Results 101 to 110 of about 31,297 (199)

A superfamily of small potassium channel subunits: form and function of the MinK-related peptides (MiRPs). [PDF]

, 1998
MinK and MinK-related peptide I (MiRPI) are integral membrane peptides with a single transmembrane span. These peptides are active only when co-assembled with pore-forming K+ channel subunits and yet their role in normal ion channel behaviour is ...
Abbott, GW, Goldstein, SA
core  

Phosphorylation and protonation of neighboring MiRP2 sites: function and pathophysiology of MiRP2-Kv3.4 potassium channels in periodic paralysis. [PDF]

, 2006
MinK-related peptide 2 (MiRP2) and Kv3.4 subunits assemble in skeletal muscle to create subthreshold, voltage-gated potassium channels. MiRP2 acts on Kv3.4 to shift the voltage dependence of activation, speed recovery from inactivation, suppress ...
Abbott, Geoffrey W, Butler, Margaret H, Goldstein, Steve AN   +2 more
core   +1 more source

hERG agonists pose challenges to web-based machine learning methods for prediction of drug-hERG channel interaction

, 2023
Aziza El Harchi, Jules C. Hancox
openalex   +1 more source

LncRNA MALAT1/Calpain-1 Axis in ATO Induced hERG Channel Deficiency

Drug Design, Development and Therapy
Caichuan Yan,* Yuexin Li,* Xiaoxu Li, Yang Li, Yuhao Zhang, Jinyang Sun, Qirui Ding, Xin Zhao, Baoxin Li Department of Pharmacology, College of Pharmacy, Harbin Medical University, Harbin, People’s Republic of China*These authors contributed ...
Yan C, Li Y, Li X, Li Y, Zhang Y, Sun J, Ding Q, Zhao X, Li B   +8 more
doaj  

The four and a half LIM domain protein 2 interacts with and regulates the HERG channel [PDF]

, 2008
Jijin Lin, Shuguang Lin, Xiyong Yu, Patrick C. Choy, Xiuzhang Shen, Chunyu Deng, Su‐Juan Kuang, Jun Wu   +7 more
openalex   +1 more source

Modulation of HERG K⁺ Channels by Chronic Exposure to Activators and Inhibitors of PKA and PKC: Actions Independent of PKA and PKC Phosphorylation [PDF]

, 2013
Liliang Shu, Wanzhe Zhang, Gang Su, Jingchao Zhang, Chao Liu, Jing Xu   +5 more
openalex   +1 more source

Mechanism and pharmacological rescue of berberine-induced hERG channel deficiency

Drug Design, Development and Therapy, 2015
Meng Yan,1 Kaiping Zhang,1 Yanhui Shi,1 Lifang Feng,1 Lin Lv,1 Baoxin Li1,2 1Department of Pharmacology, Harbin Medical University, 2State-Province Key Laboratory of Biopharmaceutical Engineering, Harbin, Heilongjiang, People’s Republic of China ...
Yan M, Zhang KP, Shi YH, Feng LF, Lv L, Li BX   +5 more
doaj  

Sulfoximine-substituted trifluoromethylpyrimidine analogs as inhibitors of proline-rich tyrosine kinase 2 (PYK2) show reduced hERG activity

, 2009
Daniel P. Walker, Michael P. Zawistoski, Molly A. McGlynn, Jiancheng Li, Daniel W. Kung, Peter C. Bonnette, Amy Baumann, Leonard Buckbinder, Janet A. Houser, Jason Boer, Anil Mistry, Seungil Han, Li Xing and Angel Guzman-Perez   +12 more
openalex   +1 more source

Normal function of HERG K⁺ channels expressed in HEK293 cells requires basal protein kinase B activity [PDF]

, 2002
Yiqiang Zhang, Huizhen Wang, Jingxiong Wang, Ho Jae Han, Stanley Nattel, Zhiguo Wang   +5 more
openalex   +1 more source

A Receptor-Independent Effect of Estrone Sulfate on the hERG Channel

, 2009
Shoko Kakusaka, Mahoko Asayama, Asami Kaihara, Tetsuo Sasano, Takeshi Suzuki, Junko Kurokawa, Tetsushi Furukawa   +6 more
openalex   +2 more sources