Results 141 to 150 of about 28,801 (226)

Reassessing the Conduct of Patch Clamp Cardiac Ion Channel Assays to Improve Nonclinical Data Translation to Clinical ECG Changes and Proarrythmia Risk. [PDF]

Clin Transl Sci
Alvarez Baron C, Zhao J, Guo D, Mistry S, De Palma R, Ismaiel OA, Wu WW.   +6 more
europepmc   +1 more source

KCNH2-L693P Causes Long QT Syndrome Type 2 Through hERG Channel Dysfunction: Functional Validation of a Variant of Uncertain Significance. [PDF]

Mol Genet Genomic Med
Zheng XF, Chen Q, Lu XT, Dai HL, Guang XF.   +4 more
europepmc   +1 more source

Biomimetic Partitioning and Pharmacokinetic Insights into Phytocannabinoids. [PDF]

ACS Omega
Martin JK, Muensterman DJ, Droz B, Valko K, Truong L, Tanguay RL, Field JA.   +6 more
europepmc   +1 more source

Development of cell-active BRD4-D1 selective inhibitors to decode the role of BET proteins in LPS-mediated liver inflammation. [PDF]

Eur J Med Chem
Scholtz CR, Doskey LC, Kandanur SGS, Vail NR, Roderick ER, Peterson EJ, Hoell ZJ, Shi K, Aihara H, Kostallari E, Shah VH, Malhi H, Pomerantz WCK.   +12 more
europepmc   +1 more source

Research on an innovative magnetic helix hybrid excitation rotary generator with remarkable power density and efficiency for wave energy conversion. [PDF]

Sci Rep
Liu Y, Yu H, Zhang Q.
europepmc   +1 more source

Models of hERG Block [PDF]

Biophysical Journal, 2018
Brandon Franks, Glenna C.L. Bett, Randall Rasmusson   +2 more
openaire   +1 more source

A novel near-infrared fluorescent hERG potassium channel probe for glioblastoma therapy and imaging. [PDF]

Chem Sci
Liu Z, Liu L, Ban T, Wang X, Li R, Zhang X, Wang Y, Li X, Zhang W, Li P, Tang B.   +10 more
europepmc   +1 more source

Evaluation of New Coumarins for Anti-Cancer Activity in HL-60 Cell Line Supported by Molecular Docking, MD Simulation, and Binding Free Energy Calculations. [PDF]

Onco Targets Ther
Humayun N, Rabbi F, Sohail M, Khan A, Zeb A, Nisar A, Rahim A, Shao C, Wang S, Younas A.   +9 more
europepmc   +1 more source

hERG Channel Blockade and Antagonistic Interactions of Three Steroidal Alkaloids from <i>Fritillaria</i> Species. [PDF]

Molecules
Lu H, Hao T, Zhang Z, Jiang C, Xu J, Stalin A, Zhao W.   +6 more
europepmc   +1 more source

Beyond the Genomic Storm: Evaluating Tabernanthalog as a Potential Scaffold for Silent Neuroplasticity and Broad-Spectrum Therapy. [PDF]

Int J Mol Sci
Anchesi I, Raffaele I, Astorino MF, Lui M, Calabrò M, Cipriano GL.   +5 more
europepmc   +1 more source