Norpropoxyphene-induced cardiotoxicity is associated with changes in ion-selectivity and gating of HERG currents [PDF]
, 1999 Chris Ulens
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Specific block of cloned Herg channels by clofilium and its tertiary analog LY97241 [PDF]
, 1997 H. Suessbrich +4 more
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Gene Therapy in Cardiac Arrhythmias [PDF]
, 2006 Gene therapy has progressed from a dream to a bedside reality in quite a few human diseases. From its first application in adenosine deaminase deficiency, through the years, its application has evolved to vascular angiogenesis and cardiac arrhythmias.
Francis, Johnson +2 more
core
hERG toxicity assessment: Useful guidelines for drug design.
European journal of medicinal chemistry, 2020 Amanda Garrido +4 more
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Sequence and function of the two P domain potassium channels: implications of an emerging superfamily. [PDF]
, 1998 A new superfamily of K+ channels has emerged in the past 2 years. Notable for possessing two pore-forming P domains in each subunit, members of the superfamily have been recognized through phylogeny from micro-organisms to humans. Four subfamilies of two
Goldstein, SA +3 more
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Novel missense mutation (G601S) of HERG in a Japanese long QT syndrome family [PDF]
, 1998 Kaoru Akimoto +7 more
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From bench to bedside: Tracing the payback forwards from basic or early clinical research – A preliminary exercise and proposals for a future study [PDF]
, 2010 EXECUTIVE SUMMARY Chapter 1 : Introduction • The members of the research team from HERG and the Wellcome Trust have conducted previous studies showing that it is possible both to assess the payback from applied health research, and to use bibliometrics
Buxton, MJ +4 more
core
Trapping of a Methanesulfonanilide by Closure of the Herg Potassium Channel Activation Gate [PDF]
, 2000 John S. Mitcheson +2 more
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The Dominant Negative LQT2 Mutation A561V Reduces Wild-type HERG Expression [PDF]
, 2000 Anna Kagan +3 more
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Survey of the coding region of the HERG gene in long QT syndrome reveals six novel mutations and an amino acid polymorphism with possible phenotypic effects [PDF]
, 2000 Päivi Laitinen +7 more
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