Results 31 to 40 of about 14,514 (211)

The pharmacological potential of hesperidin

, 2019
The modern scientific society has presently recognized flavonoids to be a unique class of therapeutic molecules due to their varied therapeutic properties.
Saluja, Ajay, Ganeshpurkar, Aditya
core   +1 more source

Migraine susceptibility is modulated by food triggers and analgesic overuse via sulfotransferase inhibition

The Journal of Headache and Pain, 2022
Background/aim Certain constituents in migraine food triggers and non-steroidal anti-inflammatory drugs (NSAIDs) inhibit sulfotransferases (SULTs) that detoxify drugs/chemicals and play role in the metabolism of neurotransmitters.
Doga Vuralli, Burak Arslan, Elif Topa, Andreia Lopes de Morais, Ozlem Gulbahar, Cenk Ayata, Hayrunnisa Bolay   +6 more
doaj   +1 more source

Hesperidin abrogates bisphenol A endocrine disruption through binding with fibroblast growth factor 21 (FGF-21), α-amylase and α-glucosidase: an in silico molecular study

Journal of Genetic Engineering and Biotechnology, 2022
Background Fibroblast growth factor 21 (FGF-21), alpha-amylase, and alpha-glucosidase are key proteins implicated in metabolic dysregulations. Bisphenol A (BPA) is an environmental toxicant known to cause endocrine dysregulations.
P. M. Aja, J. N. Awoke, P. C. Agu, A. E. Adegboyega, E. M. Ezeh, I. O. Igwenyi, O. U. Orji, O. G. Ani, B. A. Ale, U. A. Ibiam   +9 more
doaj   +1 more source

Intravitreal Kinetics of Hesperidin, Hesperetin, and Hesperidin G: Effect of Dose and Physicochemical Properties [PDF]

Journal of Pharmaceutical Sciences, 2012
Hesperidin, a flavanone glycoside, and its aglycone hesperetin are potential candidates for the treatment of diabetic retinopathy and macular edema. The objective of this study was to delineate vitreal pharmacokinetics of hesperidin and hesperetin and the hydrophilic derivative glucosyl hesperidin (hesperidin G) following intravitreal administration in
Ramesh, Srirangam, Ketan, Hippalgaonkar, Soumyajit, Majumdar   +2 more
openaire   +2 more sources

Microbial Transformation of Hesperidin and Biological Evaluation

ACS Omega, 2023
The main aim of the study was the biotransformation evaluation of hesperidin for functionalization by 25 different nonhuman pathogenic microorganisms. As a result, four metabolites were identified and characterized. The structure of pinocembrin and naringenin from the microbial transformation of hesperidin was determined initially with LC/MS-MS.
Damla Kırcı, Fatih Demirci, Betül Demirci   +2 more
openaire   +4 more sources

Short-Term Hesperidin Pretreatment Attenuates Rat Myocardial Ischemia/Reperfusion Injury by Inhibiting High Mobility Group Box 1 Protein Expression via the PI3K/Akt Pathway

Cellular Physiology and Biochemistry, 2016
Background/Aims: Hesperidin pretreatment has been shown to protect against myocardial ischemia/reperfusion (I/R) injury, but the underlying mechanism is poorly understood. This study aimed to investigate the cardioprotective effects of a 3-day hesperidin
Xuefei Li, Xiaorong Hu, Jichun Wang, Weipan Xu, Chunfeng Yi, Ruisong Ma, Hong Jiang   +6 more
doaj   +1 more source

Protective Effect of Hesperidin against Cyclophosphamide Hepatotoxicity in Rats [PDF]

, 2014
The protective effect of hesperidin was investigated in rats exposed to liver injury induced by a single intraperitoneal injection of cyclophosphamide (CYP) at a dose of 150 mg kg-1.
Iyad Jresat, Amr A. Fouad, Waleed H. Albuali   +2 more
core   +1 more source

Hesperidin attenuates arsenic trioxide-induced cardiac toxicity in rats [PDF]

, 2023
Objective: To explore the cardioprotective effect of hesperidin against arsenic trioxide-induced cardiac toxicity in rats. Methods: Cardiac toxicity was induced by oral administration of 4 mg/kg arsenic trioxide for 30 days.
Gayatri Khuntia, Subash Chandra Parija, Biswadeep Jena, Uma Kanta Mishra, Jeevan Ranjan Dash   +4 more
core   +1 more source

Selenium Nanomaterials for Wound Healing: Synergistic Strategies from Anti‐Infection to Tissue Regeneration

Advanced NanoBiomed Research, EarlyView.
Selenium nanoparticles (SeNPs) are emerging as multifunctional platforms for wound healing, integrating antimicrobial, anti‐inflammatory, and proregenerative activities. This review summarises key mechanisms and recent advances in SeNP‐enabled composite dressings, immunomodulatory nanocomposites, microenvironment‐responsive hydrogels, photothermal and ...
Yangxia Chen, Xiaoshuang Liang, Sirui Li, Shuoshan Li, Wei Liu, Yingping Lin, Siqi Li, Zehang Zhang, Judun Zheng, Tianfeng Chen, Rongyi Chen   +10 more
wiley   +1 more source

In Vitro Activity of Citrus IntegroPectin Against Breast Cancer and Colon Cancer

ChemFoodChem, EarlyView.
Image shows microscopic photographs of MCF‐7 cells in the presence of lemon, red orange, and sweet orange IntegroPectin bioconjugates at 0.5 or 1.0 mg/mL concentration after 24 h next to a photograph of MCF‐7 cells as such (control). ABSTRACT We investigate the ability of IntegroPectin bioconjugates obtained via acoustic cavitation of lemon, red orange,
Claudia D'Anna, Caterina Di Sano, Giovanna Li Petri, Giuseppe Angellotti, Rosaria Ciriminna, Mario Pagliaro   +5 more
wiley   +1 more source