Results 51 to 60 of about 14,514 (211)

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

Phytotherapy Research, EarlyView.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández, Sara Elis Bianchi, Flávia Nathiely Silveira Fachel, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +5 more
wiley   +1 more source

Biomimetic MCC950‐loaded cerium‐layered double hydroxide nanoparticles for targeted treatment of Type 1 diabetes in streptozotocin‐induced mice

British Journal of Pharmacology, EarlyView.
The CLMBM nanoparticle (NP) system demonstrates strong and targeted anti‐ROS, antiapoptotic and anti‐inflammatory properties within the pancreas, thereby inhibiting the onset and progression of type 1 diabetes. Background and Purpose The destruction of β‐cells in type 1 diabetes is driven by signalling cascades that ultimately lead to cell apoptosis ...
Huiwen Pang, Zhuo Chen, Youzhi Wu, Thanh‐Truc Nguyen, Jingjing Wang, David M. Klyne, Zhi Ping Xu, Chen Chen, Alan Rowan, Felicity Y. Han   +9 more
wiley   +1 more source

Inhibition of Fat Accumulation by Hesperidin in Caenorhabditis elegans

, 2016
Hesperidin, abundant in citrus fruits, has a wide range of pharmacological effects, including anticarcinogenic, anti-inflammatory, antioxidative, radioprotective, and antiviral activities.
Hujie Luo (2830184), Huimin Peng (400123), Xiangliang Yang (322746), Yiting Yang (2830190), Zhaohan Wei (2830187), Lu Gan (33435), Zhengxing Wu (2830193)   +6 more
core   +1 more source

Hesperidin meningkatkan doxorubicin pada sel MCF-7 efek sitotoksik = Hesperidin . increase cytotoxic effect of doxorubicin in MCF-7 cells

, 2010
Hesperidin, senyawa flavonoid menunjukkan efek toksik pada beberapa sel kanker. Tujuan penelitian Inl adalah untuk mengetahui aktlvltas sitotoksik hesperidin tunggal dan kombinasinya dengan doxorubicin pada sel MCF-7. Vilabilitas sel perlakuan hesperidin,
Adam Hermawan, Edy Meiyanto , Ratna Asmah Susidarti
core   +1 more source

Chitosan‐induced modulation of secondary metabolism and stress tolerance in Salvia rosmarinus under combined drought and heat stress

Journal of the Science of Food and Agriculture, Volume 106, Issue 10, Page 5989-6001, 15 August 2026.
Abstract BACKGROUND Abiotic stresses, particularly drought and elevated temperatures, negatively affect plant physiological and metabolic processes. This study investigated the effects of drought, heat, and combined stress on Salvia rosmarinus (rosemary), and evaluated foliar‐applied chitosan as a biostimulant.
Inês Mansinhos, Sandra Gonçalves, Raquel Rodríguez‐Solana, Efrén Pérez‐Santín, María I Fernández‐Marín, Emma Cantos‐Villar, Anabela Romano   +6 more
wiley   +1 more source

Potentiation of Antidepressant Effects of Agomelatine and Bupropion by Hesperidin in Mice

Neurology Research International, 2018
Hesperidin, a well-known flavanone glycoside mostly found in citrus fruits, showed neuroprotective and antidepressant activity. Agomelatine, a melatonergic MT1/MT2 agonist and 5-HT2C receptor antagonist, exhibits good antidepressant efficacy.
Jegan Sakthivel Nadar, Pravin Popatrao Kale, Pramod Kerunath Kadu, Kedar Prabhavalkar, Ruchita Dhangar   +4 more
doaj   +1 more source

Hesperidin inhibits the epithelial to mesenchymal transition induced by transforming growth factor-β1 in A549 cells through Smad signaling in the cytoplasm

Brazilian Journal of Pharmaceutical Sciences, 2019
Hesperidin, a natural compound, suppresses the epithelial-to-mesenchymal transition through the TGF-β1/Smad signaling pathway. However, studies on the detailed effects and mechanisms of hesperidin are rare.
Zhouxin Ren, Junling Shen, Xiaofeng Mei, Haoran Dong, Jiansheng Li, Haibin Yu   +5 more
doaj   +1 more source

Valorization of fruit pits from Prunus laurocerasus and Prunus cerasifera as agro‐food byproducts: Bioactive properties and safety assessment for potential food additive applications

Journal of the Science of Food and Agriculture, Volume 106, Issue 10, Page 6002-6014, 15 August 2026.
Abstract BACKGROUND Food additives are widely used to extend the shelf life of foods and maintain their quality. In this study, the potential of Prunus laurocerasus and Prunus cerasifera fruit pits (endocarp and seed) as food additives was investigated in terms of cytotoxicity, antigenotoxicity, antioxidant activity, enzymatic anti‐browning, and urease
Zühal Bayrakçeken Güven, Mehmet Karadayı, Mustafa Abdullah Yilmaz, Osman Tugay, Oguz Cakir   +4 more
wiley   +1 more source

Rational Design of Cyclodextrin Glycosyltransferase with Improved Hesperidin Glycosylation Activity

, 2023
Cyclodextrin glycosyltransferase (CGTase) can catalyze the glycosylation of hesperidin, resulting in α-glycosyl hesperidin with significantly improved water solubility.
Hanchi Chen, Yongfan Chen, Linjiang Zhu, Xiaolong Chen, Chunfeng Wang, Yuele Lu, Jiajun Wang, Yi Liu   +7 more
core   +1 more source

Physiological regulation mechanism of hesperidin and the application in animal production

Siliao yanjiu, 2021
Hesperidin is a natural plant feed additive, which has physiological activity of antioxidant, anti-inflammatory, antibacterial and anticancer activities.
Qing LIU, Yun XU
doaj