Upregulation of SOCS-3 and PIAS-3 impairs IL-12-mediated interferon-gamma response in CD56 T cells in HCV-infected heroin users. [PDF]
PLoS ONE, 2010 CD56(+) T cells are abundant in liver and play an important role in host innate immunity against viral infections, including hepatitis C virus (HCV) infection, a common infection among heroin abusers. We thus investigated the in vivo impact of heroin use
Li Ye +5 more
doaj +1 more source
The societal cost of heroin use disorder in the United States. [PDF]
PLoS ONE, 2017 Heroin use in the United States has reached epidemic proportions. The objective of this paper is to estimate the annual societal cost of heroin use disorder in the United States in 2015 US dollars.An analytic model was created that included incarceration
Ruixuan Jiang +3 more
doaj +1 more source
Some cognitive transformations about the dynamics of desistance
Criminology &Public Policy, Volume 21, Issue 4, Page 787-809, November 2022., 2022 Abstract This article explores the role of cognitive transformations in the process of desistance from crime. Based on our own and others’ subsequent research, clearly, some aspects of our initial theorizing warrant revisiting and adjustment. The discussion describes changes to ideas about the sequencing of various types of cognitive shifts, suggests ...
Peggy C. Giordano
wiley +1 more source
Toots, tastes and tester shots: user accounts of drug sampling methods for gauging heroin potency
Harm Reduction Journal, 2018 Background Internationally, overdose is the primary cause of death among people injecting drugs. However, since 2001, heroin-related overdose deaths in the United States (US) have risen sixfold, paralleled by a rise in the death rate attributed to ...
Sarah G. Mars +2 more
doaj +1 more source
Postmortem tissue distribution of morphine and its metabolites in a series of heroin related deaths [PDF]
, 2018 The abuse of heroin (diamorphine) and heroin deaths are growing around the world. The interpretation of the toxicological results from suspected heroin deaths is notoriously difficult especially in cases where there may be limited samples.
Beer, Lewis J. +6 more
core +4 more sources
Family Related Factors and Concurrent Heroin Use in Methadone Maintenance Treatment in China. [PDF]
, 2018 BackgroundThe use of heroin during Methadone Maintenance Treatment (MMT) is a challenging problem that contributes to poor treatment outcomes. Families may play an important role in addressing concurrent heroin use during MMT, especially in collectivist ...
Feng, Nan +4 more
core +1 more source
Heroin addiction: the past and future [PDF]
, 2008 Substance misuse, in particular heroin addiction contributes to health and social problems. Although effective medical treatment was available, earlier efforts confined the treatment of heroin addicts to in-house rehabilitation which required them to be ...
AR, Rusdi +3 more
core +1 more source
Reduction in cerebral perfusion after heroin administration: a resting state arterial spin labeling study. [PDF]
PLoS ONE, 2013 Heroin dependence is a chronic relapsing brain disorder, characterized by the compulsion to seek and use heroin. Heroin itself has a strong potential to produce subjective experiences characterized by intense euphoria, relaxation and release from craving.
Niklaus Denier +8 more
doaj +1 more source
Chasing the dragon – an overview of heroin trafficking [PDF]
, 2016 There are many problems encountered during the attempt to tackle the heroin trade on a global level. Afghanistan is largely responsible for the production of heroin, providing a global distribution amount of 75%.
Carvetta, CA, O'Hagan, A
core +1 more source
Ranking the harm of non-medically used prescription opioids in the UK [PDF]
, 2015 A panel of nine experts applied multi-criteria decision analysis (MCDA) to determine the relative overall harm to users and harms to others of street heroin (injected and smoked) and eleven non-medically used prescription opioids.
Bell, James +11 more
core +4 more sources