Delayed Repolarization Caused by hERG Block With Different Drug Modalities Can Be Detected in Stem Cell-Derived Cardiomyocytes: Incubation Time Matters. [PDF]
Clin Transl SciQu Y +6 more
europepmc +1 more source
Advanced cardiotoxicity profiling using field potential imaging with UHD-CMOS-MEA in human iPSC-derived cardiomyocytes. [PDF]
Toxicol SciMatsuda N +8 more
europepmc +1 more source
The molecular basis of KCNH1-related epileptic encephalopathy and the challenge of developing targeted therapeutics. [PDF]
BrainSundman AK, Jin S, Vadlamudi L, King GF.
europepmc +1 more source
Towards a unified gating scheme for the CNBD ion channel family. [PDF]
J Gen PhysiolLin JL, Chanda B.
europepmc +1 more source
Virtual Screening of Marine Natural Products Targeting the F Protein for Anti-RSV Drug Discovery. [PDF]
Int J Mol SciLiu W +5 more
europepmc +1 more source
Investigating the Risk of Arrhythmogenesis Associated With Fentanyl Abuse Using Human and Mouse Cardiomyocytes. [PDF]
CirculationMondéjar-Parreño G +10 more
europepmc +1 more source
QT interval prolongation: clinical assessment, risk factors and quantitative pharmacological considerations. [PDF]
J Pharmacokinet PharmacodynGotta V, Donner B.
europepmc +1 more source
Comparative pharmacoinformatic and quantum descriptor insights from BFM/GBTLI guidelines to phase I/II compounds for acute lymphoblastic leukemia (ALL). [PDF]
Sci RepBahia IAF +9 more
europepmc +1 more source
HERGAI: an artificial intelligence tool for structure-based prediction of hERG inhibitors. [PDF]
J CheminformTran-Nguyen VK +2 more
europepmc +1 more source
Identification of a novel dual-targeting peptide inhibitor of SARS-CoV-2 RBD and NRP1 through structure-based virtual screening. [PDF]
Front PharmacolYao N +7 more
europepmc +1 more source