Results 41 to 50 of about 14,514 (211)

Protective Effects of Fenugreek and Stevia Extracts on Dexamethasone‐Induced Testicular Damage in a Rat Model

Food Safety and Health, EarlyView.
Fenugreek and stevia extracts protect against dexamethasone‐induced testicular damage in male rats by enhancing antioxidant defenses, improving sperm quality, and restoring hormonal balance, highlighting their potential as natural therapeutics for preventing corticosteroid‐induced reproductive toxicity.
Mosab Gad, Medhat Ibrahim A. Omar, Mohammed I. Elkhateeb, Ahmed A. Zaky   +3 more
wiley   +1 more source

Effectiveness of hesperidin and rutin on cisplatin-induced testicular dysfunction in rats

Journal of Basic and Applied Zoology
Background Testicular dysfunction is the potential side effects of cisplatin. This investigation aimed to assess the efficacy of hesperidin and rutin on cisplatin-induced testicular dysfunction in rats. Forty adult male rats were divided into: Group (1):
Dina M. I. Heibashy, Wafaa A. Morsy
doaj   +1 more source

Hesperidin Helps Improve the Intestinal Structure, Maintain Barrier Function, and Reduce Inflammation in Yellow-Feathered Broilers Exposed to High Temperatures

Animals
To investigate the possible protective effect of hesperidin on intestinal damage caused by high-temperature heat stress in yellow-feathered broilers, 960 broilers aged 21 days were randomly divided into four groups: HT, HT300, HT450, and HT600, with each
Shaoping He, Guozhi Bian, Yuming Guo, Jiyu Guo   +3 more
doaj   +1 more source

Citrus depressa peel extract and its polymethoxyflavones mitigate acetaminophen‐induced chronic liver injury in mice through antioxidant activation, epigenetic regulation, and gut microbiota modulation

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Preventing chronic liver damage is essential for maintaining overall health and reducing the risk of serious liver diseases. Acetaminophen (APAP) overdose can lead to severe liver damage due to oxidative stress, and citrus fruits are rich in bioactive compounds that may have health benefits.
Po‐Yao Tsai, Zi‐Han Lin, Guor‐Jien Wei, Liang‐Yi Wu, Tien‐Yuan Wu, Yen‐Chen Tung, Ssu‐Han Huang, Zheng‐Yuan Su   +7 more
wiley   +1 more source

Regulation of MAPK by hesperidin.

, 2014
(A) HepG2 cells were untreated or treated with hesperidin for 24 h and whole cell lysate prepared from these cells were subjected to western analysis. Protein level of pERK1/2 and total ERK1/2 are shown relative to the value for untreated control cells. (
Silvia Yumnam (590606), Eun Hee Kim (554740), Gon Sup Kim (590615), Arulkumar Nagappan (590609), Jae Hyeon Cho (590613), Mun Ki Kim (590608), Won Sup Lee (590612), Gyeong Eun Hong (590610), Ho Jeong Lee (590611), Sung Chul Shin (590614), Hyeon Soo Park (590607)   +10 more
core   +1 more source

Metabolomics‐based study of the preservation mechanism of a tea saponin–cinnamaldehyde nanoemulsion applied to Xinyu tangerines

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Background The Xinyu tangerine is a geographical indication agricultural product from Jiangxi province, China. During postharvest storage, nutrient loss and pathogen‐induced decay reduce fruit quality. The selection of appropriate preservatives is therefore important for maintaining postharvest quality.
Yan Leng, Xinjian Gao, Yichen Zhang, Zehang Yan, Wanyi Chen, Yang Huang, Xiaoxia Zuo, Liqin Zhu, Zhipeng Cai, Jing Wang, Yonggen Shen   +10 more
wiley   +1 more source

Soybean induced resistance to Spodoptera eridania herbivory

Pest Management Science, EarlyView.
SOD, CAT, APX, PPO, KTI, and MDA levels were higher in the resistant soybean. S. eridania herbivory increased H2O2 and MDA, but decreased SOD and PPO levels. S. eridania herbivory increased KTI activity only in the resistant variety. Isoquercitrin and daidzin were exclusive to resistant and susceptible soybeans.
Bruno Henrique Sardinha de Souza, Arlindo Leal Boiça Júnior, Durvalina Maria Mathias dos Santos, Moacir Rossi Forim, Antonio Pizolato Neto, Andreísa Fabri Lima, Michael Joseph Stout   +6 more
wiley   +1 more source

Hesperidin increase cytotoxic effect of doxorubicin in MCF-7 cells

, 2016
Hesperidin, a flavonoid, shows strong cytotoxic effect in several cancer cell lines. The aim of this research was to investigate cytotoxic activities of hesperidin alone and in combination with doxorubicin. Cell viability assay of hesperidin, doxorubicin,
Hermawan, Adam; Cancer Chemoprevention Research Center Fakultas Farmasi, Universitas Gadjah Mada
core   +1 more source

Natural Products as Modulators of ABC Transporters in Breast Cancer

Phytotherapy Research, EarlyView.
ABSTRACT Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple‐negative breast cancer (TNBC), continues to hinder effective therapy.
Yoganishalini Sagadevan, Reyhaneh Farghadani, Ammu K. Radhakrishnan   +2 more
wiley   +1 more source

Influence of hesperidin and vitamin C on glycemic parameters, lipid profile, and DNA damage in rats treated with sucrose overload

Anais da Academia Brasileira de Ciências, 2018
We evaluated the influence of hesperidin and vitamin C (VitC) on glycemic parameters, lipid profile, and DNA damage in male Wistar rats treated with sucrose overload.
SILVIA I.R. FRANKE, PATRÍCIA MOLZ, CAMILA MAI, JOEL H. ELLWANGER, FERNANDA F. ZENKNER, JORGE A. HORTA, DANIEL PRÁ   +6 more
doaj   +1 more source