Results 11 to 20 of about 22,445 (236)

Hesperidin Suppresses the Proliferation of Prostate Cancer Cells by Inducing Oxidative Stress and Disrupting Ca2+ Homeostasis

open access: yesAntioxidants, 2022
Although androgen deprivation therapy is mainly used for its treatment, the mortality rate of prostate cancer remains high due to drug resistance. Hence, there is a need to discover new compounds that exhibit therapeutic effects against prostate cancer ...
Seon Ae Jeong   +5 more
doaj   +1 more source

Improvement of low‐intensity long‐time running performance in rats by intake of glucosyl hesperidin

open access: yesPhysiological Reports, 2023
Recently, the use of ergogenic aids in sports by both athletes and fans has increased. Moreover, the overall demand for new ergogenic aids has increased.
Suminori Nagayama   +5 more
doaj   +1 more source

Investigation of the histopathological level of Ki-67, caspase-3 expressions of the effects of hesperidin on wound healing in the rat esophagus

open access: yesActa Cirúrgica Brasileira, 2023
Purpose: The effects of hesperidin application on the wound caused by esophageal burns were investigated in this study. Methods: Wistar albino rats were divided into three groups: Control group: only 1 mL of 0.09% NaCl was administered i.p. for 28 days;
Cemalettin Durgun   +2 more
doaj   +1 more source

Hesperidin plays beneficial roles in disorders associated with the central nervous system: a review

open access: yesInternational Journal of Food Properties, 2023
Significant levels of flavonoids with antioxidant properties can be found in citrus species. Flavonoids are a class of plant chemical known for a wide range of pharmacological activities. Notable among these flavonoids is Hesperidin.
Ayomide Victor Atoki   +4 more
doaj   +1 more source

Hesperidin Ameliorates Dexamethasone-Induced Osteoporosis by Inhibiting p53

open access: yesFrontiers in Cell and Developmental Biology, 2022
Osteoporosis is one of the most frequent skeletal disorders and a major cause of morbidity and mortality in the expanding aging population. Evidence suggests that hesperidin may have a therapeutic impact on osteoporosis.
Meng Zhang   +15 more
doaj   +1 more source

The Antidepressant-Like Effects of Hesperidin in Streptozotocin‐Induced Diabetic Rats by Activating Nrf2/ARE/Glyoxalase 1 Pathway

open access: yesFrontiers in Pharmacology, 2020
The co-occurrence of diabetes and depression is a challenging and underrecognized clinical problem. Alpha-carbonyl aldehydes and their detoxifying enzyme glyoxalase 1 (Glo-1) play vital roles in the pathogenesis of diabetic complications, including ...
Xia Zhu   +5 more
doaj   +1 more source

Hesperidin Anti-Osteoporosis by Regulating Estrogen Signaling Pathways

open access: yesMolecules, 2023
Osteoporosis (OP) is distinguished by a reduction in bone mass and degradation of bone micro-structure, frequently resulting in fractures. As the geriatric demographic expands, the incidence of affected individuals progressively rises, thereby exerting a
Hong-Yao Hu   +5 more
doaj   +1 more source

Screening the effect of four ultrasound-assisted extraction parameters on hesperidin and phenolic acid content of aqueous citrus pomace extracts [PDF]

open access: yes, 2018
Polyphenols of citrus by-products, due to their antioxidant and antimicrobial activities, could be valorized by pharmaceutical and food industries, adding a value to the citrus processing companies.
Bowyer, Michael C.   +6 more
core   +2 more sources

Hesperidin depolarizes the pacemaker potentials through 5-HT4 receptor in murine small intestinal interstitial cells of Cajal

open access: yesAnimal Cells and Systems, 2020
Hesperidin, a citrus flavonoid, can exert numerous beneficial effects on human health. Interstitial cells of Cajal (ICC) are pacemaker cells in the gastrointestinal (GI) tract.
Minwoo Hwang   +2 more
doaj   +1 more source

Insight into the Inhibitory Mechanisms of Hesperidin on α-Glucosidase through Kinetics, Fluorescence Quenching, and Molecular Docking Studies

open access: yesFoods, 2023
The α-glucosidase inhibitor is of interest to researchers due to its association with type-II diabetes treatment by suppressing postprandial hyperglycemia. Hesperidin is a major flavonoid in orange fruit with diverse biological properties.
Kumaravel Kaliaperumal   +6 more
doaj   +1 more source

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