Results 21 to 30 of about 14,514 (211)

Hesperidin Ameliorates Dexamethasone-Induced Osteoporosis by Inhibiting p53

Frontiers in Cell and Developmental Biology, 2022
Osteoporosis is one of the most frequent skeletal disorders and a major cause of morbidity and mortality in the expanding aging population. Evidence suggests that hesperidin may have a therapeutic impact on osteoporosis.
Meng Zhang, Meng Zhang, Delong Chen, Ning Zeng, Zhendong Liu, Zhendong Liu, Xiao Chen, Xiao Chen, Hefang Xiao, Hefang Xiao, Likang Xiao, Likang Xiao, Zeming Liu, Yonghui Dong, Yonghui Dong, Jia Zheng   +15 more
doaj   +1 more source

The Antidepressant-Like Effects of Hesperidin in Streptozotocin‐Induced Diabetic Rats by Activating Nrf2/ARE/Glyoxalase 1 Pathway

Frontiers in Pharmacology, 2020
The co-occurrence of diabetes and depression is a challenging and underrecognized clinical problem. Alpha-carbonyl aldehydes and their detoxifying enzyme glyoxalase 1 (Glo-1) play vital roles in the pathogenesis of diabetic complications, including ...
Xia Zhu, Haiyan Liu, Yuan Liu, Yajing Chen, Yaowu Liu, Xiaoxing Yin   +5 more
doaj   +1 more source

Hesperidin Anti-Osteoporosis by Regulating Estrogen Signaling Pathways

Molecules, 2023
Osteoporosis (OP) is distinguished by a reduction in bone mass and degradation of bone micro-structure, frequently resulting in fractures. As the geriatric demographic expands, the incidence of affected individuals progressively rises, thereby exerting a
Hong-Yao Hu, Ze-Zhao Zhang, Xiao-Ya Jiang, Tian-Hua Duan, Wei Feng, Xin-Guo Wang   +5 more
doaj   +1 more source

Hesperidin depolarizes the pacemaker potentials through 5-HT4 receptor in murine small intestinal interstitial cells of Cajal

Animal Cells and Systems, 2020
Hesperidin, a citrus flavonoid, can exert numerous beneficial effects on human health. Interstitial cells of Cajal (ICC) are pacemaker cells in the gastrointestinal (GI) tract.
Minwoo Hwang, Jeong Nam Kim, Byung Joo Kim   +2 more
doaj   +1 more source

A High-Yield Process for Production of Biosugars and Hesperidin from Mandarin Peel Wastes

Molecules, 2020
In this research, novel biorefinery processes for obtaining value-added chemicals such as biosugar and hesperidin from mandarin peel waste (MPW) are described.
Eun Jin Cho, Yoon Gyo Lee, Jihye Chang, Hyeun-Jong Bae   +3 more
doaj   +1 more source

Insight into the Inhibitory Mechanisms of Hesperidin on α-Glucosidase through Kinetics, Fluorescence Quenching, and Molecular Docking Studies

Foods, 2023
The α-glucosidase inhibitor is of interest to researchers due to its association with type-II diabetes treatment by suppressing postprandial hyperglycemia. Hesperidin is a major flavonoid in orange fruit with diverse biological properties.
Kumaravel Kaliaperumal, Linyan Zhang, Liangliang Gao, Qin Xiong, Yan Liang, Yueming Jiang, Jun Zhang   +6 more
doaj   +1 more source

Hesperidin Interacts With CREB-BDNF Signaling Pathway to Suppress Pentylenetetrazole-Induced Convulsions in Zebrafish

Frontiers in Pharmacology, 2021
Hesperidin (3,5,7-trihydroxyflavanone 7-rhamnoglucoside) is a β-7-rutinoside of hesperetin (4′-methoxy-3′,5,7-trihydroxyflavanone), abundantly found in citrus fruits and known to interact with various cellular pathways to show a variety of ...
Pallavi Sharma, Pallavi Sharma, Savita Kumari, Savita Kumari, Jatin Sharma, Rituraj Purohit, Rituraj Purohit, Damanpreet Singh, Damanpreet Singh   +8 more
doaj   +1 more source

The flavonoid hesperidin exerts anti-photoaging effect by downregulating matrix metalloproteinase (MMP)-9 expression via mitogen activated protein kinase (MAPK)-dependent signaling pathways

BMC Complementary and Alternative Medicine, 2018
Background Hesperidin is a flavonoid with antioxidant, anti-inflammatory, and immune modulatory activities. Photoaging is a consequence of chronic exposure to the sun and ultraviolet (UV) radiation.
Hee Jeong Lee, A-Rang Im, Su-Man Kim, Hyung-Sik Kang, Jae Dong Lee, Sungwook Chae   +5 more
doaj   +1 more source

Recovery of pure Hesperidin from Iraqi Sweet Oranges Peel and study the effect in some bacteria

مجلة بغداد للعلوم, 2014
Citrus fruit contain variety of flavonoids such as Hesperidin (the principal flavonoid in oranges and grapefruit). Hesperidin is found in high concentration in fruit peel of oranges and in substantially lower concentration in juice of these fruits ...
Baghdad Science Journal
doaj   +1 more source

Inhibitory Effects of Hesperidin Glycosides on Precipitation of Hesperidin.

NIPPON SHOKUHIN KAGAKU KOGAKU KAISHI, 1998
ヘスペリジン配糖体をみかん缶詰に添加し,室温で保存し,1,3,6か月後にその白濁防止効果について検討した.その結果,ヘスペリジン配糖体は0.004%という非常に低濃度で,効果的にみかん缶詰シラップの白濁を抑制した.さらに溶存ヘスペリジン量は,シラップの透明度が増加するに従い増加していた.つまり,ヘスペリジンの白濁防止効果はヘスペリジン配糖体によるヘスペリジンの可溶化効果に起因していることが明らかとなった.またこの効果は,高い殺菌温度および酸度の影響を受けることなく安定していた.ヘスペリジン配糖体のヘスペリジン可溶化効果を果汁含有率50%のオレンジ果汁飲料に応用した.ヘスペリジン配糖体をオレンジ果汁飲料に0.05%添加して6か月間静置後,沈殿画分および上清画分に存在するヘスペリジン量を定量した結果 ...
NISHIMURA, Takahisa, KOMETANI, Takashi, OKADA, Shigetaka, KOBAYASHI, Yoshinori, FUKUMOTO, Syunichi   +4 more
openaire   +2 more sources