Results 161 to 170 of about 116,364,761 (277)
MyD88‐Family Adaptors: Compartmentalised Signalling and Non‐Immune Functions
MyD88‐family adaptors coordinate receptor‐ and compartment‐specific innate immune signalling across plasma membrane and endosomal pathways. At the plasma membrane, TIRAP/MAL supports MyD88‐dependent signalling downstream of TLR2 and TLR4, whereas endosomal TLR7, TLR8 and TLR9 recruit MyD88 directly.
Seshu Vardhan Pothabathula +6 more
wiley +1 more source
Development of a HiFi-LAMP assay for the detection of herpes simplex virus type 1. [PDF]
Wang Z +7 more
europepmc +1 more source
OZAWA, Shigeru +4 more
openaire +3 more sources
Advanced Materials for Biologics Delivery to Brain Tumors
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
Acute Expressive Aphasia and Confusion As the Initial Neurologic Manifestation of Herpes Simplex Virus Type 1 Encephalitis. [PDF]
Espinal V +4 more
europepmc +1 more source
ABSTRACT Objectives Explore the relationship between maternal SARS‐CoV‐2 infection and congenital anomalies in Wales. Study Design Mixed observational epidemiological cross‐sectional and cohort. Methods Congenital anomaly prevalence data were provided by the Congenital Anomaly Register and Information Service. Two comparisons were made using these data:
Samantha Rose Fisher +4 more
wiley +1 more source
Association of Herpes Simplex Virus Type-1 With Dementia Outcomes: Longitudinal Retrospective Cohort Study Using Real-World Electronic Health Record Data. [PDF]
Islam MM +5 more
europepmc +1 more source
ABSTRACT Recurrent facial nerve palsy, particularly when alternating sides and accompanied by orofacial edema, should raise suspicion for Melkersson–Rosenthal syndrome. Recognition of fissured tongue as part of the clinical triad may facilitate timely diagnosis, avoid unnecessary investigations, and enable appropriate corticosteroid treatment.
Zoran Dudvarski +6 more
wiley +1 more source
The cell-mediated adaptive immune response to herpes simplex virus type 1 encephalitis: mechanisms and clinical implications. [PDF]
Osborne L +6 more
europepmc +1 more source
The herpes simplex virus type 1 replisome
The Herpes Simplex virus replisomeIn Herpes Simplex virus type 1, HSV-1, six viral proteins form a multiprotein machine, replisome, which is responsible for the bulk of viral DNA replication. Our understanding of the molecular mechanisms of HSV-1 replisome function has been hampered by the lack of an in vitro DNA replication system.
openaire +1 more source

