Results 61 to 70 of about 2,214,075 (211)

Autoinflammatiós kórképek = Autoinflammatory diseases [PDF]

, 2018
Absztrakt: Az autoinflammatiós szindrómák a veleszületett immunrendszert érintő, visszatérő szisztémás gyulladásos tünetekkel, súlyos szövődményekkel jellemezhető kórképek.
Mosdósi, Bernadett, Bernadett Mosdósi, Beáta Tóth, Tóth, Beáta   +3 more
core   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Human Monocytic Models Reveal Genotype‐Dependent Inflammatory Programs in VEXAS Syndrome

Arthritis &Rheumatology, EarlyView.
Objective VEXAS syndrome is a severe X‐linked autoinflammatory disorder caused by somatic mutations in ubiquitin‐like modifier activating enzyme 1 (UBA1), with clinical outcomes that vary by UBA1 genotype. We aimed to elucidate genotype‐specific inflammatory programs and identify potential therapeutic targets.
Kana Higashitani, Tatsuma Ban, Yohei Kirino, Go R. Sato, Soichiro Adachi, Yuki Iizuka, Kayo Harita, Ayaka Maeda, Osamu Ohara, Hideaki Nakajima, Tomohiko Tamura   +10 more
wiley   +1 more source

Shared and Distinguishing Features of Late‐Onset Rheumatic Diseases Fulfilling Polymyalgia Rheumatica Classification Criteria

Arthritis &Rheumatology, Accepted Article.
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Kerem Abacar, Ala Altaie, Andrew Barr, Sarah L. Mackie, Kulveer Mankia, Dennis McGonagle   +5 more
wiley   +1 more source

The expanding spectrum of rare monogenic autoinflammatory diseases. [PDF]

, 2013
International audience: Monogenic autoinflammatory diseases are a group of hereditary disorders characterized by a clinical and biological inflammatory syndrome in which there is little or no evidence of autoimmunity. The discovery of the first causative
Galeotti, Caroline, Véronique Hentgen, Piram, Maryam, Isabelle Koné-Paut, Rossi-Semerano, Linda, Hentgen, Véronique, Koné-Paut, Isabelle, Isabelle Touitou, null null, Caroline Galeotti, Touitou, Isabelle, Maryam Piram, Linda Rossi-Semerano   +12 more
core   +1 more source

Recommendations for the management of autoinflammatory diseases [PDF]

, 2015
Autoinflammatory diseases are characterised by fever and systemic inflammation, with potentially serious complications. Owing to the rarity of these diseases, evidence-based guidelines are lacking.
Uziel, Y., Wouters, C., Simon, A, Grateau, Gilles, Ozdogan, H, Russo, R, Cantarini, Luca, Ozen, S., Brogan, P., Jeyaratnam, Jerold, Feldman, Brian M., ter Haar, N, Vastert, B, Wulffraat, N., Jeyaratnam, J, Oswald, M, Brogan, Paul A., Lachmann, Helen J., Frenkel, Joost, Kone-Paut, I, Feldman, B.M., Brogan, Paul A, Frenkel, J., Grateau, G., Haar, N.M.R. van der, Wouters, C, Frenkel, J, Hentgen, V, Hofer, M, Barron, Karyl S, Grateau, G, Wulffraat, N, Uziel, Yosef, Kuemmerle-Deschner, J.B., Kallinich, Tilmann, Simon, A., Benseler, S.M., Kallinich, T, Kuemmerle-Deschner, J., Jeyaratnam, J., Hofer, M., ter Haar, N., Feldman, Brian M, Gattorno, M, Kone-Paut, I., Benseler, S., Ozdogan, Huri, Simon, Anna, Hofer, Michael, Galeotti, C., Benseler, Susanne M, Kone-Paut, Isabelle, Lachmann, H.J., Lachmann, Helen J, Anton, J., Cantarini, L., Hentgen, V., Benseler, S, Galeotti, Caroline, Barron, K., Vastert, SJ, Feldman, B., Feldman, B, Oswald, M., Ozen, Seza, Ter Haar, Nienke M, Hentgen, Veronique, Gattorno, M., Barron, K.S., Vastert, S.J., Ozdogan, H., Wouters, Carine, Wulffraat, Nico M., Kuemmerle-Deschner, J, Kuemmerle-Deschner, Jasmin B., Vastert, Sebastiaan J., Kallinich, T., Brogan, P, Barron, K, Anton, Jordi, Cantarini, L, Brogan, P.A., Wulffraat, Nico M, Vastert, B., Gattorno, Marco, Lachmann, H., Kuemmerle Deschner, Jasmin B., Kone Paut, Isabelle, Anton, J, Russo, Ricardo, Benseler, Susanne M., Galeotti, C, Wulffraat, Nico W., Uziel, Y, Russo, R., ter Haar, Nienke M., Barron, Karyl S., Vastert, Sebastiaan J, Wulffraat, N.M., Oswald, Marlen, Lachmann, H   +100 more
core   +5 more sources

Pluripotent stem cell‐based screening identifies CUDC‐907 as an effective compound for restoring the in vitro phenotype of Nakajo‐Nishimura syndrome

Stem Cells Translational Medicine, 2021
Nakajo‐Nishimura syndrome (NNS) is an autoinflammatory disorder caused by a homozygous mutations in the PSMB8 gene. The administration of systemic corticosteroids is partially effective, but continuous treatment causes severe side effects.
Naoya Kase, Madoka Terashima, Akira Ohta, Akira Niwa, Fumiko Honda‐Ozaki, Yuri Kawasaki, Tatsutoshi Nakahata, Nobuo Kanazawa, Megumu K. Saito   +8 more
doaj   +1 more source

Molecular Biomarkers in Meniere's Disease: A Scoping Review of Current Evidence

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Meniere's disease is a complex chronic inner ear condition that is characterized by vertigo, tinnitus, aural fullness, and progressive hearing loss. Currently, diagnostic strategies remain symptom‐driven, and treatments focus on management of discrete episodes rather than targeting underlying pathophysiology.
Hamza Kamran, Zaharadeen Jimoh, Tariq Issa, Nahla A. Gomaa   +3 more
wiley   +1 more source

TRAPS: An Autosomal Dominant Autoinflammatory Syndrome

Eurasian Journal of Medicine, 2019
Hereditary periodic fever syndromes are genetic autoinflammatory disorders characterized by recurrent attacks of fever and inflammation. These diseases include familial Mediterranean fever (FMF), Tumor necrosis factor receptor-associated periodic ...
Saliha Karatay, Meltem Alkan Melikoğlu
doaj  

Computational Modeling of NLRP3 Identifies Enhanced ATP Binding and Multimerization in Cryopyrin-Associated Periodic Syndromes

Frontiers in Immunology, 2020
Cyropyrin-associated periodic syndromes (CAPS) are clinically distinct syndromes that encompass a phenotypic spectrum yet are caused by alterations in the same gene, NLRP3.
Jenny Mae Samson, Dinoop Ravindran Menon, Prasanna K. Vaddi, Nazanin Kalani Williams, Joanne Domenico, Zili Zhai, Donald S. Backos, Mayumi Fujita, Mayumi Fujita, Mayumi Fujita   +9 more
doaj   +1 more source