Results 71 to 80 of about 11,595 (185)

In Vitro Evaluation of Cytotoxic and Pro-Apoptotic Effects of Hesperidin Alone and in Combination with Cisplatin on Human Malignant Melanoma Cell Line (A431)

Pharmaceuticals
Background/Objectives: Melanoma is an aggressive skin cancer with high metastatic potential and poor prognosis in advanced stages. Hesperidin, a natural flavonoid, has shown anticancer properties across various malignancies.
Mehmet Uğur Karabat, Mehmet Cudi Tuncer, İlhan Özdemir   +2 more
doaj   +1 more source

New Insights Into the Phytochemical Composition and Biological Potential of Leaf Extracts From Algerian Autochthonous Vitis vinifera L.

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Phenolic‐rich extracts from five indigenous Algerian Vitis vinifera leaf cultivars were characterized by LC–MS and evaluated for antioxidant, antidiabetic, antibacterial, and molecular docking activities. The Azorith‐fereinguel cultivar showed superior bioactivity, attributed mainly to isoquercitrin, hesperidin, and rutin.
Radhia Belmanaa, Azzeddine Zeraib, Ziane Laiadi, Ahmed Simozrag, Khadra Afaf Bendrihem, Ayomide Victor Atoki, Mohammed Messaoudi   +6 more
wiley   +1 more source

Ueber Hesperidin [PDF]

Archiv der Pharmazie
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openaire   +2 more sources

Effects of Long-Term Administration of Hesperidin and Glucosyl Hesperidin to Spontaneously Hypertensive Rats.

Journal of Nutritional Science and Vitaminology, 2002
Hesperidin (HES) is a flavonoid contained in citrus fruit peel. We investigated the effects of long-term administration of HES and its newly developed water soluble analogue, glucosyl hesperidin (GHES), to spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto rats (WKY).
OHTSUKI, Kazumasa, ABE, Asaki, MITSUZUMI, Hitoshi, KONDO, Masaru, UEMURA, Kanae, IWASAKI, Yumiko, KONDO, Yasuhiro   +6 more
openaire   +3 more sources

The neuroprotective effect of hesperidin in NMDA-induced retinal injury acts by suppressing oxidative stress and excessive calpain activation

Scientific Reports, 2017
We found that hesperidin, a plant-derived bioflavonoid, may be a candidate agent for neuroprotective treatment in the retina, after screening 41 materials for anti-oxidative properties in a primary retinal cell culture under oxidative stress.
Shigeto Maekawa, Kota Sato, Kosuke Fujita, Reiko Daigaku, Hiroshi Tawarayama, Namie Murayama, Satoru Moritoh, Takeshi Yabana, Yukihiro Shiga, Kazuko Omodaka, Kazuichi Maruyama, Koji M. Nishiguchi, Toru Nakazawa   +12 more
doaj   +1 more source

Comparative Phytochemical Profiles and Antioxidant Potential of Green and Variegated Morphotypes of Alternanthera bettzickiana Under Optimized Extraction Conditions

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Green and variegated Alternanthera bettzickiana morphotypes were compared after optimizing extraction (Box–Behnken design–RSM: 90% ethanol, 50°C, 2 h, 10 mg/mL). The green morphotype had higher phenolic content, FRAP, and ORAC activity, while the variegated morphotype had higher flavonoid and anthocyanin content.
Sirinapa Thangsiri, Woorawee Inthachat, Piya Temviriyanukul, Amornrat Aursalung, Yuraporn Sahasakul, Uthaiwan Suttisansanee   +5 more
wiley   +1 more source

Phytochemical Characterization and Bioactive Potential of Stachys germanica L.: LC–MS/MS Profiling and Multi‐Target Biological Activities

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
The 80% ethanolic extract of Stachys germanica L. exhibited a phenolic‐rich phytochemical profile characterized by chlorogenic acid, naringin, luteolin, and kaempferol. The extract demonstrated notable antioxidant capacity, selective tyrosinase and α‐glucosidase inhibition, and significant antibacterial activity against Acinetobacter baumannii ATCC ...
Gözde Gülin İnan, Derya Doğanay, Yiğit İnan, Selin Akyüz‐Çetin, Neşet Neşetoğlu, İbrahim Daniş, Esra Mertoğlu, Durişehvar Özer Ünal, Gokhan Zengin   +8 more
wiley   +1 more source

Hesperidin: A Therapeutic Agent For Obesity.

Drug design, development and therapy, 2019
Obesity is a chronic metabolic disease caused by multiple factors and is considered to be a risk factor for type 2 diabetes, cardiovascular disease, hypertension, stroke and various cancers. Hesperidin, a flavanone glycoside, is a natural phenolic compound with a wide range of biological effects.
Xiong,Haijun, Wang,Jin, Ran,Qian, Lou,Guanhua, Peng,Chengyi, Gan,Qingxia, Hu,Ju, Sun,Jilin, Yao,Renchuan, Huang,Qinwan   +9 more
openaire   +4 more sources

Valorisation of Pea Pod by‐Product Through Lactic Acid Bacteria Fermentation and Application in Cookie Production

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Pea pod by‐products were valorised through fermentation with lactic acid bacteria and applied in cookie production. Fermentation enhanced antioxidant activity, particularly after 24 h with L. casei DD_B_B71. Cookies with fermented flour showed improved bioactive profiles, though sensory optimisation is needed, highlighting a promising approach for ...
Dilara Devecioglu, Berfin Kaya, Neris Danç, Aysegul Mutlu‐Ingok, Funda Karbancioglu‐Guler   +4 more
wiley   +1 more source

Hesperidin ameliorates H2O2-induced bovine mammary epithelial cell oxidative stress via the Nrf2 signaling pathway

Journal of Animal Science and Biotechnology
Background Hesperidin is a citrus flavonoid with anti-inflammatory and antioxidant potential. However, its protective effects on bovine mammary epithelial cells (bMECs) exposed to oxidative stress have not been elucidated.
Qi Huang, Jiashuo Liu, Can Peng, Xuefeng Han, Zhiliang Tan   +4 more
doaj   +1 more source