Results 191 to 200 of about 116,364,761 (277)

EEG-motor correlation as early Alzheimer's disease index in herpes simplex virus type-1-infected mice. [PDF]

open access: yesBrain Commun
D'Amelio C   +20 more
europepmc   +1 more source

Advances in Cytosolic dsRNA Sensing of Viral Infections

open access: yesImmunology &Cell Biology, Volume 104, Issue 10, Page 975-986, November‐December 2026.
Activation of cytosolic dsRNA sensors by viral infection generates multiple outcomes. dsRNA generated during viral infection, either of viral origin or from endogenous sources, can activate multiple cytosolic dsRNA sensors. Activation of PKR critically induces protein translation shutdown via phosphorylation of eukaryotic translation initiation factor ...
Sofia Maceratessi, Natalia G. Sampaio
wiley   +1 more source

Interleukin‐12: Central Roles in Immune Regulation and Disease Therapy

open access: yesImmunology &Cell Biology, Volume 104, Issue 10, Page 996-1014, November‐December 2026.
IL‐12 levels are tightly regulated to balance effective protective immunity against infections and cancer with the risk of excessive inflammation and autoimmune disease. Both insufficient and excessive IL‐12 activity can therefore be detrimental, highlighting the importance of precisely controlling its production and signaling. ABSTRACT Interleukin‐12 (
Anthi Psoma, Geert van den Bogaart
wiley   +1 more source

Bacteriophage P22 Virus‐Like Particles as Nanoscale Protein Scaffolds for Plant Synthetic Biology

open access: yesPlant Biotechnology Journal, Volume 24, Issue 11, Page 5671-5683, November 2026.
ABSTRACT Advancing the utility of plant synthetic biology requires the continued development of protein engineering tools. Self‐assembling protein compartments, such as virus‐like particles (VLPs), provide versatile scaffolds for synthetic biology. However, few plant‐expressed VLPs have demonstrated broad amenability to protein engineering, restricting
Maxim D. Harding   +5 more
wiley   +1 more source

Risk Assessment of an Illegal Laboratory in Reedley, California, Using Geospatial Analysis of Open‐Source Epidemic Intelligence Data

open access: yesRisk Analysis, Volume 46, Issue 11, November 2026.
ABSTRACT An illegal laboratory discovered in Reedley, California, in December 2022 was in a warehouse, operating without a license, handling about a thousand transgenic mice, chemicals, and possibly over 20 pathogens, including vials labeled Ebola, which were never tested but destroyed.
Atalay Goshu Muluneh   +7 more
wiley   +1 more source

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