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Pioneer factors in viral infection
Frontiers in Immunology, 2023 Pioneer factors are transcription factors sharing the fascinating ability to bind to compact chromatin and thereby alter its transcriptional fate. Most pioneer factors are known for their importance during embryonic development, for instance, in inducing
Eva Neugebauer +9 more
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Pathogenesis and virulence of herpes simplex virus
Virulence, 2021 Two of the most prevalent human viruses worldwide, herpes simplex virus type 1 and type 2 (HSV-1 and HSV-2, respectively), cause a variety of diseases, including cold sores, genital herpes, herpes stromal keratitis, meningitis and encephalitis.
Shuyong Zhu, A. Viejo-Borbolla
semanticscholar +1 more source
Herpes Simplex Virus Cell Entry Mechanisms: An Update
Frontiers in Cellular and Infection Microbiology, 2021 Herpes simplex virus (HSV) can infect a broad host range and cause mild to life threating infections in humans. The surface glycoproteins of HSV are evolutionarily conserved and show an extraordinary ability to bind more than one receptor on the host ...
Krishnaraju Madavaraju +4 more
semanticscholar +1 more source
Seroprevalence of Herpes Simplex Virus type-1antibodies (IgM,IgG) in smokers in Kirkuk city-Iraq
Tikrit Journal of Pure Science, 2023 Herpes Simplex Virus type-1 (HSV-1) is classified in the α-herpes virus group of the Herpesviridae and HSV-1 infections are very common in the human population. The objective of this study is to determine the prevalence of anti-herpes simplex virus type-
Lezan Medhat Mohammed Zangana
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Herpes simplex virus: global infection prevalence and incidence estimates, 2016
Bulletin of the World Health Organization, 2020 Objective To generate global and regional estimates for the prevalence and incidence of herpes simplex virus (HSV) type 1 and type 2 infection for 2016.
Charlotte James +6 more
semanticscholar +1 more source
Relationship Between Pemphigus Vulgaris Severity and PCR-positive Herpes Simplex Virus
Acta Dermato-Venereologica, 2022 Pemphigus vulgaris is a rare autoimmune skin disease. Although herpes simplex virus has been associated with autoimmune diseases, evidence regarding its association with pemphigus vulgaris exacerbations is scarce. This retrospective cohort study aimed to
Sharon Baum +7 more
doaj +1 more source
HSV-1 genome subnuclear positioning and associations with host-cell PML-NBs and centromeres regulate LAT locus transcription during latency in neurons. [PDF]
, 2012 Major human pathologies are caused by nuclear replicative viruses establishing life-long latent infection in their host. During latency the genomes of these viruses are intimately interacting with the cell nucleus environment.
Catez, Frédéric +8 more
core +13 more sources
Intervirology, 1997 CNS infections caused by human herpesvirus 1 and human herpesvirus 2-herpes simplex virus type 1 and herpes simplex virus type 2--are reviewed. The major diseases associated with these viruses are meningitis and encephalitis. Two forms of encephalitis are known, neonatal encephalitis and encephalitis occurring after the neonatal period.
Klapper, P. E., Cleator, G. M.
openaire +3 more sources
Brazilian Journal of Infectious Diseases, 2014 The aim of this study was to evaluate the use of RNA interference to inhibit herpes simplex virus type-1 replication in vitro. For herpes simplex virus type-1 gene silencing, three different small interfering RNAs (siRNAs) targeting the herpes simplex ...
Amanda Perse da Silva +2 more
doaj +1 more source
Regulation of alphaherpesvirus infections by the ICP0 family of proteins [PDF]
, 2013 Immediate-early protein ICP0 of herpes simplex virus type 1 (HSV-1) is important for the regulation of lytic and latent viral infection. Like the related proteins expressed by other alphaherpesviruses, ICP0 has a zinc-stabilized RING finger domain that ...
Boutell, Chris, Everett, Roger
core +1 more source