EClinicalMedicine, 2019 Background: Heroin is currently contributing to the worst drug addiction epidemic in United States history; recent rates of use, dependence and death have also increased dramatically in parts of Europe.
Christina Marel +5 more
doaj +1 more source
Narcotics Addiction and Its Treatment [PDF]
, 1957 The ongoing mythologizing of the poet in both criticism and, as recently in a play produced by Wasa teater (Vasa), is reductive, and needs to be confronted.
Winick, Charles
core +4 more sources
Brain Sciences, 2012 Opiate withdrawal is followed by a protracted abstinence syndrome consisting of craving and physiological changes. However, few studies have been dedicated to both the characterization and understanding of these long-term alterations in post-dependent ...
Luis Stinus +2 more
doaj +1 more source
Pathological regional blood flow in opiate-dependent patients during withdrawal: A HMPAO-SPECT study [PDF]
, 1998 The aims of the present study were to investigate regional cerebral blood flow (rCBF) in heroin-dependent patients during withdrawal and to assess the relation between these changes and duration of heroin consumption and withdrawal data.
Biersack, H. J. +9 more
core +1 more source
Enlarged cerebrospinal fluid spaces in opiate-dependent male patients: A stereological CT study [PDF]
, 1998 Computed tomography was performed in 9 male patients with a diagnosis of opiate dependence and in 9 age-matched psychiatric controls (neurotic depression).
Broich, Karl +7 more
core +1 more source
Medical diagnoses associated with substance dependence among inpatients at a large urban hospital. [PDF]
PLoS ONE, 2015 There are limited data on reasons for hospital admission among patients dependent on substances other than alcohol. We compared primary discharge diagnoses for heroin- or cocaine-dependent patients to non-dependent patients.We evaluated a cohort of ...
Humberto Choi +3 more
doaj +1 more source
The newer opioid agonist treatment with lower substitutive opiate doses is associated with better toxicology outcome than the older harm reduction treatment [PDF]
, 2016 Background: Charge-free heroin use disorder treatment in Italy follows two main approaches, i.e., harm reduction treatment (HRT) strategy in community low-threshold facilities for drug addiction and opioid agonist treatment (OAT) in high-threshold ...
Bacciardi, Silvia +8 more
core +1 more source
The Leeds Evaluation of Efficacy of Detoxification Study (LEEDS) project: An open-label pragmatic randomised control trial comparing the efficacy of differing therapeutic agents for primary care detoxification from either street heroin or methadone [ISRCTN07752728] [PDF]
, 2004 BACKGROUND: Heroin is a synthetic opioid with an extensive illicit market leading to large numbers of people becoming addicted. Heroin users often present to community treatment services requesting detoxification and in the UK various agents are used ...
A Ritter +22 more
core +3 more sources
Frontal Metabolite Concentration Deficits in Opiate Dependence Relate to Substance Use, Cognition, and Self-Regulation. [PDF]
, 2016 ObjectiveProton magnetic resonance spectroscopy (1H MRS) in opiate dependence showed abnormalities in neuronal viability and glutamate concentration in the anterior cingulate cortex (ACC).
Abé, Christoph +5 more
core +1 more source
Treatment of heroin dependence with ibogaine
European Psychiatry, 2016 BackgroundThe use of the hallucinogen ibogaine as an anti-addiction agent has been described in several case reports, dating back to the eighties. The anti-addiction properties of ibogaine have been confirmed in a large body of animal work. Ibogaine has been shown to be effective in reducing withdrawal severity and substance use for a variety of ...
Schellekens, A.F.A. +4 more
openaire +3 more sources