Identification of an essential virulence gene of cyprinid herpesvirus 3 [PDF]
The genus Cyprinivirus consists of a growing list of phylogenetically related viruses, some of which cause severe economic losses to the aquaculture industry. The archetypal member, cyprinid herpesvirus 3 (CyHV-3) causes mass mortalities worldwide in koi
Boutier, Maxime+5 more
core +2 more sources
Rare Infectious Diseases: Detection and Clinical Implications
Rare infectious diseases are infections that are uncommon, have a low incidence, and are caused by newly emerging pathogens, cross‐species or ectopic infections, or host immunodeficiencies. The detection and diagnosis of rare infections is one of the main reasons for misdiagnosis and missed diagnosis.
Xin Qian+7 more
wiley +1 more source
Equine herpesvirus 1 bridles T lymphocytes to reach its target organs [PDF]
Equine herpesvirus 1 (EHV1) replicates in the respiratory epithelium and disseminates through the body via a cell-associated viremia in leukocytes, despite the presence of neutralizing antibodies. "Hijacked" leukocytes, previously identified as monocytic
Azab, Walid+7 more
core +1 more source
The Essential Co-Option of Uracil-DNA Glycosylases by Herpesviruses Invites Novel Antiviral Design
Vast evolutionary distances separate the known herpesviruses, adapted to colonise specialised cells in predominantly vertebrate hosts. Nevertheless, the distinct herpesvirus families share recognisably related genomic attributes.
Renos Savva
doaj +1 more source
Skin microbiome engineering: Challenges and opportunities in skin diseases treatment
The skin microbiome plays a crucial role in skin health, influencing barrier integrity, immune responses, and disease susceptibility. Various interventions can reshape the microbiome, broadly categorized into targeted and untargeted approaches. Targeted strategies, such as phage therapy, engineered bacteria, and phage lysins, selectively modulate ...
Yiang Lyu, Juntao Shen, You Che, Lei Dai
wiley +1 more source
Glass eels and viruses – a lesson learnt from stocking the eastern German Baltic Sea coast
Abstract Concerns about Anguillid herpesvirus 1 (AngHV‐1) in European eels, especially due to stocking measures, is increasingly coming into focus and raises questions regarding disease monitoring and prevention. In the past, stocking of AngHV‐1‐positive eels into waters assumed AngHV‐1‐free has led to a rapid increase of infected eels in the wild. For
Laura Kullmann+3 more
wiley +1 more source
Speculations on the clinical significance of asymptomatic viral infections [PDF]
A detailed understanding of asymptomatic chronic viral infections is critical to analyse their pathogenesis, assess the severity and burden of disease and, where required, optimize public health control measures.
Gentile, Giuseppe, Micozzi, Alessandra
core +1 more source
An alphaherpesvirus exploits antimicrobial beta-defensins to initiate respiratory tract infection [PDF]
beta-Defensins protect the respiratory tract against the myriad of microbial pathogens entering the airways with each breath. However, this potentially hostile environment is known to serve as a portal of entry for herpesviruses.
Boyen, Filip+8 more
core +2 more sources
Objective To evaluate the value of next⁃generation sequencing (NGS) of cerebrospinal fluid (CSF) in the diagnosis of human herpesvirus encephalitis/meningitis.
Ke JIN+10 more
doaj
CD1d expression and invariant NKT cell responses in herpesvirus infections
Invariant natural killer T (iNKT) cells are a highly conserved subset of unconventional T lymphocytes that express a canonical, semi-invariant T cell receptor (TCR) and surface markers shared with the natural killer cell lineage.
Rusung eTan
doaj +1 more source