Results 161 to 170 of about 31,297 (199)

2-(4-Carbonylphenyl)benzoxazole inhibitors of CETP: Attenuation of hERG binding and improved HDLc-raising efficacy

, 2011
Ramzi F. Sweis, Julianne A. Hunt, Peter M. Sinclair, Ying Chen, Suzanne S. Eveland, Qiu Guo, Sheryl A. Hyland, Denise P. Milot, Anne-Marie Cumiskey, Melanie Latham, Raymond Rosa, Larry Peterson, Carl P. Sparrow, Matt S. Anderson   +13 more
openalex   +1 more source

Age- and sex-dependent mRNA expression of KCNQ1 and HERG in patients with long QT syndrome type 1 and 2 [PDF]

, 2011
Ewa Moric‐Janiszewska, Joanna Głogowska‐Ligus, Monika Paul-Samojedny, Ludmiła Węglarz, Grażyna Markiewicz‐Łoskot, Lesław Szydłowski   +5 more
openalex   +1 more source

Molecular insights into the bioactivity of H-thiazine compounds against breast cancer cells: a computational study. [PDF]

In Silico Pharmacol
Mogoane LM, Obakachi VA, Govender PP, Govender KK.   +3 more
europepmc   +1 more source

Identification of a novel dual-targeting peptide inhibitor of SARS-CoV-2 RBD and NRP1 through structure-based virtual screening. [PDF]

Front Pharmacol
Yao N, Guan L, Feng L, Wang G, Wang Y, Niu MM, Yu M, Yin S.   +7 more
europepmc   +1 more source

HERGAI: an artificial intelligence tool for structure-based prediction of hERG inhibitors. [PDF]

J Cheminform
Tran-Nguyen VK, Randriharimanamizara UF, Taboureau O.   +2 more
europepmc   +1 more source

Virtual Screening-Guided Discovery of a Selective TRPV1 Pentapeptide Inhibitor with Topical Anti-Allergic Efficacy. [PDF]

Cells
Liu L, Hou W, He Q, Yuan F, Guo C, Liu R, Huang B, Wubulikasimu A, Rong M.   +8 more
europepmc   +1 more source

Overcoming HERG affinity in the discovery of the CCR5 antagonist maraviroc

, 2006
David A. Price, Duncan Armour, Marcel de Groot, Derek J. Leishman, Carolyn Napier, Manos Perros, Blanda Stammen, Anthony Wood   +7 more
openalex   +1 more source

Voltage sensor conformations induced by LQTS-associated mutations in hERG potassium channels. [PDF]

Nat Commun
Chan AN, Quach CD, Handlin LJ, Lessie EN, Tajkhorshid E, Dai G.   +5 more
europepmc   +1 more source

Unveiling optimal molecular features for hERG insights with automatic machine learning. [PDF]

J Pharm Anal
Xu C, Xu Y, Hu Z, Zhao X, Xie W, Chen W, Pei J.   +6 more
europepmc   +1 more source

Harnessing AlphaFold to reveal hERG channel conformational state secrets. [PDF]

Elife
Ngo K, Yang PC, Yarov-Yarovoy V, Clancy CE, Vorobyov I.   +4 more
europepmc   +1 more source