Results 181 to 190 of about 31,297 (199)

Nutritional Factors and Arrhythmic Risk in Long QT Syndrome: A Narrative Review of Mechanistic and Clinical Evidence. [PDF]

Adv Nutr
Mazzanti A, Floriano M, Kukavica D, Trancuccio A, Priori SG.   +4 more
europepmc   +1 more source

Modelling of clinical TQT studies outcomes from preclinical cardiovascular safety pharmacology studies using the one-step QTc model. [PDF]

Front Pharmacol
Champéroux P, Fares R, Leishman D.
europepmc   +1 more source

AI-Enabled Reduction of Animal Use in Cardiovascular Translational Medicine: Regulatory and Technological Perspectives. [PDF]

Life (Basel)
Dinc R, Ardic N.
europepmc   +1 more source

Large Language Models for Controllable Multi-property Multi-objective Molecule Optimization. [PDF]

Find ACL EMNLP
Dey V, Hu X, Ning X.
europepmc   +1 more source

Discovery of small molecule modulators of the thin filament that alter the contractile profile in a hypertrophic cardiomyopathy engineered tissue model. [PDF]

J Biol Chem
Sommese RF, Levi SM, Brown J, Polivkova J, Byrnes LJ, Kue R, Damilano F, Hua W, Boehm M, Dushin E, Filipski KJ, Kormos BL, Li Q, Miller R, Ogilvie K, Ridgway N, Smith AC, Stansfield JC, Wang Y, Withka J, Zhang H, Griffith DA, Ward J.   +22 more
europepmc   +1 more source

FDA's insights: implementing new strategies for evaluating drug-induced QTc prolongation. [PDF]

J Pharmacokinet Pharmacodyn
Ji Y, Johannesen L, Garnett C.
europepmc   +1 more source

The Cardiac Sodium Channel Safety Profile of Cenobamate at Therapeutic Concentrations: In Vitro Analyses. [PDF]

Clin Transl Sci
Crumb WJ, Melnick SM, Glenn KJ.
europepmc   +1 more source

A privileged ER compartment for posttranslational heteromeric assembly of an ion channel. [PDF]

Proc Natl Acad Sci U S A
Kannan S, Kasberg W, Ernandez LR, Audhya A, Robertson GA.   +4 more
europepmc   +1 more source

In-silico assessment of phytochemical derivatives generated using CHEESE webserver for advancement of druggable candidate in pancreatic cancer therapy. [PDF]

In Silico Pharmacol
Olowosoke CB, Ishabiyi FO, Bouribab A, Munir A, Awoyemi B, Nsofo WN, Christabel AC, Joy JO, Chtita S, Omoboyede V, Chukwuemeka PO.   +10 more
europepmc   +1 more source