Results 91 to 100 of about 22,445 (236)

In Vitro Evaluation of Cytotoxic and Pro-Apoptotic Effects of Hesperidin Alone and in Combination with Cisplatin on Human Malignant Melanoma Cell Line (A431)

Pharmaceuticals
Background/Objectives: Melanoma is an aggressive skin cancer with high metastatic potential and poor prognosis in advanced stages. Hesperidin, a natural flavonoid, has shown anticancer properties across various malignancies.
Mehmet Uğur Karabat, Mehmet Cudi Tuncer, İlhan Özdemir   +2 more
doaj   +1 more source

Foodborne Carcinogens: Formation Pathways, Health Risks, and Cutting‐Edge Physical and Chemical Prevention Strategies

eFood, Volume 7, Issue 3, June 2026.
This review highlights the formation of foodborne carcinogens during processing and evaluates different mitigation strategies, including natural antioxidants and modern cooking techniques, to reduce associated cancer risks and enhance food safety. ABSTRACT Food processing methods, though vital for improving food safety, taste, and shelf life, can ...
Naglaa S. Ashmawy, Ahmed A. Zaky, Noha H. Badr, Ali Korin, Mohamed A. Farag   +4 more
wiley   +1 more source

Phenolic Content, Antioxidant Activity, Phytochemical Diversity, and Toxicological Potential of Tetradenia riparia (Hochst.) Codd Leaves

Chemistry &Biodiversity, Volume 23, Issue 5, May 2026.
ABSTRACT Tetradenia riparia (Hochst.) Codd is a medicinal plant widely used in traditional medicine. However, comprehensive studies integrating its chemical composition, antioxidant capacity, and toxicological safety are still limited. This study aimed to characterize the phenolic content, antioxidant activity, phytochemical diversity, and ...
Caroline dos Santos Giuliani, Carla Andressa Almeida Farias, Patrícia Kolling Marquezan, Karoline Longo de Aguiar, Elize Musachio, Andreara Rodrigues dos Reis, Nathália Cardoso de Afonso Bonotto, Fernanda Barbisan, Milene Teixeira Barcia, Ana Lúcia Souza Silva Mateus, Aline Sobreira Bezerra, José Laerte Nörnberg   +11 more
wiley   +1 more source

Point: From animal models to prevention of colon cancer. Systematic review of chemoprevention in min mice and choice of the model system. [PDF]

, 2003
The Apc(Min/+) mouse model and the azoxymethane (AOM) rat model are the main animal models used to study the effect of dietary agents on colorectal cancer. We reviewed recently the potency of chemopreventive agents in the AOM rat model (D. E.
Corpet, Denis E., Pierre, Fabrice
core   +2 more sources

Exploring the Functional Potential of Date (Phoenix dactylifera) Seed Bioactives in Modulating Gut Microbiota in Diabetic Rats

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Date fruits (Phoenix dactilyfera L.) are widely produced with huge wasted by‐products (seeds/pits and fibers) in remarkable nutritional and economic potential value. This study aims to examine the impact of the functional properties of date seeds on health status and gut microbiota (GM) modulation in diabetic rats. Valorization of date seed by‐products
Nouf Abdullah Alharbi, Saleh A. Asanie, Asmahan A. Ali, Aeshah Alhosain, Tarfa Albrahim, Thamer Aljutaily, Huda Aljumayi, Isam A. Mohamed Ahmed, Belal M. Mohammed, Nazeha A. Khalil   +9 more
wiley   +1 more source

Hesperidin ameliorates H2O2-induced bovine mammary epithelial cell oxidative stress via the Nrf2 signaling pathway

Journal of Animal Science and Biotechnology
Background Hesperidin is a citrus flavonoid with anti-inflammatory and antioxidant potential. However, its protective effects on bovine mammary epithelial cells (bMECs) exposed to oxidative stress have not been elucidated.
Qi Huang, Jiashuo Liu, Can Peng, Xuefeng Han, Zhiliang Tan   +4 more
doaj   +1 more source

Effects of flavonoids dietary supplementation on egg yolk antioxidant capacity and cholesterol level [PDF]

, 2014
An experiment was conducted to examine the effects of supplementing laying hen feed with different levels of hesperidin or naringin, bioflavonoids that are abundant and inexpensive by-products of citrus cultivation, on the yolk antioxidant capacity and ...
Charismiadou, M., Deligeorgis, S., Goliomytis, M., Kominakis, A., Papalexi, K., Simitzis, P., Veneti, N.   +6 more
core  

Fast simultaneous determination of prominent polyphenols in vegetables and fruits by reversed phase liquid chromatography using a fused-core column [PDF]

, 2015
A reversed-phase high-performance liquid chromatography method with photodiode array detection has been developed enabling the joint determination of 17 prominent flavonoids and phenolic acids in vegetables and fruits.
Cebolla-Cornejo, Jaime, Herrero Martínez, José Manuel, Martí, Raúl, Roselló, Salvador, Valcárcel, Mercedes   +4 more
core   +2 more sources

Pachymic Acid Alleviates Non‐Alcoholic Fatty Liver Disease via FGF21‐Mediated Inhibition of the p38 MAPK Pathway

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Pachymic acid alleviates non‐alcoholic fatty liver disease via FGF21‐mediated inhibition of the p38 MAPK pathway. Pachymic acid (PAC) exerts anti‐ non‐alcoholic fatty liver disease (NAFLD) effects by promoting FGF21 expression, activating FGF21/FGFR1 signaling, and thereby suppressing p38 MAPK phosphorylation. ABSTRACT Non‐alcoholic fatty liver disease
Lijuan Nie, Dehong Ma, Xinke Deng, Aga Erbu, Fanli Wang, Wenshuo Shi, Zixuan Li, Huantian Cui, Weibo Wen   +8 more
wiley   +1 more source

Hesperidin Plays Neuroprotective Effects Against Quinolinic Acid in Human SH-SY5Y Cells: Focusing on ROS Levels and Cell Cycle Arrest [PDF]

Research Journal of Pharmacognosy
Background and objectives: In some neurodegenerative diseases, an aberrant accumulation of quinolinic acid is frequently associated with the loss of nerve cells and a condition known as neuritis.
Farzaneh Abbasinezhad-Moud, Emad Azimi, Mehdi Rostami, Elaheh Gheybi, Mohammad Soukhtanloo*   +4 more
doaj   +1 more source