Results 181 to 190 of about 116,364,761 (277)

Early Remission of Cerebrospinal Fluid Interleukin‐6 After Initial Immunotherapy Predicts a Good Prognosis in Autoimmune Encephalitis

open access: yesNeurology and Clinical Neuroscience, Volume 14, Issue 6, Page 469-477, November 2026.
ABSTRACT Background Autoimmune encephalitis therapy requires adjusting the regimen based on therapeutic response; however, clinical indicators of this response remain unknown. Aim To determine the predictive capability of cerebrospinal fluid (CSF), electroencephalography (EEG), and brain magnetic resonance imaging (MRI) in identifying responders to ...
Yuta Madokoro   +8 more
wiley   +1 more source

Herpes simplex virus type 1 interferes with signal transducer and activator of transcription 3 expression in infected mature dendritic cells. [PDF]

open access: yesJ Gen Virol
Birzer A   +7 more
europepmc   +1 more source

Systems Pharmacology Investigation of Phytochemicals From Scilla peruviana L.: Integrated Gas Chromatography–Mass Spectrometry Profiling, Network Pharmacology, and Molecular Docking Reveal Potential Anti‐Inflammatory Mechanisms

open access: yesChemistryOpen, Volume 15, Issue 11, November 2026.
This study aims to characterize the volatile and fatty acid constituents of Scilla peruviana and investigate their potential anti‐inflammatory mechanisms. Volatile compounds are identified by headspace solid‐phase microextraction (HS‐SPME) coupled with GC–MS, whereas fatty acids are analyzed by GC–MS following derivatization.
Roukia Zatout   +2 more
wiley   +1 more source

Herpes simplex virus type 1 R-loops are targets for APOBEC-mediated mutagenesis. [PDF]

open access: yesGenome Biol
Miskei M   +12 more
europepmc   +1 more source

Pharmacological and Therapeutic Potential of Garlic (Allium sativum): Integrating Phytochemistry, Molecular Mechanisms, and Clinical and Preclinical Evidence

open access: yesChemistryOpen, Volume 15, Issue 11, November 2026.
Garlic bioactive compounds, including organosulfur compounds (allicin, DADS, DATS, and SAC), phenolic compounds, and quercetin, regulate the Nrf2/HO‐1, NF‐κB, PI3K/Akt, and AMPK/eNOS signaling pathways. These actions enhance antioxidant defenses, suppress inflammation, improve metabolic and cardiovascular function, and contribute to reduced blood ...
Gudisa Bereda
wiley   +1 more source

Continuous Intravenous Acyclovir as Outpatient Parenteral Antimicrobial Therapy for HSV and VZV Neurological Infections: A Case Series With Pharmacokinetic and Cost Evaluation, and Review of Literature

open access: yesReviews in Medical Virology, Volume 36, Issue 6, November 2026.
ABSTRACT Varicella zoster virus (VZV) and herpes simplex virus (HSV) are major causes of viral meningitis and encephalitis. Standard intermittent intravenous acyclovir requires hospitalisation, reducing patient comfort and prolonging admissions. Continuous infusion may maintain therapeutic plasma and cerebrospinal fluid (CSF) concentrations while ...
Irene G. Manders   +7 more
wiley   +1 more source

Multiple Sclerosis and Viruses: « Liaisons Dangereuses »

open access: yesReviews in Medical Virology, Volume 36, Issue 6, November 2026.
ABSTRACT Multiple sclerosis (MS) is a complex, multifactorial neurodegenerative disease with an aetiology that is still partially elusive. Several risk factors are associated with MS development including genetic predisposition and various environmental stressors; however, recently, viral infections have gained significant attention as a crucial ...
Samanta Plavina   +11 more
wiley   +1 more source

Significance of Systemic Immune‐Inflammation and Inflammatory Response Indices in Vestibular Neuritis

open access: yesClinical Otolaryngology, Volume 51, Issue 6, Page 855-860, November 2026.
ABSTRACT Introduction This study investigated the relationship between vestibular neuritis and various systemic inflammatory indices—namely, neutrophil‐to‐lymphocyte ratio (NLR), platelet‐to‐lymphocyte ratio (PLR), monocyte‐to‐lymphocyte ratio (MLR), systemic immune‐inflammation index (SII), and systemic inflammation response index (SIRI) and the ...
Tuğba Tulacı   +7 more
wiley   +1 more source

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