Results 51 to 60 of about 94,301 (231)
A Brief History of IL-1 and IL-1 Ra in Rheumatology
Frontiers in Pharmacology, 2017 The history of what, in 1979, was called interleukin-1 (IL-1), orchestrator of leukocyte inter-communication, began many years before then, initially by the observation of fever induction via the endogenous pyrogen (EP) (1974) and then in rheumatology on
Jean-Michel Dayer +2 more
doaj +1 more source
Síndromes auto-inflamatórias: relato de três casos [PDF]
, 2009 CONTEXT: Autoinflammatory syndromes are diseases manifested by recurrent episodes of fever and inflammation in multiple organs. There is no production of autoantibodies, but interleukins play an important role and acute-phase reactants show abnormalities.
Barbosa, Cassia Maria Passarelli Lupoli +5 more
core +1 more source
Untangling the Web of Systemic Autoinflammatory Diseases
Mediators of Inflammation, 2014 The innate immune system is involved in the pathophysiology of systemic autoinflammatory diseases (SAIDs), an enlarging group of disorders caused by dysregulated production of proinflammatory cytokines, such as interleukin-1β and tumor necrosis factor-α,
Donato Rigante +14 more
doaj +1 more source
Pustular Eruptions in Children as Manifestations of Autoinflammatory Diseases
Revista da Sociedade Portuguesa de Dermatologia e Venereologia, 2019 Nowadays, in clinical practice, when attending a child with a pustular eruption and systemic inflammation, it is mandatory to think of an autoinflammatory disease, once infectious causes have been ruled out.
Felicidade Santiago, Antonio Torrelo
doaj +1 more source
Frontiers in Immunology, 2021 BackgroundInterleukin (IL)-1 inhibitors represent the main treatment in patients with colchicine-resistant/intolerant familial Mediterranean fever (crFMF), mevalonate kinase deficiency (MKD), and tumor necrosis factor receptor-associated periodic ...
Caroline Vinit +19 more
doaj +1 more source
Increased levels of circulating Annexin A5 in Familial Mediterranean fever [PDF]
, 2010 Background Familial Mediterranean fever is a genetic autoinflammatory disease most commonly affecting the ethnic groups originating from around the Mediterranean Sea.
Anna S Boyajyan +3 more
core +1 more source
Arthritis Care &Research, EarlyView.Objective Relapsing polychondritis (RP) is a rare disease defined by recurrent cartilaginous inflammation. Anti–collagen II (Col2) antibodies have been proposed as a diagnostic biomarker for RP, but their performance characteristics are not well defined.
Karyssa Stonick +6 more
wiley +1 more source
Familial Mediterranean fever: What associations to screen for?
Rheumatology, 2020 Familial Mediterranean fever (FMF) is the most common and best known of hereditary recurrent fever or periodic fever syndromes. It was described in 1945 and genetically characterized in 1992.
Salem Bouomrani +2 more
doaj +1 more source
Analysis of the genetic basis of periodic fever with aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome. [PDF]
, 2015 PFAPA syndrome is the most common autoinflammatory syndrome in children from Western countries. In spite of its strong familial clustering, its genetic basis and inheritance pattern are still unknown.
Bedoni, N. +6 more
core +3 more sources
Annals of the Rheumatic Diseases, 2018 Autoinflammatory diseases (AIDs) are a relatively new family of disorders, defined about 19 years ago. Some of them are hereditary and some are not.
E. Ben-Chetrit +6 more
semanticscholar +1 more source