Results 21 to 30 of about 116,364,761 (277)
Medicina Universitaria, 2022 Diabetic ketoacidosis is a life-threatening acute complication of type-1 diabetes mellitus. It is most frequently precipitated by bacterial infections, although viral pathogens should always be considered.
Victoria A. Ahuett-Lopez +3 more
doaj +1 more source
Brazilian Journal of Infectious Diseases, 2014 The aim of this study was to evaluate the use of RNA interference to inhibit herpes simplex virus type-1 replication in vitro. For herpes simplex virus type-1 gene silencing, three different small interfering RNAs (siRNAs) targeting the herpes simplex ...
Amanda Perse da Silva +2 more
doaj +1 more source
Herpes simplex virus type 2: epidemiology and management options in developing countries [PDF]
, 2007 Genital herpes simplex virus type 2 (HSV2) is highly prevalent worldwide and an increasingly important cause of genital ulcer disease (GUD). Continued HSV2 transmission is facilitated by the large number of undiagnosed cases, the frequency of atypical ...
Geretti, AM +7 more
core +1 more source
Seroprevalence of Herpes Simplex Virus Type 1 and Type 2 among Egyptian Children Aged from One to 15 Years old: A Comparative Study [PDF]
Afro-Egyptian Journal of Infectious and Endemic Diseases, 2022 Background and study aim: Recent research has highlighted the importance of monitoring trends in herpes simplex virus 1 (HSV-1) and herpes simplex virus 2 (HSV-2) seroprevalence and their etiological surveillance.
Mahmoud El-Ansary
doaj +1 more source
A tail-like assembly at the portal vertex in intact herpes simplex type-1 virions [PDF]
, 2012 Herpes viruses are prevalent and well characterized human pathogens. Despite extensive study, much remains to be learned about the structure of the genome packaging and release machinery in the capsids of these large and complex double-stranded DNA ...
Rixon Frazer J. +23 more
core +1 more source
Activation of the Herpes Simplex Virus Type 1 Protease [PDF]
Journal of Biological Chemistry, 1995 The catalytic efficiency of the mature HSV-1 protease has been examined as a function of solvent composition. With the peptide substrate HTYLQASEKFKMWG-amide, the specificity constant (kcat/Km) at pH 7.5 for cleavage is 5.2 M-1 s-1. This value increases to 38 M-1 s-1 when 25% glycerol is present in the reaction mixture.
D L, Hall, P L, Darke
openaire +2 more sources
Entry pathways of herpes simplex virus type 1 into human keratinocytes are dynamin- and cholesterol-dependent [PDF]
, 2011 Herpes simplex virus type 1 (HSV-1) can enter cells via endocytic pathways or direct fusion at the plasma membrane depending on the cell line and receptor(s).
Mei-Ju Hsu +16 more
core +1 more source
Journal of Medical Case Reports, 2011 Introduction Herpes simplex virus type 1 encephalitis presents acutely in patients who are immunocompetent. We report what we believe to be the first published case of a subacute course of herpes simplex virus type 1 encephalitis in a patient with ...
Corman Lourdes C, Singhal Rashi L
doaj +1 more source
Mechanisms of herpes simplex virus type 1 reactivation [PDF]
Journal of Virology, 1996 Primary cultures of trigeminal ganglion (TG) cells from herpes simplex virus type 1 (HSV-1) latently infected mice were used to study reactivation. Expression of HSV-1 latency-associated transcripts was noted in TG cell cultures. Infectious virus appeared in 75% of culture supernatants within 120 h after heat stress.
W P, Halford, B M, Gebhardt, D J, Carr
openaire +2 more sources
Herpes simplex virus triggers and then disarms a host antiviral response [PDF]
, 2001 Virus infection induces an antiviral response that is predominantly associated with the synthesis and secretion of soluble interferon. Here, we report that herpes simplex virus type 1 virions induce an interferon-independent antiviral state in human ...
Smiley, J R +5 more
core +1 more source