Results 51 to 60 of about 170,851 (306)
Cellular v-ATPase is required for virion assembly compartment formation in human cytomegalovirus infection [PDF]
Open Biology, 2017 Successful generation of virions from infected cells is a complex process requiring orchestrated regulation of host and viral genes. Cells infected with human cytomegalovirus (HCMV) undergo a dramatic reorganization of membrane organelles resulting in ...
Jonathan Pavelin +5 more
doaj +1 more source
The suppression of apoptosis by α-herpesvirus
Cell Death and Disease, 2017 Apoptosis, an important innate immune mechanism that eliminates pathogen-infected cells, is primarily triggered by two signalling pathways: the death receptor pathway and the mitochondria-mediated pathway.
Yu You +11 more
semanticscholar +1 more source
Advanced Therapeutics, EarlyView.Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi +5 more
wiley +1 more source
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2009 Relata-se um caso de meningoencefalite causada por Herpesvirus bovino 5 (BoHV-5) heritabilityem uma vaca com cinco anos de idade. O animal manifestou quadro clínico inicial de síndrome medular baixa, caracterizada por incoordenação dos membros pélvicos ...
H.M. Aquino Neto +9 more
doaj +1 more source
The Role of microRNAs in the Pathogenesis of Herpesvirus Infection
Viruses, 2016 MicroRNAs (miRNAs) are small non-coding RNAs important in gene regulation. They are able to regulate mRNA translation through base-pair complementarity.
Diogo Piedade, J. M. Azevedo-Pereira
semanticscholar +1 more source
Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives
Advanced Science, EarlyView.Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu +13 more
wiley +1 more source
A pentameric protein ring with novel architecture is required for herpesviral packaging
eLife, 2021 Genome packaging in large double-stranded DNA viruses requires a powerful molecular motor to force the viral genome into nascent capsids, which involves essential accessory factors that are poorly understood.
Allison L Didychuk +5 more
doaj +1 more source
Emerging Infectious Diseases, 2010 The recently designated cyprinid herpesvirus 3 (CyHV-3) is an emerging agent that causes fatal disease in common and koi carp. Since its emergence in the late 1990s, this highly contagious pathogen has caused severe financial losses in common and koi carp culture industries worldwide. In addition to its economic role, recent studies suggest that CyHV-3
Alain Vanderplasschen +4 more
openaire +4 more sources
Structure and Antigenicity of Kaposi's Sarcoma‐Associated Herpesvirus Glycoprotein B
Advanced Science, EarlyView.Kaposi's sarcoma‐associated herpesvirus (KSHV) causes severe cancers without effective treatments. This study presents an atomic model of KSHV's critical infection protein, gB, revealing a unique structure shared with related herpesviruses like Epstein‐Barr virus (EBV). The structural similarity highlights vulnerable targets for antibodies, guiding the
Xin‐Yan Fang +8 more
wiley +1 more source