, 2012 The KCNH2 gene encodes the Kv11.1 potassium channel that conducts the rapidly activating delayed rectifier current in the heart. KCNH2 pre-mRNA undergoes alternative processing; intron 9 splicing leads to the formation of a functional, full-length Kv11 ...
Gong, Qiuming +2 more
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Stereoselective block of the hERG potassium channel by the Class Ia antiarrhythmic drug disopyramide. [PDF]
Yihong Zhang +5 more
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A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome
Cell, 1995 M. Curran +5 more
semanticscholar +1 more source
Microtubule Dependent Mechanisms Regulate the Trafficking Deficient Phenotype of hERG Mutations Linked to Long QT Syndrome [PDF]
, 2010 Jennifer L. Smith +4 more
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Activation of hERG Channels: Opening New Applications for the Biophysics of Antiarrhythmic Therapy [PDF]
, 2015 Randall L. Rasmusson, Justus Anumonwo
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hERG-Att: Self-attention-based deep neural network for predicting hERG blockers
Comput. Biol. Chem., 2020 Hyunho Kim, Hojung Nam
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Protein Kinase A Activity at the Endoplasmic Reticulum Surface Is Responsible for Augmentation of Human ether-a-go-go-related Gene Product (HERG) [PDF]
, 2011 Jakub Sroubek, Thomas V. McDonald
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KCNH2-L693P Causes Long QT Syndrome Type 2 Through hERG Channel Dysfunction: Functional Validation of a Variant of Uncertain Significance. [PDF]
Mol Genet Genomic MedZheng XF +4 more
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Relevance of the proximal domain in the amino‐terminus of HERG channels for regulation by a phospholipase C‐coupled hormone receptor [PDF]
, 2003 David Gómez‐Varela +7 more
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