, John Stephen
core  

An assessment of the impact of herb-drug combinations used by cancer patients [PDF]

, 2016
Background Herb/Dietary Supplements (HDS) are the most popular Complementary and Alternative Medicine (CAM) modality used by cancer patients and the only type which involves the ingestion of substances which may interfere with the efficacy and safety of
A Fugh-Berman, A Goey, A Molassiotis, AA Izzo, AA Izzo, AH Lee, C Gratus, E Ernst, E Russo, Elizabeth M. Williamson, EM Williamson, EM Williamson, FU Afifi, I Meijerman, J Hübner, J Mclay, JR Suchard, JS McCune, K Chrystal, KA Vickers, M Heinrich, M Rotblatt, M Thomsen, O Kelber, P Champy, R Hermann, R Tian, R Zachariae, Rachel L. Howard, RH Mathijssen, RS Wold, S Engdal, S Tuna, Saud M. Alsanad, SM Alsanad, T Zeller, U Werneke, W Abebe, Y Cui   +38 more
core   +1 more source