Results 81 to 90 of about 16,165 (220)
Molecular Genetics &Genomic Medicine, Volume 13, Issue 3, March 2025.Patients recruited from the oncogenetic department with multiple cancers (348) were more likely to carry pathogenic mutations than those with a single cancer (1422) (27.3% vs. 13.39% p < 0.001). However, if the multiple primary cancers cannot be linked to the same hereditary predisposition syndrome, the prevalence of pathogenic variants is not ...
Mathis Lepage +7 more
wiley +1 more source
Hereditary Colorectal Cancer (CRC) Program in Latvia [PDF]
, 2003 Introduction The aim of the study is to evaluate the incidence and phenotype - genotype characteristics of hereditary colorectal cancer syndromes in Latvia in order to develop the basis of clinical management for patients and their relatives affected by ...
Arvids Irmejs +8 more
core +2 more sources
Gynecologic Oncology Reports, 2018 Sebaceous carcinomas are rare tumors, with the majority of described cases occurring within the eyelid. To date, there are nine documented reports of sebaceous carcinoma arising within a mature cystic teratoma of the ovary. Although the majority of cases
Alyssa Wield +5 more
doaj +1 more source
Familial colorectal cancer: eleven years of data from a registry program in Switzerland [PDF]
, 2018 Deleterious germ-line variants involving the DNA mismatch repair (MMR) genes have been identified as the cause of the hereditary nonpolyposis colorectal cancer syndrome known as the Lynch syndrome, but in numerous familial clusters of colon cancer, the ...
Haider, Ritva +6 more
core
Recognition and management of hereditary colorectal cancer syndromes [PDF]
, 2009 Over 1,900 colorectal tumors will arise in association with a hereditary colorectal cancer syndrome in Spain in 2009. The genetic defects responsible for the most common syndromes have been discovered in recent years. Genetic testing
Herraiz-Bayod, M.J. (Maite J.) +1 more
core
Primary Sclerosing Epithelioid Fibrosarcoma of the Lung in a Patient with Lynch Syndrome [PDF]
, 2018 Sclerosing epithelioid fibrosarcoma (SEF) is a rare neoplasm arising mostly in limbs and limb girdles, with a high rate of recurrence and a strong tendency to metastasize.
Jungraithmayr, Wolfgang +3 more
core
The story of hereditary nonpolyposis colorectal cancer: celebrating the spirit of investigation. [PDF]
IGIE, 2023 Lynch PM, Ge PS.
europepmc +1 more source
SPECIAL FEATURES OF CARCINOGENESIS OF COLON ADENOCARCINOMA
Сибирский онкологический журнал, 2016 Colorectal cancer is one of the most common malignancies and the leading cause of cancer-related death. There are 4 basic colon carcinogenic steps: malignant transformation of adenoma into carcinoma; HNPCC (hereditary nonpolyposis colon cancer); cancer ...
G. A. Raskin, S. V. Petrov, R. V. Orlova
doaj
Reduced expression of alanyl aminopeptidase is a robust biomarker of non-familial adenomatous polyposis and non-hereditary nonpolyposis colorectal cancer syndrome early-onset colorectal cancer. [PDF]
Cancer Med, 2023 Ha YJ +9 more
europepmc +1 more source
Numbers of mutations to different types of colorectal cancer
BMC Cancer, 2005 Background The numbers of oncogenic mutations required for transformation are uncertain but may be inferred from how cancer frequencies increase with aging. Cancers requiring more mutations will tend to appear later in life.
Tavaré Simon +5 more
doaj +1 more source