Results 11 to 20 of about 13,605 (197)

Investigation of the histopathological level of Ki-67, caspase-3 expressions of the effects of hesperidin on wound healing in the rat esophagus

Acta Cirúrgica Brasileira, 2023
Purpose: The effects of hesperidin application on the wound caused by esophageal burns were investigated in this study. Methods: Wistar albino rats were divided into three groups: Control group: only 1 mL of 0.09% NaCl was administered i.p. for 28 days;
Cemalettin Durgun, Gülsen Kirman, Engin Deveci   +2 more
doaj   +1 more source

Hesperidin plays beneficial roles in disorders associated with the central nervous system: a review

International Journal of Food Properties, 2023
Significant levels of flavonoids with antioxidant properties can be found in citrus species. Flavonoids are a class of plant chemical known for a wide range of pharmacological activities. Notable among these flavonoids is Hesperidin.
Ayomide Victor Atoki, Patrick Maduabuchi Aja, Tijjani Salihu Shinkafi, Erick Nyakundi Ondari, Chinaza Godswill Awuchi   +4 more
doaj   +1 more source

Hesperidin Ameliorates Dexamethasone-Induced Osteoporosis by Inhibiting p53

Frontiers in Cell and Developmental Biology, 2022
Osteoporosis is one of the most frequent skeletal disorders and a major cause of morbidity and mortality in the expanding aging population. Evidence suggests that hesperidin may have a therapeutic impact on osteoporosis.
Meng Zhang, Meng Zhang, Delong Chen, Ning Zeng, Zhendong Liu, Zhendong Liu, Xiao Chen, Xiao Chen, Hefang Xiao, Hefang Xiao, Likang Xiao, Likang Xiao, Zeming Liu, Yonghui Dong, Yonghui Dong, Jia Zheng   +15 more
doaj   +1 more source

The Antidepressant-Like Effects of Hesperidin in Streptozotocin‐Induced Diabetic Rats by Activating Nrf2/ARE/Glyoxalase 1 Pathway

Frontiers in Pharmacology, 2020
The co-occurrence of diabetes and depression is a challenging and underrecognized clinical problem. Alpha-carbonyl aldehydes and their detoxifying enzyme glyoxalase 1 (Glo-1) play vital roles in the pathogenesis of diabetic complications, including ...
Xia Zhu, Haiyan Liu, Yuan Liu, Yajing Chen, Yaowu Liu, Xiaoxing Yin   +5 more
doaj   +1 more source

Hesperidin Anti-Osteoporosis by Regulating Estrogen Signaling Pathways

Molecules, 2023
Osteoporosis (OP) is distinguished by a reduction in bone mass and degradation of bone micro-structure, frequently resulting in fractures. As the geriatric demographic expands, the incidence of affected individuals progressively rises, thereby exerting a
Hong-Yao Hu, Ze-Zhao Zhang, Xiao-Ya Jiang, Tian-Hua Duan, Wei Feng, Xin-Guo Wang   +5 more
doaj   +1 more source

Hesperidin depolarizes the pacemaker potentials through 5-HT4 receptor in murine small intestinal interstitial cells of Cajal

Animal Cells and Systems, 2020
Hesperidin, a citrus flavonoid, can exert numerous beneficial effects on human health. Interstitial cells of Cajal (ICC) are pacemaker cells in the gastrointestinal (GI) tract.
Minwoo Hwang, Jeong Nam Kim, Byung Joo Kim   +2 more
doaj   +1 more source

Insight into the Inhibitory Mechanisms of Hesperidin on α-Glucosidase through Kinetics, Fluorescence Quenching, and Molecular Docking Studies

Foods, 2023
The α-glucosidase inhibitor is of interest to researchers due to its association with type-II diabetes treatment by suppressing postprandial hyperglycemia. Hesperidin is a major flavonoid in orange fruit with diverse biological properties.
Kumaravel Kaliaperumal, Linyan Zhang, Liangliang Gao, Qin Xiong, Yan Liang, Yueming Jiang, Jun Zhang   +6 more
doaj   +1 more source

The flavonoid hesperidin exerts anti-photoaging effect by downregulating matrix metalloproteinase (MMP)-9 expression via mitogen activated protein kinase (MAPK)-dependent signaling pathways

BMC Complementary and Alternative Medicine, 2018
Background Hesperidin is a flavonoid with antioxidant, anti-inflammatory, and immune modulatory activities. Photoaging is a consequence of chronic exposure to the sun and ultraviolet (UV) radiation.
Hee Jeong Lee, A-Rang Im, Su-Man Kim, Hyung-Sik Kang, Jae Dong Lee, Sungwook Chae   +5 more
doaj   +1 more source

A High-Yield Process for Production of Biosugars and Hesperidin from Mandarin Peel Wastes

Molecules, 2020
In this research, novel biorefinery processes for obtaining value-added chemicals such as biosugar and hesperidin from mandarin peel waste (MPW) are described.
Eun Jin Cho, Yoon Gyo Lee, Jihye Chang, Hyeun-Jong Bae   +3 more
doaj   +1 more source

In Vitro study for hesperidin nanoparticles effect on phagocytic activity against Staphylococcus aureus

مجلة مركز بحوث التقنيات الاحيائية, 2018
       Hesperidin is one of the flavonoids from citrus peels and it recognized to possess various biological activities such as, anti-inflammatory, anti-carcinogenic, antioxidant and antimicrobial potentials.
Saja Ali, Ghassan Sulaiman, Mohammed M. Al-Halbosiy   +2 more
doaj   +1 more source