Results 171 to 180 of about 269,557 (334)

Newly identified properties of known pharmaceuticals and myxobacterial small molecules revealed by screening for autophagy modulators

open access: yesThe FEBS Journal, EarlyView.
Autophagy is a cellular degradation process involved in, for example, immune responses to pathogens and neurodegeneration. To identify modulators of autophagy, we developed a microscopy‐based screening assay and identified previously unknown autophagy‐modulating activities in known drugs and natural products from myxobacteria and fungi.
Janine Fichtner   +13 more
wiley   +1 more source

Mucus-Penetrating Nanoparticles for Vaginal Drug Delivery Protect Against Herpes Simplex Virus

open access: green, 2012
Laura M. Ensign   +6 more
openalex   +2 more sources

Differential regulation of translational stress responses by herpesvirus ubiquitin deconjugases

open access: yesThe FEBS Journal, EarlyView.
Translating viral mRNAs is challenging due to structural features that may slow translation or induce ribosome stalling. The viral ubiquitin deconjugases encoded by human pathogenic herpesviruses regulate the cellular response to ribosomal stress by inhibiting various branches of the Ribosomal Quality Control (RQC) and activating Ribosomal Stress ...
Jiangnan Liu   +3 more
wiley   +1 more source

Temporal network analysis of comorbidities among people with HIV in South Carolina

open access: yesHIV Medicine, EarlyView.
Abstract Introduction People with HIV experience a high rate of comorbidities that can complicate their health outcomes. Understanding the prevalence, interrelationships and temporal development of these comorbidities is crucial for improving health management and quality of life for people with HIV.
Yunqing Ma   +6 more
wiley   +1 more source

Herpes Simplex (Herpes Febrilis)

open access: yesInternational Journal of Clinical Practice, 1965
openaire   +2 more sources

Late diagnosis of paediatric HIV infection in high‐income countries: Lessons from the HIV Perinatal Virtual Clinic

open access: yesHIV Medicine, EarlyView.
Abstract Introduction Timely diagnosis of HIV in children remains a challenge in all settings including low‐prevalence, high‐income countries (HIC). We aimed to characterize the prevalence of late diagnosis, and prior missed diagnostic opportunities among new presentations of paediatric HIV in HIC referred to an international Perinatal Virtual Clinic ...
Carolina Curto   +8 more
wiley   +1 more source

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