Results 171 to 180 of about 5,479 (195)

HERG

2011
openaire   +1 more source

Class III Antiarrhythmic Drugs Block HERG, a Human Cardiac Delayed Rectifier K+ Channel : Open-Channel Block by Methanesulfonanilides

Circulation Research, 1996
Michael C Sanguinetti, M E Curran, Mark T Keating   +2 more
exaly  

HERG-channels

2006
openaire   +2 more sources

Development of Safe Drugs: The hERG Challenge

Medicinal Research Reviews, 2018
Khaled Barakat, Subha Kalyaanamoorthy
exaly  

An evaluation of hERG current assay performance: Translating preclinical safety studies to clinical QT prolongation

Pharmacology & Therapeutics, 2011
Gary Gintant
exaly  

Facilitation of hERG Current Occurs in Various hERG Channel Blockers

Journal of Molecular and Cellular Cardiology, 2008
Atsushi Inanobe, Kazuharu Furutani, Yoshihisa Kurachi⁎   +2 more
openaire   +1 more source

Coexistence of hERG current block and disruption of protein trafficking in ketoconazole-induced long QT syndrome

British Journal of Pharmacology, 2008
Brian P. Delisle, Y Otsuji, Craig T January   +2 more
exaly  

HERG-Lite®: A novel comprehensive high-throughput screen for drug-induced hERG risk

Journal of Pharmacological and Toxicological Methods, 2005
Eckhard Ficker, Arthur M Brown, Barbara A Wible   +2 more
exaly  

hERG-Att: Self-attention-based deep neural network for predicting hERG blockers

Computational Biology and Chemistry, 2020
Hojung Nam
exaly  

A quantitative assessment of hERG liability as a function of lipophilicity

Bioorganic and Medicinal Chemistry Letters, 2007
Michael J Waring
exaly