Results 11 to 20 of about 22,299 (230)
Opioid Receptors Gene Polymorphism and Heroin Dependence in Iran [PDF]
Basic and Clinical Neuroscience, 2018 Introduction: Genes often have multiple polymorphisms that interact with each other and the environment in different individuals. Variability in the opioid receptors can influence opiate withdrawal and dependence.
Sara Soleimani Asl +7 more
doaj +2 more sources
Chronic Heroin Dependence Leading to Adrenal Insufficiency [PDF]
Case Reports in Endocrinology, 2014 Opioids have been the mainstay for pain relief and palliation over a long period of time. They are commonly abused by drug addicts and such dependence usually imparts severe physiologic effects on multiple organ systems. The negative impact of opioids on
Gautam Das
doaj +2 more sources
Effect of PDYN rs2281285, rs2235749 and rs910080 gene polymorphisms on the intensity of depression symptoms and negative craving in heroin addicts [PDF]
Archives of Biological Sciences, 2021 The present study was undertaken to explore whether prodynorphin (PDYN) polymorphisms have an effect on the intensity of depressive symptoms and negative craving in heroin addicts in a sample of 100 heroin addicts and 108 controls.
Kaya-Akyüzlü Dilek +3 more
doaj +1 more source
Opium dependence and the potential impact of changes in treatment coverage level: A dynamic modeling study [PDF]
Health Promotion Perspectives, 2021 Background: The most common drug, illegally used in Iran is opium. The treatment of people with substance use disorder is one of the most important strategies in reducing its burden.
Hosein Rafiemanesh +8 more
doaj +1 more source
The Effect of Drug Abstinence Program on Memory Functioning of Heroin Addicts [PDF]
International Journal of Travel Medicine and Global Health, 2015 Introduction: Most of our knowledge regarding the link between opioid dependence and poor cognitive functioning is derived from cross sectional studies.This longitudinal study measured the change in memory functioning following complete abstinence among ...
Sepideh Aryanfard +5 more
doaj +1 more source
Heroin maintenance for chronic heroin-dependent individuals [PDF]
Cochrane Database of Systematic Reviews, 2010 Several types of medications have been used for stabilizing heroin users: Methadone, Buprenorphine and levo-alpha-acetyl-methadol (LAAM.) The present review focuses on the prescription of heroin to heroin-dependent individuals.To compare heroin maintenance to methadone or other substitution treatments for opioid dependence regarding: efficacy and ...
Marica, Ferri +2 more
openaire +3 more sources
Indian Journal of Psychiatry, 2021 Background: Craving is the subjective experience of desire for specific drugs. Lack of reliability and untested construct validity are limiting factors for the existing questionnaires to assess craving.
Shantanu Shukla +4 more
doaj +1 more source
Pathways to age of onset of heroin use: a structural model approach exploring the relationship of the COMT gene, impulsivity and childhood trauma. [PDF]
PLoS ONE, 2012 The interaction of the association of dopamine genes, impulsivity and childhood trauma with substance abuse remains unclear.To clarify the impacts and the interactions of the Catechol -O-methyltransferase (COMT) gene, impulsivity and childhood trauma on ...
Ting Li +8 more
doaj +1 more source
Elderly male with late-onset heroin dependence
Journal of Geriatric Mental Health, 2021 Substance use disorders usually have their onset during the adolescent period. However, in rare cases environmental and psychosocial factors can contribute toward a later onset.
Akansha Bhardwaj +3 more
doaj +1 more source
EClinicalMedicine, 2019 Background: Heroin is currently contributing to the worst drug addiction epidemic in United States history; recent rates of use, dependence and death have also increased dramatically in parts of Europe.
Christina Marel +5 more
doaj +1 more source