Results 41 to 50 of about 12,133 (118)

In Vitro Evaluation of Cytotoxic and Pro-Apoptotic Effects of Hesperidin Alone and in Combination with Cisplatin on Human Malignant Melanoma Cell Line (A431)

Pharmaceuticals
Background/Objectives: Melanoma is an aggressive skin cancer with high metastatic potential and poor prognosis in advanced stages. Hesperidin, a natural flavonoid, has shown anticancer properties across various malignancies.
Mehmet Uğur Karabat, Mehmet Cudi Tuncer, İlhan Özdemir   +2 more
doaj   +1 more source

First Evidence of the Potential of Postharvest Hesperidin Treatments: Effects on Strawberry Quality During Storage

Foods
Strawberries (Fragaria x ananassa Duch.) are highly perishable fruits that rapidly lose their quality properties, even when stored under cold conditions.
Mihaela Iasmina Madalina Ilea, Huertas María Díaz-Mula, Christian Fernández-Picazo, Pedro Javier Zapata, Alicia Dobón-Suárez, Salvador Castillo, Fabián Guillén   +6 more
doaj   +1 more source

Exploring the impact of hesperidin on probiotic properties of Lactobacillus acidophilus LA-5 and its synbiotic interaction with colon cancer cells

Journal of BioScience and Biotechnology
Probiotics are live microorganisms that provide health benefits to the host when taken in adequate amounts. Hesperidin is a phenolic compound found in banana fruit, lemon fruit, and lemon peel.
Hasan U. Celebioglu, Emre Evin, Sena Davran Bulut, Buse N. Derebasi, Orhan Adali   +4 more
doaj   +1 more source

Chitosan/Hesperidin Nanoparticles for Sufficient, Compatible, Antioxidant, and Antitumor Drug Delivery Systems

Pharmaceuticals
One flavonoid glycoside with demonstrated therapeutic potential for several illnesses, including cancer, is hesperidin. However, because of its limited bioavailability and solubility, it is only marginally absorbed, necessitating a delivery mechanism to ...
May Almukainzi, Thanaa A. El-Masry, Enas I. El Zahaby, Maysa M. F. El-Nagar   +3 more
doaj   +1 more source

Role of hesperidin in modulating antioxidant enzymes in the brain of rats exposed to Nickel Chloride

Phytomedicine Plus
Background: This study aimed to investigate the effects of hesperidin on the gene expression of antioxidant enzymes catalase (Cat), superoxide dismutase (Sod), and glutathione peroxidase (Gpx) in the brain and their enzymatic activities in the brain and ...
Niloufar Alizadeh, Bagher Seyedalipour, Mohammad Karimian   +2 more
doaj   +1 more source

New insights into therapeutic applications and nanoformulation approaches of hesperidin: An updated review

Pharmacological Research - Modern Chinese Medicine
Introduction: Hesperidin is a flavanone glycoside occurring in high levels in citrus species. It is among the most significant natural anti-oxidants employed often in pharmaceuticals for therapeutic applications due to its preventive characteristics ...
Keshav Bansal, Hemant Bhati, Vanshita, Meenakshi Bajpai   +3 more
doaj   +1 more source

Hesperidin as an Emerging Nutraceutical for Management of Diverse Metabolic Syndrome: A Narrative Review on and Experiments

Natural Product Communications
Hesperidin, a flavonoid predominantly found in citrus fruits, has gained attention as a potential nutraceutical for managing various components of metabolic syndrome, including obesity, hypertension, dyslipidemia, and insulin resistance. This review aims
Patrick Maduabuchi Aja, Celestine Obinna Ogbu, Peter Chinedu Agu, Boniface Anthony Ale, Francisca Chidimma Nwiziogo, Esther Ugo Alum, Ifenayi Harrison Ofoke, Basil Uchechukwu Nwali, Angela Mumbua Musyoka, Victor Fasogbon Ilembayo   +9 more
doaj   +1 more source

Effect of Swimming Training with Hesperidin on Gene Expression Related Dopaminergic Neuron Survival in an Animal Model of Parkinson\'s Disease [PDF]

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd
Introduction: Parkinson's disease (PD) is a neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons in the substantia nigra. Antioxidant consumption and exercise may be important for these neurons’ survival.
Asma Taraz, Mehrzad Moghadasi, Zahra Mosalanezhad, Somayeh Rashidfard   +3 more
doaj  

Amelioration of cognition by hesperidin-conjugated cobalt oxide nanoparticles

Scientific Reports
Diabetes mellitus is one of the metabolic syndromes that is associated with cognitive deficit, dementia, and Alzheimer’s disease (AD) like pathology due to impaired insulin-signalling in the brain, oxidative stress and mitochondrial dysfunction ...
Anindita Behera, Bibhanwita Satpathy, Rajesh Kumar Sahoo, Pratap Kumar Sahu   +3 more
doaj   +1 more source

Bee Venom and Hesperidin Effectively Mitigate Complete Freund’s Adjuvant-Induced Arthritis Via Immunomodulation and Enhancement of Antioxidant Defense System

The Turkish Journal of Gastroenterology, 2018
Objectives: This study aims to assess the antirheumatic activity of bee venom (BV) and/or hesperidin as natural products in complete Freund’s adjuvant (CFA)-induced arthritis in male Wistar rats. Material and methods: Rheumatoid arthritis was induced
Osama AHMED, Hanaa FAHIM, Ayman MAHMOUD, Eman AHMED   +3 more
doaj