Results 51 to 60 of about 11,595 (185)

Influence of hesperidin and vitamin C on glycemic parameters, lipid profile, and DNA damage in rats treated with sucrose overload

open access: yesAnais da Academia Brasileira de Ciências, 2018
We evaluated the influence of hesperidin and vitamin C (VitC) on glycemic parameters, lipid profile, and DNA damage in male Wistar rats treated with sucrose overload.
SILVIA I.R. FRANKE   +6 more
doaj   +1 more source

From nature to nanoscale: advances, challenges, and preclinical translation of nanofiber drug delivery systems containing plant‐derived active ingredients

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat   +7 more
wiley   +1 more source

Potentiation of Antidepressant Effects of Agomelatine and Bupropion by Hesperidin in Mice

open access: yesNeurology Research International, 2018
Hesperidin, a well-known flavanone glycoside mostly found in citrus fruits, showed neuroprotective and antidepressant activity. Agomelatine, a melatonergic MT1/MT2 agonist and 5-HT2C receptor antagonist, exhibits good antidepressant efficacy.
Jegan Sakthivel Nadar   +4 more
doaj   +1 more source

Mangiferin and Hesperidin Transdermal Distribution and Permeability through the Skin from Solutions and Honeybush Extracts (Cyclopia sp.)—A Comparison Ex Vivo Study

open access: yesMolecules, 2021
Polyphenolic compounds—mangiferin and hesperidin—are, among others, the most important secondary metabolites of African shrub Cyclopia sp. (honeybush).
Anna Hering   +4 more
doaj   +1 more source

Soybean induced resistance to Spodoptera eridania herbivory

open access: yesPest Management Science, EarlyView.
SOD, CAT, APX, PPO, KTI, and MDA levels were higher in the resistant soybean. S. eridania herbivory increased H2O2 and MDA, but decreased SOD and PPO levels. S. eridania herbivory increased KTI activity only in the resistant variety. Isoquercitrin and daidzin were exclusive to resistant and susceptible soybeans.
Bruno Henrique Sardinha de Souza   +6 more
wiley   +1 more source

Hesperidin inhibits the epithelial to mesenchymal transition induced by transforming growth factor-β1 in A549 cells through Smad signaling in the cytoplasm

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2019
Hesperidin, a natural compound, suppresses the epithelial-to-mesenchymal transition through the TGF-β1/Smad signaling pathway. However, studies on the detailed effects and mechanisms of hesperidin are rare.
Zhouxin Ren   +5 more
doaj   +1 more source

Feiwei Heji Enhances Antitumor Immunity by MLL4‐Dependent Regulation of Pyroptosis in Lung Cancer

open access: yesCancer Science, EarlyView.
Feiwei Heji suppresses lung tumor growth by downregulating MLL4 and activating caspase‐1/GSDMD‐associated pyroptosis. This pyroptosis‐related inflammatory response enhances CD8+ T‐cell‐mediated antitumor immunity, revealing an MLL4‐pyroptosis‐immune axis underlying the therapeutic activity of Feiwei Heji.
Nan Cheng   +6 more
wiley   +1 more source

Hesperidin as a preventive resistance agent in MCF–7 breast cancer cells line resistance to doxorubicin

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2014
Objective: To evaluate of hesperidin to overcome resistance of doxorubicin in MCF-7 resistant doxorubicin cells (MCF-7/Dox) in cytotoxicity apoptosis and P-glycoprotein (Pgp) expression in combination with doxorubicin.
Rifki Febriansah   +5 more
doaj   +1 more source

Molecular Mechanisms of Food Bioactive Constituents in the Management of Obesity and Hypertension: A Critical Review

open access: yesPhytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.
Obesity and hypertension co‐exist and share molecular mechanisms in terms of dietary therapy, modulated by food bioactive constituents. ABSTRACT Obesity and hypertension are among the most pressing global public health challenges. They frequently co‐exist, with obesity‐related hypertension accounting for an estimated 75% of the hypertension burden ...
Samuel Oluwasegun Maccarthy   +3 more
wiley   +1 more source

Physiological regulation mechanism of hesperidin and the application in animal production

open access: yesSiliao yanjiu, 2021
Hesperidin is a natural plant feed additive, which has physiological activity of antioxidant, anti-inflammatory, antibacterial and anticancer activities.
Qing LIU, Yun XU
doaj  

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