Results 191 to 200 of about 269,557 (334)

Exploring the psychiatric spectrum of herpes simplex virus encephalitis. [PDF]

Indian J Psychiatry
Haritha S, Thomas SP, Geo J.
europepmc   +1 more source

Coupling of both a transactivation module and a double‐stranded DNA‐binding domain boosts Cas12i3 variant‐based cytosine and adenine editing in plants

Journal of Integrative Plant Biology, EarlyView.
Fusions of a transactivation module and a double‐stranded DNA‐binding domain produced effective Cas12i3 variant‐based cytosine and adenine base editors, with improved C‐to‐T and A‐to‐G base editing efficiency and expanded editing window. Generated herbicide‐resistant rice germplasm by using these base editors demonstrates their potential for precise ...
Chen Zhang, Jingying Li, Yucai Li, Lei Yan, Christina Seok Yien Yong, Shaoya Li, Yubing He, Lanqin Xia   +7 more
wiley   +1 more source

Gene therapy for epilepsy: An emerging, promising approach for a serious neurological disorder

Journal of Internal Medicine, EarlyView.
Abstract Gene therapy is emerging as a groundbreaking strategy for treating epilepsy, offering new hope to patients who do not respond to conventional medications. Despite advancements in anti‐seizure treatments, nearly 30%–40% of individuals with epilepsy continue to experience uncontrolled seizures, highlighting the urgent need for more effective and
Marco Ledri, Merab Kokaia
wiley   +1 more source

Partial inhibition of viral replication machinery enhances recombination in herpes simplex viruses. [PDF]

Biol Direct
Ralph-Altman M, Avhar D, Altman Y, Cohen I, Azulay H, Korner T, Sweed S, Tomer E, Kobiler O.   +8 more
europepmc   +1 more source

The dysregulation of innate immunity by Porphyromonas gingivalis in the etiology of Alzheimer's disease

Journal of Internal Medicine, EarlyView.
Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron, Jennifer S. Lin, Mark I. Ryder, Peter Bergman   +3 more
wiley   +1 more source

Fixed drug eruption misdiagnosed as herpes simplex virus infection. [PDF]

Can Fam Physician
Moschella A, Gifford F.
europepmc   +1 more source

Characteristics of Acyclovir‐Resistant Herpes Simplex Virus Infection in Hematological Patients

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Objective Acyclovir‐resistant herpes simplex virus infections pose a significant challenge in immunosuppressed patients. This study aimed to characterize the clinical features, treatment outcomes, and mortality associated with acyclovir‐resistant herpes simplex virus infection. Materials and Methods A retrospective analysis was conducted on 18
Reema Shehadeh, Mor Bar Ilan, Sara Dovrat, Ronit Yerushalmi, Michal Tepperberg Oikawa, Evangelia Piperi, Nikolaos G. Nikitakis, Noam Yarom   +7 more
wiley   +1 more source

Herpes simplex virus type 2 implicated in a case of acute disseminated encephalomyelitis. [PDF]

Access Microbiol
Booth S, Starinskij I, Gallacher S, Garmany P.   +3 more
europepmc   +1 more source

Hammersmith Infant Neurological Examination at 3 Months in Infants at Risk for Congenital Infections: A Cohort Study

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Introduction STORCH refers to a group of congenital infections (syphilis, toxoplasmosis, rubella, cytomegalovirus and herpes) that can impact the central nervous system. As clinical signs may not appear until several months or years after birth, the early detection of risk in STORCH‐exposed infants has been challenging, and the use of ...
Karen Cristine Oliveira de Azambuja, Amanda de Arguelho Oliveira Arguelho, Meyene Duque Weber, Lorrainy Marques da Silva Dutra, Tathiana Ghisi de Souza, Daniele Soares‐Marangoni   +5 more
wiley   +1 more source

Herpes Vegetans: An Atypical Presentation of Herpes Simplex Virus (HSV) in AIDS. [PDF]

Cureus
Alfieri GR, Audino E, Diaz A.
europepmc   +1 more source